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20 Cards in this Set
- Front
- Back
- 3rd side (hint)
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MOA - inhibits Na-Cl cotransporter in distal tubule
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thiazide diuretic
eg hydrochlorothiazide (MAO) |
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MOA - inhibits Na-K-2Cl transporter in loop of henle
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loop diuretic
eg furosemide, ethacrinic acid (MOA) |
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MOA - blocks the Na channel in the collecting duct
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amiloride and triamterine
(MOA) |
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MOA - blocks aldosterone receptor
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spironolactone and eplerenone
(MOA) |
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MOA - inhbits carbonic anhydrase in proximal tubule
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carbonic anhydrase inhibitor
eg acetazolamide (MOA) |
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side effect - increased uric acid and gout
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thiazide diuretics
and loop diuretics (side effect) |
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side effect - hypokalemia
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thiazide, loop diuretics, carbonic anhydrase inhibitors
(side effect) |
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side effect - hyperkalemia
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K sparing diuretics
eg amiloride, triamterene, spironolactone (side effect) |
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side effect - metabolic acidosis
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carbonic anhydrase inhbitors
(side effect) |
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side effect - allergic reactions (which loop diuretic)
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furosemide
not ethacrynic acid |
looking for sulfonamide derivative
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side effect - ototoxicity
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ethacrynic acid
less with furosemide (side effect) |
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side effect - gynecomastia
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spironolactone
(not eplerenone) (endocrine side effect) |
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MOA - lose Ca
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loop diuretics
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MOA - increase Ca reabsorption
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thiazide diuretics
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MOA - alkalinize urine
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carbonic anhydrase inhibitors
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Clinical use - ascites
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spironolactone (first)
loop diuretic (possible add on) |
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Clinical use - acute hypercalcemia
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loop diuretic
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Clinical use - Calcium containing kidney stones
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thiazide diuretic
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Clinical use - edema from heart failure
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loop diuretic
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Clinical use - diuretic for open angle glaucoma
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dorzolamide
(topical agent) |
topical agent
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