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16 Cards in this Set
- Front
- Back
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Carbonic anhydrase inhibitors
site of action |
Proximal tubule
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Loop diuretics
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ascending loop of Henle
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Osmotic diuretics
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Proximal tubule
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Potassium sparing diuretics
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collecting duct
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Thiazide diuretics
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distal tubule
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Acetazolamide
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Diamox
CAI For: open angle glaucoma edema secondary to heart failure High alititude sickness NOT for: liver/kidney failure hypokalemia adrenal gland failure Can cause digitalis toxicity urticaria |
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Furosemide
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Lasix
Most common loop diuretic FOR: pulmonary edema edema r/t heart failure ascites (fluid in abd d/t liver failure) hypertension Rapid onset! - po 30-60 min IV - 5 minutes! Duration - PO - 6-8hr, IV - 2hr Adverse: hypokalemia, photosensitivity, exfoliative dermatitis, aplastic anemia, ototoxicity. If dosed too fast can cause hearing loss! |
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Mannitol
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Osmitrol
Osmotic diuretic weak diuretic FOR: cerebral edema, early renal failure NOT: peripheral edema IV must have filter |
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Spironolactone
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Aldactone
Ka sparing diuretic FOR: ascites, hypertension, hyperaldosteronism, heart failure. Common in pediatrics |
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Amiloride
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Midamor
Ka sparing diuretic combined with thiazide diuretics in heart failure Less effective long term. |
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hydrochlorothiazide
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HydroDIURIL
Thiazide diuretic safe, inexpensive Ceiling effect at 50mg/day toxicity = hypokalemia |
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Heparin
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anticoagulent
FOR: deep vein thrombosis prophylacticly - SQ/5000 units 2-3x/day, PE, clotting prevention SQ and IV (monitor PTT q6hr) |
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Enoxaparin
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Lovenox
anticoagulant, SQ only Commonly used in bridge therapy when transitioning off of others like Coumadin Used in post-MI, prevent thrombus. No need to monitor PTT |
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protamine sulfate
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IV antidote for heparin and lovenox
1mg for every 100mg of heparin 5 min to reduce effects 1mg to 1mg for LMWH |
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Vitamin K
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antidote for Warfarin
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Warfarin
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Coumadin
anticoagulent PO only, monitor INR Therapeutic INR 2-3.5 PT therapeutic is 18 seconds cautious with Vit K foods (green leafy vegies) |
