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6 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Thiazides
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Inhibit Na+Cl- symporter preventing reabsorption of Na+ in DCT Indication: HTN, Heart Failure, Diabetes insipidus, Kidney stones |
Hyponatremia, hypokalemia, hypercalcemia |
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Loop Diuretics |
Furosimide Inhibit Na+K+2Cl- in Thick aLOH preventing reabsorption of Na+. Indications: Acute pulmonary oedema, Heart Failure, Cirrhosis (ascites), Nephrotic, Renal Failure. |
SE: Hypovolemia, hypotension, hypokalemia |
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Amiloride/Triamterene |
Blocks sodium channels in collecting ducts, DECREASE K+ excretion from urine. Given together with loop diuretic and thiazide. |
SE: Hyperkalemia |
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Aldosterone Antagonist |
Spironolactone, Eplrenelone Inhibit aldosterone action on principle cells of collecting duct. Given together with loop diuretic or thiazide. |
SE: Hypoerkalemia, must monitor carefully in patients with renal impairment. |
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Osmotic Diuretics |
Mannitol Affects renal tubules and in plasma elsewhere. Weak diuretic, acts as a solute creating a conc gradient. Indication: Cerebral oedema, glaucoma |
SE: Expansion of ECF compartments, Hyponatremia |
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Carbonic Anhydrase Inhibitor |
Acetazolamide Works by excreting bicarbonate together Na+, K+ and water resulting in the flow of alkaline urine. |
SE: Metabolic Acidosis |
