Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
7 Cards in this Set
- Front
- Back
|
classification of diuretics |
|
|
|
osmotic diuretics |
mannitol,urea,glycerine,Isosorbide. Uses:prevention of anuria in acute renal failure,tx of acute cerebral and glaucoma,tx of dialysis disequilibrium syndrome,tx of cystic fibrosis. SE: overdosed expansion of EC fluid |
|
|
carbonic anhydrase inhibitors |
acetozolamide,brinzolamide,metazolamide,dichlorphenamide. Uses: 1.Kidney:dec in NaHCO3 reabsorption & H+ secretion 2.Eye(cilliary process & proximal tubular cells):dec aqueous humor production. 3.RBC:inc CO2 in tissue,in CNS CO2 exerts a weak GA effect. |
|
|
loop diuretics |
furosemide,bumetanide,torasemide,ethacrynic acid. SE:hypovolemia,hypokalemia,hypomagnesemia,hypocalcemia,hyperglycemia,hearing loss(by ethacrynic acid). Indications:acute pulmonary edema caused by HF,acute hypertensive crisis,acute renal failure,acute hypercalcemia Interactions:high PPB,dec tubular secretion of d drugs by acidic drugs.NSAIDS have antidiuretic effect.k+loss(increases effects of digitalis),mg2+loss(increases risk of arrythmia),na+loss(inc Li+reabsorption in proximal tubule). |
|
|
thiazides & thiazide like |
thiazides:chlorothiazide,hydrochlorothiazide. thiazidelike:clopamide,chlorthialidone,indapamide,metolazone SE:hypovolemia,hypokalemia,hypomagnesemia,hyperuricemia,hyperglycemia,hypercholesterolemia,hypercalcemia,erectile dysfunction Uses:hypertension,generalized edemas,Ca2+nephrolithiasis/osteoporosis,nephrogenic diabetes insipidus. |
|
|
na+channel antagonosists |
amiloride,triamterene SE:hyperkalemia,GI disturbance,triamterene effects(megaloblastic anemia,interstitial nephritis/crystalluria,photosensitization) Uses:weak diuretics,cystic fibrosis,Li+ intoxication |
|
|
aldosterone antagonists |
spironolactone,canernoate,eplerenone |
