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19 Cards in this Set

  • Front
  • Back
Bendroflumethiazide
Thiazide and related diuretic

Oedema in heart failiure
NO LONGER FIRST LINE IN HYPERTENSION
Chortalidone
Thiazide and related diuretic

Ascites in cirrhosis, oedema, hypertension, mild to moderate heart failure, diabetes insipidus.

Long duration of action, good for less compliant patients. Branded Hygroton.
Cyclopenthiazide
Thiazide and related diuretic

oedema and hypertension

Branded Navidrex
Indapamide
Thiazide and related diuretic

Used in hypertension, may lower BP with minimal metabolic disturbance, particularly diabetes mellitus.
Metolazone
Thiazide and related diuretic

oedema and hypertension

particularly effective when combined with a loop diuretic, even in renal failure.

PATIENTS MUST BE MONITORED CAREFULLY - profound diuresis
Xipamide
Thiazide and related diuretic

Oedema and hypertension

chemically related to chlortalidone.
Bumetanide
Loop diuretic

oedema

powerful diuretic. Acts within 1hr, complete in 6.
Furosemide (Frusemide)
Loop diuretic

Oedema

Powerful diuretic, acts within 1hr, complete in 6
Torasemide
Loop diuretic

similar to furosemide and bumetanide, but also licenced for hypertension
Amiloride
Potassium sparing diuretic

oedema, potassium conservation with loop or thiazide diuretics

weak diuretic effect, but allows for use of other diuretics without a potassium supplement
Triamterene
Potassium sparing diuretic

oedema, potassium conservation with loop or thiazide diuretics

weak diuretic effect, but allows for use of other diuretics without a potassium supplement
Eplenerone
Aldesterone antagonist (potassium sparing diuretic)

adjunct in LV dysfunction with evidence of HF after MI, and mild HF with LV dysfunction.
Spironolactone
Aldesterone antagonist (potassium sparing diuretic)

Oedema, ascites, CHF, moderate to severe HF, resistant hypertension [unlicenced] primary hyperaldesteronism
Mannitol
Osmotic diuretic

used to treat cerebral oedema, and raised intra-occular pressure.
Thiazide and related diuretics
May cause hypokalaemia, hyponatremia, and hyPER calcaemia.

Caution in liver disease, hypokalaemia may precipitate coma.

Ineffective if eGFR <30ml/min

DO NOT USE IN PREGNANCY
Loop diuretics
IV administration is of great benefit in pulmonary hypertension, giving relief before diuretic effect.

High doses/rapid admin can cause tinnitus or deafness.

Caution, may cause hypokalaemia. Caution in pts with liver damage.
Potassium sparing and aldesterone antagonists
whilst their diuretic effect is weak, they cause retention of potassium which may be of benefit in preventing hypokalaemia with other diuretics.

Potassium supplements must not be given alongside these drugs.
Potassium Sparing diuretics with other diuretics
Ideally prescribed individually, but where compliance is a problem, these are available as compound preparations.
Diuretics with Potassium
Most patients on diuretics will not require supplements. When they do, the amount of potassium in the compound preparations is often inadequate, and so their use is discouraged.

Considered less suitable for prescribing on the NHS