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20 Cards in this Set
- Front
- Back
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order of kidney structures
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proximal convooluted tubule
descending loop of Henle ascending loop of hensle distal convoluted tubule collecting tubule and duct |
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name CAI's
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Acetazolamide
Dorzolamide Methazolamide |
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mechanism of CAI
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inhibition of Carbonic anhydrase
decrease bicarbonate production decrease aquesous production |
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therapeutic uses of CAI
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glaucoma
POAG Acute angle closure Macular edema Mountain sickness |
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adverse effects of CAI
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metabolic acidosis
potassium depletion Renal stone formation paresthesia myopic shift |
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contraindications of CAI
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sulfa-allergy
liver failure sickle cell pregnancy renal calculus |
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Name Loop diuretics
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Bumetanide
furosemide torsemide ethacrynic acid |
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mechanism of loop diuretics
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decreased reabsorption fo Na, K CL
increase renal blood flow |
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therapeutic uses
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congestive heart failure #1
pulmonary edema |
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adverse effects of Loop
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ototoxicity
hyperuricemia aute hypovolemia potassium depletion #1 |
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Name Thiazides
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Chlorothiazide
Hydrochlorothiazide Chlorthalidone Metolazone Indapamide |
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Mechanism of thaizide
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increase excretion of Na & CL
loss of K+ dec. ca2+ excretion reduced peripheral vascular resistance urine is hyperosmolar |
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therapeutic uses of thiazides
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hypertension #1
CHF renal impairment diabetes insipidus |
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adverse effects of thiazides
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K+ dpletion
hyperuricemia hyperglycemia hypersensitivity |
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Name K+ sparing diuretics
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Spironolactone
Triamterene amiloride |
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mechanism of K+ sparing
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synethetic aldosterone antagonist
increase exc. of Na+ Retention of K+ |
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therapeutic uses of K+
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diuretic
secondary hyperaldosteronism |
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adverse effects of K+ diuretics
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gynecomastia
menstral irregularities |
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name osmotic diuretics
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mannitol
urea |
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mechanism of osmotic diuretics
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carry water with them inot the tubular fluid
act only by causing osmotic pressure load |
