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16 Cards in this Set
- Front
- Back
Carbonic anhydrase inhibitor
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Acetazolamide
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Diuretic used for mountain sickness and glaucoma
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Acetazolamide
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SE of Acetazolamide
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Parasthesias
Alkalinization of urine (may ppt Ca2+ salts) Hypokalemia Acidosis Encephalopathy in pts with hepatic impairment |
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MOA of loop diuretics
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inhibit Na+/K+/2Cl- cotransport
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Site of action of loop diuretics
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Thick ascending limb
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SE of loop (furosemide) diuretics
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Hyperuricemia
Hypokalemia Ototoxicity |
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Aminoglycosides used with loop diuretics potentiate this adverse effect
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Ototoxicity
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Loops lose and thiazide diuretics retain
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Calcium
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MOA of thiazide diuretics
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Inhibit Na+/Cl- cotransport
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Site of action of thiazide diuretics
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Early distal convoluted tubule
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Class of drugs that may cause cross-sensitivity with thiazide diuretics
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Sulfonamides
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SE of thiazide (HCTZ) diuretics
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Hyperuricemia
Hypokalemia Hyperglycemia |
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Potassium sparing diuretics inhibit
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Na+/K+ exchange
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Diuretic used to treat primary aldosteronism
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Spironolactone
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SE of spironolactone
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Gynecomastia
Hyperkalemia Impotence |
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Osmotic diuretic used to treat increased intracranial pressure
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Mannitol
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