Diuretics

Front 1

Carbonic Anyhydrase inhibitors cause

Back 1

decreased production of H2CO3 thus decreased H+ in cell, leading to decreased Na resorption and increased HCO3 in lumen

Front 2

Net result of Carbonic Anyhydrase is

Back 2

increased Na, K, and HCO3 excretion.

Front 3

Osmotic diuretics cause

Back 3

H2O to be drawn into lumen of tubules

Front 4

Thiazide diuretics inhibit what

Back 4

Na Cl symport
K is only effected in late distal tubule

Front 5

Acetazolamide is a

Back 5

Carbonic anhydrase inhibitor

Front 6

Mannitol is a

Back 6

Osmotic diuretic

Front 7

Furosemide is a

Back 7

Loop diuretics

Front 8

Chlorothiazide is a

Back 8

Thiazide diuretics

Front 9

Hydrochlorothiazide is a

Back 9

Thiazide diuretics

Front 10

Triamteren and Amiloride is an

Back 10

Inhibiotrs of renal epithelial sodium channels

Front 11

Spironolactone

Back 11

Antagonists of mineralocorticoid receptors - blocks aldosterone

Front 12

CA mechanism

Back 12

interferes with conversion of H2O + CO2 to H2CO3, thus decreased H+, leads to increased NaHCO2 and water excretion.

Front 13

CA electrolyte results

Back 13

Increased K+ excretion, via increased Na resorption in CD,
Increased P elimination.

Front 14

CA induces what metabolic condition

Back 14

metabolic acidosis.
alkaline urine

Front 15

CA adverse effects

Back 15

decrease ammonia excretion - worsens severity of pre-existing hepatic dz.
Increased secretion of weak bases

Front 16

CA contraindications

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with severe pulmonary disease cant respond to metabolic acidosis,
patients with electrolyte disturbances

Front 17

Mannitol electrolyte affects

Back 17

increased excretion of Na, K, Cl, Mg, HCO3

Front 18

Mannitol extrarenal action

Back 18

decreased hematocrit, and RBC volume.
increased cardiac output,

Front 19

Furosemide MOA

Back 19

inhibit NA, K 2Cl symporter

Front 20

Types of Diuretics

Back 20

Cargonic anhydrase
Osmotic diuretics
Loop diuretics
Thiazide diuretics
Inhibitors of renal epithelium sodium channels
Aldosterone antagonist

Front 21

Acetozolamide is what type of drug

Back 21

Carbonic anhydrase inhibitor

Front 22

Mannitol is what type of drug

Back 22

osmotic diruetic

Front 23

Furosemide is what type of drug

Back 23

Loop diuretic

Front 24

Chlorothiazide hydropchlorothiazide is what type of drug

Back 24

Thiazide diuretic

Front 25

Triamterene Amiloride is what type of drug

Back 25

inhibitor of renal epithelium sodium channels

Front 26

Spironolactone is what type of drug

Back 26

Aldosterone antagonist

Front 27

Acetozolamide acts where and does what

Back 27

Proximal tubule - inhibits CA, decrease protons pumped into lumen - NaHCO3 is formed in lumen and water follows

Front 28

Acetozolamide is used for

Back 28

decrease production of aqueous humor in the eye, manage glaucoma

Front 29

Acetozolamide is electrolyte effect

Back 29

increasing the excretion of Na/K

Front 30

Acetozolamide toxicity causes

Back 30

increased urine ph, metabolic acidosis

Front 31

Mannitol location of action

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Entire loop/nephron

Front 32

mannitol uses

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decrease intracranial/intraocular pressure

Front 33

Furosemide location of action is

Back 33

Thick ascending limb

Front 34

Furosemide mechanism

Back 34

Blocks Na/K/2Cl symporter

Front 35

Furosemide results in the

Back 35

increased excretion of Na, K, Cl, Ca, Mg