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19 Cards in this Set

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  • Back
What are some of the causes of mononeuropathy?
Compression, trauma, diabetes, vasculitis, radiation, & inflammation
What organism is most commonly responsible for osteomyelitis?
S. aureus
N. gonorrhea: sexually active
P. aeruginosa: drug users and diabetics
Salmonella: Sickle Cell patients
What is exstrophy of the bladder? What condition is associated with this abnormality?
Exstrophy of the bladder is associated with epispadia (abnormal opening of the penis on the superior (dorsal) side due to faulty positioning of the genital tubercule)
Mnemonic: you hit your eye when you pee
Which vitamins are fat soluble antioxiants?
Vitamin A and Vitamin E
Which vitamin is a mandatory injection for neonates to prevent deficiency?
Vitamin K
What are the signs of bacterial endocarditis?
Mnemonic: FROM JANE
Fever
Roth spots (retinal hemorrhages)
Osler’s nodules (painful red, raised lesions on palms and soles)
Murmur
Janeway lesions (non-tender, small macular lesions on palms and soles)
Anemia
Nail-bed hemorrhage
Emboli
What is the most common tumor of the adrenal medulla in adults? in children?
Adults: Pheochromocytoma (derived from chromaffin cells from neural crest)—rule of 10 (malignant, bilateral, extra-adrenal, calcify, in kids, familial)
Kids: neuroblastoma
Why should a “Hot T-bone stEAk” come to mind when someone asks you about interleukins?
Hot: IL-1 = fever
T-bone: IL-2= stimulates T cells
Bone: IL-3= stimulates bone marrow
“E” in steak: IL-4 = stimulates IgE production
“A” in steak: IL-5 = stimulates IgA production
Which phase of hepatic metabolism is lost first by geriatric pts?

Which phase is mediated by cytochrome p450?
Phase I: CYP 450; phase II: conjugation
Phase I is lost by geriatric patients first
What are the common causes of metabolic acidosis with an elevated anion gap?
Mnemonic: MUD PILES
Methanol, uremia, diabetic ketoacidosis; para-aldehyde, iron tablets/INH, lactic acidosis, ethylene glycol, salicylates (ex. Aspirin)
What cancer causes “punched-out” lytic bone lesions that can be seen on x-ray?
Multiple myeloma: cancer that arises from the marrow & produces large amounts of IgG or IgA (most common primary tumor arising within bone in the elderly)
Describe how the properties and clinical use of leuprolide can change depending on how it is administered.
GnRH analog w/ agonist properties when used in pulsatile fashion
Antagonist properties when used in continuous fashion
What are some of the complications associated with lung cancer?
Mnemonic: SPHERE
S: superior vena cava syndrome
P: pancoast tumor
H: Horner syndrome
E: endocrine (paraneoplastic)
R: recurrent laryngeal symptoms (hoarseness, etc.)
E: effusion (pleural, pericardial)
What are the irreversible enzymes of glycolysis?

What are the irreversible enzymes of gluconeogenesis?
Irreversible enzymes of glycolysis: phosphofructokinase 1, pyruvate kinase, glucokinase

Irreversible enzymes of gluconeogenesis: pyruvate carboxylase, PEP carboxykinase, fructose-1,6-bisphosphatase, glucose-6-phosphatase
In cases of hyperkalemia, what can be done to acutely shift potassium out of the serum and into cells in order to avoid cardiac arrhythmias?
Give insulin or a beta-adrenergic agonists
Induce alkalosis or hypo-osmolarity
Which vitamin is a cofactor for carboxylations?
Biotin (B7)
Which vitamin is converted to a cofactor used in transamination (ALT, AST)?
Vitamin B6 (pyridoxine) which is required for the synthesis of niacin from tryptophan
Which vitamin deficiency is detected in the Schilling test?
B12
What nerves innervate the tongue?
Anterior 2/3: taste=facial (chorda tympani), sensory=mandibular of trigeminal (V3)
Posterior 1/3: glossopharyneal does both
Muscles: hypoglossal