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300 Cards in this Set

  • Front
  • Back
What is the treatment of cardiogenic shock?
Vasopressor (Dobutamine)
What systemic diseases can cause nephritis syndrome?
DM
SLE
Amyloidosis
Hypoxemia + pulmonary edema + normal pulmonary capillary wedge pressure =
Acute respiratory distress syndrome
What disorder is present in a teenager with a history of theft, vandalism, and violence toward family pets?
Conduct disorder
Continuous machine-like murmur
Patent Ductus Arteriosis
What would you suspect in a woman with preeclampsia in the first trimester?
Hydatidiform mole
What CSF findings would you see in a case of subarachnoid hemorrhage?
Elevated CSF pressure
RBCs in 3+ tubes
Xanthochromia (after a few days)
What acid-base disturbance is commonly seen in pregnant women?
Respiratory alkalosis
A husband asks that his wife not be told about her recently discovered lung cancer -> What do you do?
Assess whether telling the patient will harm the patient, but in any case a relative cannot withhold information from a patient.
Does a case-control study measure incidence or prevalence?
Neither.
What is the first-line treatment for a growth hormone-secreting pituitary adenoma?
Transsphenoidal surgical resection
What are the indications for surgical repair of an abdominal aortic aneurysm?
Diameter > 5.5 cm
Rapidly enlarging
Symptomatic or ruptured
What characteristics of a nevus suggest that it may actually be a melanoma?
ABCD

Asymmetry
Border irregularity
Color variation
Diameter (if larger than a pencil eraser)
Low urine specific gravity in the presence of high serum osmolality -> What is the diagnosis?
Diabetes insipidus
What is the treatment of atrial fibrillation of unknown duration?
Rate control (beta-blockers, verapamil, digoxin)
Heparin + Warfarin
Which lung cancer is associated with SIADH?
Small cell lung cancer
What important side effects are common to many of the atypical antipsychotics?
Weight gain
DM Type 2
What is the most common location for an ectopic pregnancy?
Ampulla of fallopian tube
Uterine bleeding at 18 weeks' gestation + no products expelled + membranes ruptured + cervical os open = What diagnosis?
Inevitable abortion
ICU patient is awake and alert but cannot move anything but the eyes and eyelids. What is the diagnosis?
Locked-in syndrome
(Involving the Basilar artery)
What type of shock causes a decreased cardiac output, decreased PCWP, and decreased peripheral vascular resistance?
Septic shock
Anaphylactic shock
Neurogenic shock
What is the most common form of nephritic syndrome?
Membranous glomerulonephritis
What is the initial treatment for child presenting with acute asthma attack?
IV Steroids
Albuterol
Oxygen
What type of psychotherapy is used in treating phobias, obsessive-compulsive disorder (OCD), and panic disorder?
Cognitive behavioral therapy
What is the underlying cause of neonatal respiratory distress syndrome?
Surfactant deficiency (Lung immaturity)
What is the first test in the assessment of a woman presenting with secondary amenorrhea?
beta-hCG
What are the components of HELLP syndrome?
Hemolysis
Elevated LFTs
Low Platelets
What medication is used to diagnose symptomatic myasthenia gravis?
Edrophonium (Tinsilon test)
An 11-year old obese, African-American boy presents with sudden onset of limp. What is the most likely diagnosis, and what imaging studies would confirm this?
Slipped capital femoral epiphysis

Tests: X-Rays AP and frog-leg lateral
What organism is associated with dog or cat bites?
Pasturella multocida
How is polycythemia vera distinguishable from secondary polycythemia?
Both have elevated Hb, RBC mass, Hct

Polycythemia vera is not due to low oxygen saturation or elevated EPO. You will have low or normal EPO, O2 sat is normal.
What is the medical treatment for hepatic encephalopathy?
Lactulose
A young child presents in status epilepticus, but her parents refuse treatment on religious grounds. What do you do?
Treat anyways, seek court order after
What percentage of values fall within one standard deviation of the mean? Two SDs? Three SDs?
One SD: 68%
Two SDs: 95%
Three SDs: 99.7%
In which endocrine disorder might weight loss completely eliminate the need for medication?
Type 2 DM
PCOS
What rash is classically described as "dew drops on rose petals?"
Primary varicella (chicken pox)
What is the classic endocarditis prophylaxis regimen?
Oral surgery: Amoxicillin (before and after)
GI/GU procedures: Ampicillin + Gentamycin before, Amoxicillin after
Cafe-au-lait spots on skin
Neurofibromatosis Type I
What is the treatment for mild unconjugated hyperbilirubinemia? Severe unconjugated hyperbilirubinemia?
Mild unconjugated hyperbilirubinemia: Phototherapy

Severe unconjugated hyperbilirubinemia: Exchange transfusion
What number is needed on bacterial culture of a clean-catch specimen to diagnose a UTI?
100,000 (10^5) bacteria per ml
What is the classic ECG appearance in atrial flutter?
Saw-tooth pattern of P waves
A 60-year old obese patient presents with dirty, velvety patches on the back of the neck. What is the diagnosis and what is the initial work-up?
Acanthosis nigricans

Glucose to rule out DM, thorough H/P to look for signs of malignancy
What is the most common cause of hypothyroidism?
Hashimoto's thyroiditis
Which type of bias is introduced when screening detects a disease earlier and thus lengthens the time from diagnosis to death?
Lead-time bias
What are the exceptions to the requirement of informed consent?
Emergencies
Patients without decision making capacity
Patients that sign waivers to the right of informed consent
A 19 year old man presents with a palpable flank mass and hematuria. U/S shows bilateral enlarged kidneys with cysts. What brain anomaly is associated with this condition?
Berry aneurysm
What are the four main causes of microcytic anemia?
Iron deficiency anemia
Anemia of chronic disease
Thalassemias
Lead poisoning
What are four signs and symptoms of streptococcal pharyngitis?
Fever
Pharyngeal erythema
Tonsillar exudates
Lack of rhinorrhea
Lack of cough
In which region of the US is Lyme disease endemic?
American northeast
Which joints in the hand are affected in rheumatoid arthritis?
MCP and PIP
Xerostomia + parotid enlargement + xerophthalmia + anti-La antibodies =
Sjogren's syndrome
What are the most common causes of seizures in young adults (ages 18-35)?
Trauma
Alcohol withdrawal
Brain tumors
What is the most common cause of non-obstetric post-partum death?
Thromboembolic disease
Uterine bleeding at 18 week's gestation + no products expelled + cervical os closed. What is the diagnosis?
Threatened abortion
Which immunodeficiency presents with eczema, thrombocytopenia, and high levels of IgA?
Wiskott-Aldrich syndrome
Which defense mechanism is displayed when a woman calmly describes a gory murder in great detail?
Isolation
What is the treatment for mild, persistent asthma?
Albuterol + inhaled low dose corticosteroids
EKG with peaked T waves and widened QRS?
Hyperkalemia
What is the treatment for iron overdose?
Deferoxamine
What is the acceptable minimum urine output in a stable patients?
30cc/hour
What method is used to calculate fluid repletion in burn patients?
Parkland formula:
4 mL x kg (patient weight) x % body surface burned.
Salicylate ingestion results in what type of acid-base disorder?
Mixed Respiratory alkalosis + Metabolic acidosis with elevated anion gap
What medication is used most commonly to induce ovulation?
Clomiphene citrate
Pulsatile leuprolide
Pyschiatric condition which a person travels a long distance, takes a new name, and has no memory of his prior life.
Dissociative fugue
Which congenital infection might present with a "blueberry-muffin" rash?
Rubella
Which type of breast cancer increases the future risk of invasive carcinoma in both breasts?
Lobular carcinoma in situ
What are the classic symptoms of placenta previa?
Painless vaginal bleeding during 3rd trimester.
An active 14-year old boy has anterior knee pain. What is the most likely diagnosis?
Osgood-Schlatter disease
Joint aspirate reveals rhomboid-shaped, positively birefringent crystals. What is the diagnosis?
Pseudogout
What type of oral infection has branching rods when examined microscopically?
Actinomyces israeli
What is the next step in the evaluation of a patient with two consecutive Pap smears with atypical squamous cells of undetermined significance (ASCUS)?
Colposcopy with endocervical curetage
A 45-year old obese female with pruritis, clay-colored stools, and dark urine has an elevated alkaline phosphate and elevated bilirubin. What is the most likely cause?
Biliary tract obstruction
(ie.Gall stones)
What infection can cause diarrhea and pseudoappendicitis?
Yersinia enterocolitica
Which is more ethically unfavorable in a DNR patient: withdrawing life-sustaining care or withholding care?
Does not matter. Both are the same.
What is the most likely cause of acute lower GI bleeds in patients older than 40?
Diverticulosis
What is the most common underlying cause of pathologic fractures in elderly, thin women?
Osteoporosis
What is the causative agent in pityriasis versicolor?
Malassezia furfur
What is the cause of chest pain in a young patient that has angina at rest with ST-segment elevation but normal cardiac enzymes?
Prinzmetal's angina
Which hypercholesterolemia treatment causes flushing and pruritis?
Niacin
Target lesions with a red center, pale zone, and dark outer ring appearing on the palms and soles with a prodrome of malaise and myalgias.
Erythema multiforme
What autoimmune complication occurs 2-4 weeks after an MI?
Dressler's syndrome
(Fever, pericarditis, increased ESR)
What name is given to stress-related hair loss? What is the treatment?
Telogen Effluvium
Rx: Reassurance
What is the most common cause of Cushing's syndrome?
Exogenous steroid use

(2nd most common is ACTH secreting tumor = Cushing's disease)
What is the most likely cause of galactorrhea, impotence (or menstrual dysfunction), and decreased libido in a patient with a history of schizophrenia?
Anti-psychotic side effect: Dopamine antagonist (Haloperidol)
What ethical problem exists when a doctor refers a patient for an MRI at a facility he owns?
Conflict of interest
Patient presents with sudden onset of severe, diffuse abdominal pain. AXR reveals free air under the diaphragm. What is the next step in management?
Emergency laparotomy
What are the two most common foodborne bacterial GI tract infections in the US?
Salmonella
Campylobacter
What is the diagnostic test for hereditary spherocytosis?
Osmotic Fragility test
What bullous skin disease has a negative Nikolsky's sign?
Bullous pemphigoid
A 25 year old male presents with white plaques on his tongue and the back of his throat that scrape off with a tongue depressor. What is the diagnosis? What should he be screened for?
Oral Candidiasis (Thrush)
Screen for HIV
Young male with hip and back pain along with stiffness that improves with activity and worsens at rest. What is the most likely diagnosis?
Ankylosing Spondylitis
Cold water is flushed into a patient's ear, and the fast phase of the nystagmus is towards the opposite side. Where is the lesion?
No lesion. This is normal.
What findings would you expect to see in a post-term pregnancy beyond 42 weeks gestation?
Oligohydramnios
Passage of meconium in utero
Dry peeling skin
Placenta will be very mature with calcifications
What annual screening is recommended for women with strong family history of ovarian cancer?
CA 125
Transvaginal ultrasound
A one year old is able to cruise, use two-finger pincer grasp, babble, and imitate actions. What part of his development is delayed.
A 1 year old should be able to say a few words. His language is delayed.
Which defense mechanism is a pedophile that enters a monastery using?
Reaction formation
What are some of the causes of an exudative pleural effusion?
Cancer
TB
Bacterial infections
Pulmonary emboli
Pancreatitis
What would you expect with eosinophilic casts found in the urine?
Acute interstitial nephritis
(AKA Allergic interstitial nephritis)
What are the side effects of corticosteroids?
Cushingoid symptoms (weight gain, buffalo hump)
Osteoporosis
Immunosuppression
Acne
Insulin resistance
Thin skin
Mania
Insomnia
Cataracts
What is an acceptable urine output in a trauma patient?
50cc/hour
What is the treatment for ventricular fibrillation (VF)?
Immediate cardioversion (360 J) Epinephrine or Vasopressin
What skin blistering disease has a positive Nikolsky's sign?
Pemphigus vulgaris
What is the most common inherited cause of hypercoagulability?
Factor V Leiden
Which genetic disorder is associated with multiple fractures and is commonly mistaken for child abuse?
Osteogenesis imperfecta
What is the most common cause of bloody nipple discharge?
Intraductal papilloma
Which antibiotics should be avoided during pregnancy due to potential teratogenic effects?
Fluoroquinolones
Tetracyclines

Aminoglycosides, Sulfonamides (less concerning)
Antihistone antibodies
Drug induced Lupus
(ie. Hydralazine)
Infectious cause of aplastic crisis in sickle cell disease
Parvovirus B12
Tachycardia + wild fluctuations in BP + headache + diaphoresis + panic attacks?
Pheochromocytoma
What should always be done prior to LP?
Check for increased ICP (Check for papilledema)
What is the next step in the diagnosis of cholecystitis when U/S is equivocal?
HIDA scan
What is the clinical definition of HTN?
>140/90 for 3 separate visits at least 2 weeks apart
What are the most common causes of fever of unknown origin?
Infection
Cancer
Autoimmune diseases
What is the most feared complication of a scaphoid fracture?
Avascular necrosis
Albuminocytologic dissociation (increased protein in CSF with only modest increase in cell count)
Guillan-Barre
What two disorders should come to mind when a neonate has meconium ileus?
Cystic fibrosis
Hirshsprung disease
Immunodeficiency with a positive nitroblue tetrazolium test?
Chronic granulomatous disease
Pediatric patient with red "currant-jelly" stools?
Intussusception
A young female with amenorrhea, bradycardia, and abnormal body image.
Anorexia nervosa
What is the treatment for superior vena cava syndrome?
Radiation of lung tumor
Steroids
What statistical calculation looks at true positives and divides them by the number of patients with the disease?
Sensitivity
A 15-year old pregnant girl requires hospitalization for preeclampsia. Should her parents be informed?
No. Parental consent is not necessary for treating pregnant minors (nor for STDs, contraception)
A patient is unable to inspire completely due to pain during palpation of the RUQ. What is this sign? What is the diagnosis?
Murphy's sign
Acute cholecystitis
What is the reversal agent for heparin?
Protamine sulfate
What substances are known to cause hemolysis in patients with G6PD Deficiency?
Sulfa drugs
Fava beans
anti-malarials (primaquine)
High dose aspirin
Isoniazid
Nitrofurantoin
Dapsone
What medications can be given to a pregnant woman with cystitis?
Amoxicillin
Nitrofurantoin
1st, 2nd gen ceph
A patient presents with limb pain on passive movement, pallor, poikilothermia, paresthesias, paralysis, and pulselessness. What is the treatment?
Compartment syndrome:
Fasciotomy
What complication may arise from overly rapid correction of hyponatremia?
Central pontine myelinolysis
A 60 year old patient presents with an acute onset of broken speech. What type of aphasia is this? What lobe and vascular distribution has been affected? What is the first step in the workup?
Broca's aphasia
Dominant frontal lobe lesion, via the Middle Cerebral Artery
Workup requires CT scan to rule out hemorrhage
What are the most common primary sources of metastasis to the brain?
Lung, breast, melanoma, renal and GI tract cancers
What is the treatment for mastitis in a patient that is breast-feeding?
Continue breast feeding
Oral antibiotics
What characteristics favor carcinoma in an isolated pulmonary nodule?
New nodule or increasing size
No calcifications (or irregular calcifications)
History of smoking
Age > 45
Size > 2 cm
Irregular margins
In which disease would you find atrophy of the mammillary bodies?
Wernicke's encephalopathy
What term describes heavy bleeding during and between menstrual periods?
Menometrorrhagia
What is the most common type of tracheoesophageal fistula?
Blind proximal esophagus, distal esophagus connected to trachea
What is the treatment for Kawasaki disease in the acute phase?
High dose aspirin
IVIG
What is considered first-line pharmacotherapy for depression?
SSRIs
Which antidepressants are associated with hypertensive crisis? What substance can exacerbate this effect?
MAOIs
Tyramine
A 40 year old black female is found to have noncaseating granulomas of the lung and hypercalcemia. What is the diagnosis?
Sarcoidosis
In what disease might you find Curschmann's spirals (whorled mucous plugs)?
Asthma
Which type of renal tubular acidosis (RTA) is associated with abnormal H+ secretion and nephrolithiasis?
Type I
What are the causes of hypervolemic hyponatremia
CHF
Cirrhosis
Nephrotic syndrome
A burn patient presents with cherry-red flushed skin and coma. O2 saturation is normal, but carboxyhemoglobin is elevated. What is the treatment?
This is CO poisoning.

100% O2
Hyperbaric oxygen
What is the treatment for delirium tremens?
This is caused by alcohol withdrawal

Benzodiazepines (Chlordiazepoxide)
What is the most common cause of postpartum hemorrhage?
Uterine atony
Which drugs block transmission through the AV node?
Beta-blockers
Digoxin
CCBs
What skin lesion causes a pearly-colored papule with a translucent surface and telangiectasias?
Basal cell carcinoma
What type of infection causes honey-crusted lesions usually around the nose or mouth?
Impetigo (Staph aureus, Strep pyogenes)
What causes hypocalcemia, high phosphorous, and low PTH?
Hypoparathyroidism
What causes stones, bones, groans, and psychiatric overtones?
Hypercalcemia
Hyperparathyroidism
What is the first-line treatment for acute otitis media?
Amoxicillin 10 days
Does a cohort study identify incidence or prevalence?
Both
When can a physician refuse to continue treating a patient on the grounds of futility?
No rationale for treatment
When maximal intervention has failed
Treatment has not achieved goals of care
A violent patient with vertical and/or horizontal nystagmus has been exposed to what substance?
PCP
What diarrheal illness is associated with church picnics/mayonnaise?
Pre-formed Staphylococcus aureus toxins
What is a cause of congenital pure RBC aplasia?
Diamond-Blackfan anemia
What is the pentad of thrombotic thrombocytopenic purpura (TTP)
Thrombocytopenia
Hemolytic anemia
Uremia
Fever
Altered mental status
A patient that visited the SW US presents with fever, malaise, cough, and night sweats. What is the diagnosis and treatment?
Coccidioidomycosis

Rx: Fluconazole
Ring-enhancing brain lesion on CT with seizures
Brain Abscess

Toxoplasmosis
What are the classic physical findings in cases of endocarditis?
Fever
Roth spots
Osler nodes
Murmur
Janeway lesions
Anemia
Nail-bed (splinter) hemorrhages
Emboli
A 55 year old man has sudden onset of pain in his first metatarsophalangeal joint after a night of drinking red wine. What is the diagnosis, workup, and how can it be treated chronically?
Gout
Joint fluid aspiration shows needle shaped, negatively birefringent crystals
Rx: Allopurinol, colchicine, Probenicid
Patient with a history of lithium use presents with copious amounts of dilute urine
Nephrogenic diabetes insipidus
What is the most common pituitary tumor, and what is the treatment?
Prolactinoma

Dopamine agonists (bromocriptine)
A male with a testicular mass is found to have an elevated beta-hCG. What is the diagnosis?
Testicular choriocarcinoma
What are the cardinal movements of labor?
Engagement
Descent
Flexion
Internal rotation
Extension
External rotation
Expulsion
50 year old female smoker presents with hematuria. What do you suspect?
Bladder cancer
30 year old female African immigrant presents with hematuria. What do you suspect?
Schistosomiasis
What therapies are used in treating polycystic ovarian syndrome?
Weight loss
Metformin
Oral contraceptive pills (for estrogen regulation)
Spironolactone (for hirsutism)
What type of bone fracture is most likely to result from a fall on an outstretched hand?
Distal radius fracture (Colles fracture)
A two month old presents with projectile, nonbilious, projectile emesis. What is the first step in the management?
Pyloric stenosis

Check for and correct metabolic abnormalities
Diagnose with ultrasound
Surgery for repair
A 16 year old female has left arm paralysis after her boyfriend dies in a car crash. No medical cause is found. What is the diagnosis?
Conversion disorder
A patient presents to the ER after a MVA with hypertension, bradycardia, and abnormal respirations. After ABCs, what is the next step in management?
Cushing's triad of elevated ICP
- Raise head of bed
- Hyperventilate
- Mannitol
- Neurosurgery consult
A normalizing PCO2 in a patient having an asthma exacerbation may indicate what problem?
Fatigue and impending respiratory failure
A patient has dyspnea, hilar lymphadenopathy on CXR, and hypercalcemia. What is the diagnosis?
Sarcoidosis
Which type of renal tubule acidosis is associated with abnormal HCO3- and rickets?
RTA type II
Chvostek's and Trousseau's sign
Hypocalcemia
A young patient whose father died at age 30 in an MVA suddenly collapses and dies while exercising. What is the cause of death?
Hypertrophic obstructive cardiomyopathy
Gyn exam of a postmenopausal woman reveals inflammation and epithelial thinning of the anogenital area. What is the diagnosis?
Lichen sclerosis
An IV drug user has JVD and a holosystolic murmur at left sternal border. What is the treatment?
Tricuspid regurgitation

Vancomycin
Treat heart failure, replace tricuspid valve
What is the classic ECG finding in pericarditis?
Low voltage diffuse ST-segment elevation
What is the treatment for neuroleptic malignant syndrome?
Dantrolene
Dopamine agonist (Bromocriptine)
A child has flesh-colored, umbilicated lesions on face. What are these lesions, and where do they appear in adults?
Molloscum contagiosum

Adults: Found in genital, perianal regions
Which medication is used more than any other in the treatment of Parkinson's?
Levadopa with carbidopa
What diagnostic test differentiates central from nephrogenic diabetes insipidus?
Administer DDAVP
Measure urine osmolality
A postop patient with significant pain presents with hyponatremia and normal volume status. What is the diagnosis?
SIADH due to stress
An elderly female presents with pain and stiffness of the shoulders and hips. She cannot lift her arms above her head. Lab shows an elevated ESR. What is the diagnosis?
Polymyalgia rheumatica
A child presents with oliguria, petechia, and jaundice following an illness with bloody diarrhea. What is the most likely diagnosis and infectious cause?
Hemolytic Uremic Syndrome
E. coli 0157:H7
An 11 year old boy presents with fever, weight loss, and night sweats. Radiology reveals an anterior mediastinal mass. What do you suspect? What is the patient was 30 years old?
11 year old: Non-Hodgkin's lymphoma

30 year old: Hodgkin's lymphoma
What prophylactic medication is indicated in an HIV patient with a CD4 less than 100?
TMP-SMX, Dapsone, Pentamidine (Toxoplasmosis, PCP)
Azithromycin (or Clarithromycin) for MAC
What is the most common testicular cancer?
Seminoma
A child presents with palpable purpura on the legs, abdominal pain, and arthritic pain in numerous joints. What is the diagnosis and treatment?
Henoch-Schonlein Purpura

Rx: Self-limited
Steroids for severe GI symptoms
Anticentromere antibodies
CREST scleroderma
Hyperphagia, hyperorality, hyperdocility, and hypersexuality
Kluver-bucy syndrome

Bilateral amygdala lesion
After a minor car accident, a woman wears a neck brace and requests permanent disability. What is the most likely diagnosis?
Malingering
What medication is given to accelerate fetal lung maturity? For how long is it given? At what gestational age is it no longer necessary?
IV Betamethasone or Dexamethasone

Given for 48 hours
Gestational age < 34 weeks
Patients with silicosis are at higher risk for what type of infection?
TB
A patient has exophthalmos, pretibial myxedema, and a decreased TSH. What is the diagnosis?
Graves disease
PFTs show decreased FEV1/FVC. What is the diagnosis?
Obstructive lung disease (Asthma, COPD, Emphysema)
A postmenopausal female presents with vaginal bleeding for the last 5 days. What is the next step?
Endometrial biopsy for suspected endometrial hyperplasia or carcinoma
Which type of lung cancer is associated with hypercalcemia?
Squamous cell (PTHrP secretion)
What does a fall in systolic BP of > 10 mmHG with inspiration indicate?
Pulsus paradoxus

Cardiac tamponade, Hyperinflation disorders (COPD, asthma)
What laparoscopic findings can be seen in endometriosis?
Chocolate cysts
Powder burn lesions
Hypertension + hypernatremia + hypokalemia + metabolic alkalosis. What is the diagnosis?
Hyperaldosteronism (Conn's or bilateral adrenal hyperplasia)
What is the LDL goal in a patient with diabetes?
LDL < 100
Any history of vessel disease LDL < 70
An 8 year old child was in a motor vehicle accident and now requires emergency blood transfusion. Her parents are not present, but the child states she is a Jehovah's witness. What do you do?
Treat anyways
Court order later
A 25 year old male presents with pain and watery diarrhea after meals. Exam shows fistulas between the bowel and skin and nodular lesions on his tibias. What is the diagnosis?
Crohn's disease
A 40 year old female presents with a discrete area of complete hair loss on the scalp that has worsened over weeks. What is the treatment?
Alopecia arreata

Observation (resolves on its own)
Intralesional steroids
CSF analysis shows low glucose, elevated neutrophils, and gram positive diplococci. What is the diagnosis?
Streptococcus pneumonia meningitis
What are the characteristic findings in tertiary syphilis?
Tabes dorsalis
Positive Romberg sign
Loss of proprioception
Gamut formation
Argyl-Robertson pupil
Aortitis (tree barking of aorta)
Aneurysm of aortic root
A young child presents with thigh muscle weakness, a waddling gait, and pronounced calf muscles. What is the diagnosis?
Duchennes Muscular dystrophy
A female who was born in breech position is found to have asymmetric inguinal and gluteal skin folds on her newborn exam. What is the diagnosis and treatment?
Developmental dysplasia of the hip

Rx: Pavlik harness
Head injury -> initial altered mental status -> resolution of mental status for a few hours -> now with reemerging altered mental status. What is the diagnosis, underlying injury, and treatment?
Epidural hematoma

Rupture of middle meningial artery

Neurosurgical evacuation
What medication is given for seizure prophylaxis in sever preeclampsia?
Magnesium sulfate
What is the cause of erythroblastosis fetalis?
Maternal antibodies against fetal Rh+ RBCs
Describe the treatment of hypertension in cases of pheochromocytoma
Alpha antagonist (phenoxybenzamine, phentolamine) FIRST

Beta-blockers after
A 7 year old boy presents with hemarthrosis. Lab-work shows increased PTT and normal PT and bleeding time. What is the diagnosis and treatment?
Hemophila A or B

Rx: Supplement with deficient factors
Desmopressin (Hemophilia A)
A tall, white male presents with shortness of breath. What diagnosis o you suspect? What is the treatment?
Spontaneous pneumothorax

Spontaneous regression
Pneumothorax > 15% requires chest tube placement
A 22 year old male has 4 months social withdrawal, worsening grades, decreased emotional expression, and concrete thinking. What is the diagnosis?
Schizophreniform
Honeycomb pattern on CT scan of the chest. What is the diagnosis and treatment?
Diffuse interstitial pulmonary fibrosis

Steroids + azathioprine (or Cyclophosphamide) + N-acetylcysteine
A young child has loss of the red light reflex. What is the diagnosis?
Retinoblastoma
What is the first-line treatment for moderate hypercalcemia?
IV Hydration
Loop diuretics
A 45-year old male presents with acute-onset flank pain and hematuria. What is the most likely etiology?
Nephrolithiasis
What test is used to rule out urethral injury?
Retrograde cystourethrogram
A 75 year old man presents with fatigue, lymphandeopathy, splenomegaly, and isolated lymphocytosis. What diagnosis do you suspect?
Chronic Lymphocytic Leukemia
Meningitis is diagnosed in a neonate. What are the most likely organisms, and what is the empiric treatment?
Group B strep
Listeria
E. coli

Ampicillin + Gentamycin
What pathology causes an onion-skin appearance of the bone on x-ray?
Ewing's sarcoma
Which skin cancer classically presents with varying degrees of scaling or ulcerations?
Squamous cell carcinoma
What is the treatment for the premalignant lesion from sun exposure that can lead to squamous cell skin cancer?
Actinic keratosis

5-FU or cryoablation
What is the general treatment of DKA?
IV Fluids
Insulin + dextrose
Electrolyte balance (Potassium, Bicarbonate, Magnesium, Phosphate)
A patient presents with weakness, nausea, vomiting, weight loss, and new skin pigmentation. Labs show hyponatremia and hyperkalemia. What is the treatment?
Addison's disease

Glucocorticoids and mineralcorticoids (Fludrocortisone)
What diagnosis would you consider in a patient with sacroilitis?
Ankylosing spondylitis
A child presents with a midline neck mass. What do you suspect?
Thyroglossal duct cyst
A child presents with a lateral neck mass. What do you suspect?
Brachial cleft cyst
What is the medical treatment for inflammatory bowel disease?
5-ASA +/- Sulfasalazine
Steroids
What is the difference between Mallory-Weiss and Boerhaave tears?
Mallory-Weiss is a superficial tear in the esophagus.

Boerhaave is a perforated esophagus. This is life threatening.
What is the treatment for TTP?
Plasmapharesis
Steroids
Which of the following are elevated in DIC: fibrin split products, D-dimer, fibrinogen, platelets, and Hct?
Fibrin split products, D-dimer are increased

Platelets, Hct, fibrinogen are decreased
What EKG finding is a/w hypothermia?
J wave
What infection is classically a/w cold agglutinins?
Mycoplasma pneumoniae
What are the signs suggesting radial nerve damage with a humeral fracture?
Wrist drop
Loss of thumb abduction
What is the first-line treatment for pediculosis pubis and pediculosis capitis?
Permethrin
Which immunodeficiency would you suspect in a patient with recurrent infections, thrombocytopenia, and eczema?
Wiskott-Aldrich syndrome
What causes a child to have mental retardation, microcephaly, microphthalmia, short palpebral fissures, midfacial hypoplasia, and cardiac defects?
Fetal alcohol syndrome
An 18 year old female with no history of abnormal pap smears now has a first time ASCUS pap. How should this be managed?
Re pap smear in 12 months.
What are the management options of a first time ASCUS pap in a non-adolescent?
1. Reflex HPV
Low risk: Re pap in 6-12 months
High risk: Colposcopy

2. Re pap in 6 months

3. Colposcopy
What is the treatment for a clavicle fracture?
Conservative management
If at birth, do not treat.

Figure of eight or sling
A 40 year old female has persistent erythema on her nose and cheeks and recurrent facial flushing especially with alcohol and spicy foods. What is the diagnosis?
Rosecea
A patient with cirrhosis presents again to the ER to have his ascites drained. Analysis of the ascites fluid reveals an absolute neutrophil count greater than 250 cells/mm3. What is the diagnosis?
Spontaneous bacterial peritonitis
Otoscopy in a child presenting with acute onset of ear pain reveals large, reddish vesicles on the TM. What is the diagnosis, typical organism, and treatment?
Bullous myringitis
Mycoplasma
Rx: Macrolides
What is the treatment for a pilonidal cyst?
Incision and drainage
What is the treatment for a rectal fistula?
Fistulotomy
A patient on isotretinoin for acne begins to develop daily, persistent, pulsatile headaches. Exam reveals papilledema. What is the diagnosis?
Pseudotumor cerebri caused by Tetracycline drug interaction
An 18 year old male is found to have a systolic heart murmur heard at the apex and left lower sternal border that increases in intensity while standing after squatting. What diagnosis do you suspect?
Hypertrophic obstructive cardiomyopathy
What disorder classically presents with the triad of cognitive impairment, urinary incontinence, and abnormal gait?
Normal pressure hydrocephalus
What is the underlying cause of late fetal decelerations on contraction stress test?
Utero-Placental insufficiency
A middle-aged man presents for knee pain and x-ray reveals bilateral calcifications of the articular cartilage. What is the treatment?
Pseudogout

Colchicine and NSAIDs
What is the next step in the management of a positive PPD?
Chest X-ray
A 25 year old male is diagnosed with a solid testicular mass by ultrasound. What is the next step in the management?
Orchiectomy of that testicle
A teenage on antibiotics for acne presents with a severe sunburn. What antibiotic is he most likely taking?
Tetracycline
What is the next step in the management of a female with poor uterine tone after delivery of the placenta?
Uterine massage
Oxytocin
What is Beck's triad for cardiac tamponade?
Elevated JVP
Distant heart sounds
Hypotension
What lab findings are diagnostic of Hashimoto's thyroiditis?
Increased TSH
Decreased T4
Anti-microsomal antibodies
If you want to know if maternal age affects infant mortality rate but most of the variation in infant mortality is predicted by socioeconomic status, then socioeconomic status is a _____.
Confounding variable
What are the 3 reasons for involuntary psychiatric hospitalization?
Danger to self
Danger to others
Patient is gravely disabled
What is Charcot's triad in cases of gallbladder disease?
Charcot's triad for ascending cholangitis

RUQ pain
Jaundice
Fever/chills
What is the treatment for ITP in children?
Usually resolves spontaneously

IVIG
Corticosteroids
What infection causes aplastic crisis in sickle cell disease?
Parvovirus B12
Elderly male complains of bony pain and adds that his favorite hat no longer fits.
Paget's disease
What test is used in the tenth week of gestation to screen for chromosomal abnormalities?
Chorionic villus sampling
What is the cause of secondary amenorrhea in a patient with normal prolactin + no response to estrogen-progesterone challenge + a history of D&C?
Asherman's syndrome
What causes a crescent-shaped hyperdensity on CT scan that does not cross the midline?
Subdural hematoma
Most common pathogen causing croup
Parainfluenza virus
What causes a transudative pleural effusion?
CHF
Liver or kidney disease
Protein-losing enteropathy
Immunodeficiency with doughy skin
Job's syndrome (Hyper IgE syndrome)
What is the treatment for opioid overdose?
Naloxone, naltrexone
What is the treatment for septic shock?
IV fluids
Antibiotics
Norepinephrine (Pressor)
Most serious side effect of clozapine?
Agranulocytosis
What are the 5 basic criteria for metabolic syndrome?
Abdominal obesity
Insulin resistance
High TG
Low HDL
Hypertension
What type of bias is present when a clinician is aware of the type of treatment his patient has received?
Observer bias
Sentinel loop on abdominal x-ray
Acute pancreatitis
What would you suspect in an ER patient with blood in the urethral meatus or a high-riding prostate?
Urethral injury
Bladder injury
What type of acute renal failure would you suspect in a patient with FENa < 1%?
Prerenal failure
What are the protein and LDH criteria for an exudative effusion?
Pleural protein to serum protein ratio > 0.5

Pleural LDH to serum LDH > 0.6
What is the cause of muscle rigidity, fever, and rhabdomyolysis in a schizophrenic patient?
Neuroleptic malignant syndrome
What is the cause of bilious emesis in a newborn within hours after the first feeding?
Duodenal atresia
A 60 year old woman leaks urine when laughing or coughing. What are her nonsurgical options?
Stress incontinence
Kegel exercises
Estrogen (oral or cream)
Pesary
What are the most common causes of seizures in children aged 2-10?
Febrile seizure
Infections
Trauma
Idiopathic
Positive p-ANCA
Pauci-immune glomerulonephritis
Microscopic polyangitis
Churg-strauss syndrome
What organism is known for causing infection in burn victims?
Pseudomonas
What is the most common cause of HTN in young women?
Oral contraceptive pills
A patient presents with a painless, pruritic papule with regional lymphadenopathy that evolves over 7-10 days into a necrotic ulcer with a black eschar. What is the diagnosis and treatment?
Cutaneous anthrax
Penicillin V or G
Ampicillin
Doxycycline
What is the late, life-threatening complication of chronic myelogenous leukemia (CML)?
Blast crisis: Fever, bone pain, splenomegaly, pancytopenia
Which hernia carries the highest risk of incarceration: indirect, direct, or femoral?
Femoral hernia
What cause of aplastic anemia is associated with thumb abnormalities, diffuse hypo- or hyperpigmentation, cafe-au-lait spots, and short stature?
Fanconi's anemia
What biostatistic calculation looks at individuals with and without a disease and determines the likelihood of exposure to a risk factor?
Odd's ratio
Which antidiabetic agent is associated with lactic acidosis?
Metformin
What is "cradle cap" and what is the treatment?
Seborrheic dermatitis

Rx: Selenium sulfide shampoo, topical antifungals
What diseases causes glomerulonephritis with deafness?
Alport's syndrome
What is the preferred diagnostic test for a pulmonary embolism?
CT w/ IV contrast

If unavailable: V/Q scan
What rash presents with herald-patch followed by a Christmas-tree pattern?
Pityriasis rosea