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34 Cards in this Set
- Front
- Back
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What are the neurotransmitter abnormalities for the following disorders:
anxiety = depression = Mania = Alzheimer's = Huntington's = Schizophrenia = Parkinson's = |
(+) = increased / (--) = decreased
anxiety = (+)NE, (--)Gaba, (--)5ht depression = (--) NE, (--)DA, (--) 5ht Mania = (+) NE, (+) 5ht Alzheimer's = (--) ACh Huntington's = (--) ACh, (--) Gaba Schizophrenia = (+) DA Parkinson's = (+) ACh, (--) DA |
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What are the general functions of:
NE 5ht DA ACh Gaba |
NE - Energy
5ht - Feel good DA - Thoughts, Movements ACh - Memory Gaba - Inhibitions |
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At what point does greif/berevement become pathological?
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Clinically depressed (for at least 2 weeks) after 2 months of loss
Not better at 6 mo Hopelessness, Helplessness, Worthlessness, Guilt, or thoughts of Si |
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What medical conditions cause severe depression?
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Hypothyroidism
Hyperparathyroidism Stroke of ACA Brain tumors Pancreatic Cancer Parkinson's dz |
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How are the TX's of the following linked to depression?
HTN in pregnancy Nausea Viral Hepatitis Autoimmune Dzs |
HTN in pregnancy - methydopa
Nausea - metoclopramide, prochlorperazine Viral Hepatitis - Alpha- Interferon Autoimmune Dzs - Glucocorticoids |
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What is the SAD PERSONS scale?
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Risk of Si. 7-10pts = hospitalization
SEX (male); AGE (outside 19-45); Depression; Prior attempts; Etoh/drugs; Rational thought (psychosis); Support (social); Organized plan; No spouse; Sickness (other medical px) |
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What are the symptoms of atypical depression?
Tx? |
Sleepy, Lazy, Hungry, Sensitive
Hypersomnia, Psychomotor retardation, Hyperphagia, Hypersensitive to rejection Tx= MAOIs : Phenylzine, Tranylcypromine, Selegeline |
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What is the TX for serotonin syndrome?
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TX for Serotonin Syndrome
1) stop Rx 2) BENZOS for agitation 3) if benzos fail, use CIPROHEPTADINE 4) if temp >41.1 paralyze and tube the pt |
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What are the two worst offenders for Serotonin Withdrawal Syndrome?
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Paroxitine (paxil)
Venlafaxine (effexor) |
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What do you need to consider when giving a TCA to a child?
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TCA's cause cardiac effects
Consider heart dz, EKG, Hx of syncope |
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What are the important s/e of TCAs and how should TCA overdose be managed?
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1) Activated charcoal (Anticholinergic sx) opposite of dumbells))
2) Cardiotox (if QRS>100ms give NaHCO3) 3) CNStox (Seizures- give Benzos) [Never give phenytoin] TCA: Imi Nor Ami Des Clo Dox |
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What is the time frame that seperates Acute Stress Disorder from PTSD?
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4 weeks
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The first line TX option for PTSD is _(drug class, 2 ex)_. Then __(drug class, 2 ex)__. Nightmares and sleep is improved with __(drug class, ex).
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1) SSRI: Fluvox, Fluox, Citalopram, Escitalopram, Paroxetine, Sertraline
2) Mood stabilizers like Valproic acid, Carbamazepine 3) Alpha Blockers like Prazosin |
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What's the Schiz?
Schizotypal = Schizophrenia = Schizoaffective = Schizoid = Schizophreniform = Breif Psychotic disorder = |
Schizotypal = personality disorder, dresses strange
Schizophrenia = > 6mo, affects work and social Schizoaffective = schizophrenia w/ mood disorder, never psychotic when not depressed Schizoid = personality disorder, schizoids avoid Schizophreniform = <6mo of schizophrenia Breif Psychotic disorder = <1mo |
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What defense mechanism is used in the following d/o?
Paranoid Borderline Histrionic OCPD |
Paranoid --- PROJECTION
Borderline---SPLITTING Histrionic--- REPRESSION OCPD---ISOLATION |
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The best treatment for alcoholics is ______, but 4 Rx are also used to prevent relapse in recovering alcoholics, what are they?
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Alcoholics Annonymous
Disulfram Topirimate Naltrexone Acamprosate |
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What is the Tx for a PCP pt with a temp of >40.5C?
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Vercuronium paralysis to prevent hyperthermia d/t muscle heat
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Intoxication/ Withdraw from what causes...
Severe depression, headache, fatigue, Insomnia/ Hypersomnia, hunger? |
Cocaine/ Amphetamine withdraw
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Intoxication/ Withdraw from what causes...
Pinpoint pupils, Decreased LOC, Depressed respirations? |
Opioid intox -
Classic triad of Pinpoint pupils, Decreased LOC, Depressed respirations |
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Intoxication/ Withdraw from what causes...
Belligerence, impulsiveness, nystagmus, homocidal ideations, psychosis |
PCP intox
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Intoxication/ Withdraw from what causes...
Headache, anxiety/ depression, weight gain |
Nicotine/ Caffiene withdraw
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Intoxication/ Withdraw from what causes...
Rebound anxiety, tremors, seizures, life threatening? |
Withdraw from Etoh, benzos, barbiturates
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Intoxication/ Withdraw from what causes...
Anxiety, piloerection, yawning, fever, rhinorrhea, nausea, diarrea |
Opioid withdraw
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What criteria must be met to Dx a child with ADHD?
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SIX symptoms in at least TWO settings, diagnosed before are SEVEN.
Do not treat children for ADHD before age SIX |
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What co-morbidities are common in children with ADHD?
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Oppositional defiant disorder
Conduct d/o Learning disabilities Depression Bipolar d/o Anxiety d/o |
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What is the Mnemonic for cluster A, B, and C personality d/o?
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"SPS-BAHN-DOA!"
Schizoid, Paranoid, Schizotypal Borderline, Antisocial, Histrionic, Narcissistic Dependent, OCPD, Avoidant |
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What is the Mnemonic for the Sxs of Depression
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"SIG-E-CAPS"
Sleep, Interest, Guilt Energy Concentration, Appetite, Pyschomotor, Suicide |
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What is the Mnemonic for the Sxs of Mania?
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"DIG FAST"
Distractibility, Insomnia, Grandiosity Flight of ideas, Activity, Speach (pressured), Taking risks |
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Whats a good way to induce a manic episode in a bipolar patient?
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Give an antidepressant when they are not taking a mood stabilizer, that should pretty much put them through the roof.
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How does Adjustment Disorder differ from Berevement?
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Adjustment disorder = Altered ability to fxn, not do to a death.
Berevement = do to a death, no change in ability to function |
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Panic disorder is increased in pts with _______.
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Mitral valve prolapse, and agoriphobia.
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How do you differentiate Conversion d/o and Pain d/o from Fibromyalgia?
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Conversion and Pain d/o are related to a stressful event.
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_______ or _______ can worsen the symptoms of delerium and should never be used in the treatment of dementia/ delerium related agression
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Benzodiazepines, Anticholinergics
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Label the Axis
I II III IV V |
I- mood and anxiety
II - Personality and MR III - medical cond't IV - social and environmental V - global assessment |
