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13 Cards in this Set
- Front
- Back
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What lab distinguishes true precocious puberty from pseudoprecocious puberty?
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True (central) precocious puberty: LH and FSH elevated. When give GnRH it further increases it.
Pseudoprecocious Puberty: Low FSH and LH. No response to GnRH |
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What is the definition of precocious puberty?
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Female: pubertal changes younger than 8.
Males: younger than 9 |
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What are some causes of pseudoprecocious puberty?
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Pseudoprecocious Puberty:
1) exogenous 2) adrenal tumors 3) CAH 4) hormone secreting tumors (sertoli Leydin, granulosa theca) 5) McCune Albright |
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What is definition of premature ovarian failure
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Absense of menses for at least 6 months younger than FORTY (40).
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What hormone is associated with an increase in basal body temp? How is basal body temperature increase associated with ovulation?
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Progesterone.
Q: How is basal body temperature increase associated with ovulation? A: 24 hours prior to ovulation. |
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What are 4 different options for emergency contraception?
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1) estradiol/progesterone pill (take 4-5x normal) all within 24 hours
2) progesterone alone - Levonorgestrel ("plan B") 3) copper IUD 4) anti progesterone drug, mifiperstone, RU-486 |
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What are contraindications for OCP use
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What are contraindications for OCP use:
1) pregnancy 2) history of thromboembolism 3) inherited thrombophilia hypercoagulability, like factor V Leiden mutation 4) history of estrogen dependant tumor (like endometrial/breast cancer) 5) smoker over 35 6) hepatic disease 7) coronary artery disease |
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What medication decrease the effectivness of OCP?
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What medication decrease the effectivness of OCP?
1) rifampin 2) griseofulvin 3) anti epileptic drugs 4) st john's wort |
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Define primary amenorrhea.
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Absense of period by age 16 with secondary sex characteristics
OR Absense of period and secondary sex characteristics by age 13 |
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What is the first step in any work up for amenorrhea?
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What is the first step in any work up for amenorrhea?
beta-hCG |
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Workup for secondary amenorrhea?
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Workup for secondary amenorrhea?
1) b-hcg 2) prolactin 3) TSH 4) FSH 5) testosterone, DHEAS (adrenal source) 6) Progestin withdrawal test |
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HYQ: Primary amenorrhea + absent secondary sexual characterisitcs + anosmia
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Kallman syndrome (congential absense of GnRH secretion)
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HYQ: What is the initial step in management of a woman presenting with secondary amenorrhea and new galactorrhea when the b hcg is negative?
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TSH level to r/o hyptothyroidism.
Check prolactin as well |
