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16 Cards in this Set

  • Front
  • Back
diabetic drug :lactic acidosis is side effect
metformin
diabetic drug : most common isde effect is hypoglycemia
sulfonylureas
diabetic drug : often used in combo with any of the other oral agents
metformin
diabetic drug : also helps lower triglycerides and LDL cholesterol levels
metformin
diabetic drug : not safe to used in heaptic dysfunction of CHF
TZD and metformin
diabetic drug : should not be used in patient with elevated serum creatine
metformin
should not be used in pts with liver cirrhosis, elevated serm creatinine or inflammatory bowel disease
alpha glucosidose inhbitors
diabetic drug : hepatic serum transaminase levels should be carefully monitored
metformin and TZD
diabetic drug : not associated with weight gain and often used in overweight pts
metformin
diabetic drug :metabolized by liver, excellent choice in patenst with renal disease
TZD
diabetic drug : primarily effect postprandial hyperglycemia
alpha glucosidase inhibitors
diabetic drug : MOA closes K channel on beta cells to increase Ca in cell and cause insulin release
sulfonylureas
diabetic drug : MOA inhibits alphaglucosidase at intestinal brush border
alpha glucosidase inhibitors
diabetic drug : MOA- agonist at PPAR gamma receptors to improve target cells response to insulin
TZD
what enzyme makes sorbitol
aldose reductase
where is there no sorbitol dehyrogenase
schwann, lens, retina, and kidney