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16 Cards in this Set
- Front
- Back
diabetic drug :lactic acidosis is side effect
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metformin
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diabetic drug : most common isde effect is hypoglycemia
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sulfonylureas
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diabetic drug : often used in combo with any of the other oral agents
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metformin
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diabetic drug : also helps lower triglycerides and LDL cholesterol levels
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metformin
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diabetic drug : not safe to used in heaptic dysfunction of CHF
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TZD and metformin
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diabetic drug : should not be used in patient with elevated serum creatine
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metformin
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should not be used in pts with liver cirrhosis, elevated serm creatinine or inflammatory bowel disease
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alpha glucosidose inhbitors
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diabetic drug : hepatic serum transaminase levels should be carefully monitored
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metformin and TZD
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diabetic drug : not associated with weight gain and often used in overweight pts
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metformin
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diabetic drug :metabolized by liver, excellent choice in patenst with renal disease
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TZD
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diabetic drug : primarily effect postprandial hyperglycemia
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alpha glucosidase inhibitors
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diabetic drug : MOA closes K channel on beta cells to increase Ca in cell and cause insulin release
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sulfonylureas
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diabetic drug : MOA inhibits alphaglucosidase at intestinal brush border
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alpha glucosidase inhibitors
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diabetic drug : MOA- agonist at PPAR gamma receptors to improve target cells response to insulin
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TZD
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what enzyme makes sorbitol
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aldose reductase
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where is there no sorbitol dehyrogenase
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schwann, lens, retina, and kidney
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