Dit Day 8

Front 1

chorioretinitis, hydrocephalus, and intracranial calcifications. Dx?

Back 1

toxoplasma

Front 2

newborn w/ PDA, cataracts, and deafness

Back 2

rubella

Front 3

what is the presenation of CMV as a congenital TORCH infection?

Back 3

unilateral hearing loss, seizures

Front 4

which abx has SE:

1) tendonitis
2) gray baby syndrome
3) cartilage damage in children

Back 4

1) fluoroquinolone
2) chloramphenicol
3) fluoroquinolone

Front 5

which abx is used for tx for gram neg rods in pts w/ renal insufficiency

Back 5

aztreonam

Front 6

what neoplasms are a/w tuberous sclerosis?

Back 6

cardiac rhabdomyoma, angiomyolipoma, astrocytoma

Front 7

what neoplasms are a/w ataxia telangectasia?

Back 7

leukemia, lymphoma

Front 8

which neoplams is a/w naphthalene?

Back 8

bladder transitional carcinoma

Front 9

which neoplasm(s) is a/w arsenic

Back 9

SCC of skin, angiosarcoma (liver)

Front 10

which neoplasms are a/w EBV

Back 10

lymphoma, oral hairy leukoplakia

Front 11

which tumor marker would you use to follow astrocytomas?

Back 11

S-100

Front 12

what neoplasm is most commonly responsible for paraneoplastic syndrome where:

1) ACTH --> Cushing's syndrome
2) erythropoietin --> polycythemia
3) ADH --> SIADH

Back 12

1) small cell lung CA
2) renal cell CA, hepatocellular CA, hemangioblastoma, pheochromocytoma
3) small cell lung CA

Front 13

which anticancer drug:
1) alkylates DNA, toxicity --> pulm fibrosis
2) fragments DNA, toxicity --> pulm firbrosis

Back 13

1) busulfan
2) bleomycin

Front 14

which anticancer drug:

1) blocks purine synthesis, metabolized by xanthine oxidase
2) cross-links DNA, nephrotoxic, ototoxic

Back 14

1) 6-mercaptopurine
2) cisplatin

Front 15

which anticancer drug:

1) nitrogen mustard, alkylates DNA (electrophil that binds DNA)
2) prevents tubulin disassembly

Back 15

1) cyclophosphamide
2) paclitaxel, other taxols

Front 16

which anticancer drug:

1) DNA alkylating agents used in brain cancer
2) prevents tubulin assembly

Back 16

1) nitrosurea
2) vincristine/vinblastine

Front 17

which anticancer drug:

1) mechanism similar to antivirals acyclovir
2) inhibitor of PRPP synthetase

Back 17

1) cytarabine
2) 6-mercaptopurine

Front 18

which 2 anticancer drugs cause free radical induced DNA strand breakage

Back 18

bleomycin, doxorubicin/daunorubicin

Front 19

which anticancer drug:

1) treatment for choriocarcinoma
2) treatment for AML

Back 19

1) methotrexate, vincristine/vinblastine
2) cytarabine

Front 20

which anticancer drugs are used for the treatment of testicular cancer (3)?

Back 20

"Eradicate Ball Cancer"

etoposide, bleomycin, cisplatin

Front 21

anticancer drug used for tx of childhood tumors (Ewing sarcoma, Wilm's tumor, rhabdomyosarcoma)

Back 21

dACTinomycin
("Children ACT out")

Front 22

which anticancer drug:

1) inhibits ribonucleotide reductase
2) inhibits thymidilate synthase --> decreased nucleotide synthesis

Back 22

1) hydroxyurea
2) 5-fluorouracil (5-FU)

Front 23

what are the potential side effects of prednisone use? (10)

Back 23

HTN, hyperglycemia, peptic ulcers, acne, cushingoid symptoms, psychosis, insomnia, cataracts, immunosuppression, osteoporosis

Front 24

which parts of the thalamus:

1) comunications w/ prefrontal cortex
2) basal ganglia --> prefrontal, premotor, and orbital cortices

Back 24

1) medial dorsal
2) ventral anterior

Front 25

which part of the thalamus:

1) cerebellum (dentate nucleus) and basal ganglia --> motor cortex
2) mamillothalamic tract --> cingulate gyrus (part of Papez circuit)

Back 25

1) ventrolateral (VL)
2) anterior nucleus

Front 26

which part of thalamus:

1) memory loss results if destroyed
2) integration of visual, auditory, and somesthetic input

Back 26

1) medial dorsal
2) pulvinar nucleus

Front 27

which primary bone tumor:

1) most common malignant primary bone tumore of childrens
2) of adults?
3) most common benign bone tumore

Back 27

1) osteosarcoma
2) multiple myeloma
3) osteochondroma

Front 28

which primary bone tumor:

1)11;22 translocation
2) soap-bubble appearance on x-ray

Back 28

1) Ewing's sarcoma
2) giant cell tumor

Front 29

which primary bone tumor:

1) onion-skin appearance of bone
2) may actualliy be a hamartoma
3) assocatied w/ Gardner's syndrome

Back 29

1) ewing's sarcoma
2) osteochondroma
3) osteoma

Front 30

what tumor is a/w:

1) bcl-2
2) c-myc
3) abl

Back 30

1) follicular lymphoma
2) burkitt's lymphoma
3) CML (bcr-abl fusion protein)

Front 31

what do these tumor markers monitor for:

1) alpha-fetoprotein
2) beta-hCG

Back 31

1) hepatocellular carcinoma; nonseminomatous germ cell tumors of the testis (yolk sac tumor)
2) hydatiform mole, choriocarcinoma

Front 32

what do these tumor markers monitor?

1) s-100
2) TRAP

Back 32

1) astrocytoma, melanoma, neural tumors (schwannoma)
2) hairy cell leukemia (B cell neoplasm)