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31 Cards in this Set

  • Front
  • Back
name the specific antidotes:

salicylates
NaHCO3 (alkalinize urine)
Amphetamines
NH4Cl (acidify urine)
antimuscarinic, anticholinergic agents
physostigmine
beta blockers
glucagon
digitalis
stop dig, normalize K, lidocaine, anti-dig Fab fragments, Mg
lead
CaEDTA, succimer
mercury
diMERCaprol
copper
penicillamine
cyanide (may be 2/2 nitroprusside use to dec severely elevated BP acutely)
nitrite, hydroxocobalamin, thiosulfate (aka. sulfur)
methemoglobin
methylene blue, vitamin C
methanol, ethylene glycol (antifreeze)
fomepizole
benzodiazepines
flumazenil
TCAs
NaHCO3
tPA, streptokinase
aminocaproic acid
theophylline
beta-blocker
norepinephrine extravasation (p/w blanching of vein at site where NE is being infused)
phentolamine (alpha-1 blocker)
a pt with recent MI, 3 days later has sudden chest complaints -- cardiac auscultation reveals loud systolic murmur in the apical region. what happened?
papillary muscle rupture as part of a post-mi complication
in the evolution of an MI, what is the histologic features at each stage?
- 0-4 hrs
- 4-24 hrs
- 2-4 days
- 5-10 days
- 10+ days
0-4 hrs: no change
4-24 hrs: early coagulative necrosis, release of contents of necrotic cells into bloodstream
2-4 days: hyperemia with acute inflammation (neutrophilic emigration)
5-10 days: macrophages degraded important structural components (high risk of free wall rupture, tamponade, papillary muscle rupture, etc)

10+ days: scar tissue complete, risk of ventricular aneurysm
rapid onset sharp chest pain that radiates to the scapula
aortic dissection
rapid onset sharp pain in 20 y/o and a/w dyspnea
spontaneous pneumothorax
sharp pain lasting hrs-days and is somewhat relieved by sitting forward
pericarditis
pain made worse by deep breathing and/or motion
musculoskeletal pain
the pcwp is a good estimate of pressure in which heart chamber? what is that number?
left atrial pressure -- pcwp <12
what are the normal BPs in teh right and left ventricles?
right - <25/5
left - <130/10
what is the MOA of each class of antiarrhythmic?
"No Bad Boy Keeps Clean"

class i - na channel blocker
class ii - beta blockers
class iii - potassium (K) channel blockers
class iv - calcium channel blockers
name the drugs in each group of class 1 antiarrhythmic drugs (A,B,C)
"Police Department Question
The Little Man
For Pushing Ecstacy."

class Ia - procainimide, disopyramide, quinidine
class Ib - Lidocaine, Mexiletine
class Ic - Flecainide, Propafenone, Encainide
draw out the phases of myocardial action potential and describe which ion channels are responsible for each phase.
check answer on page 256
draw out the phases of pacemaker action potential and describe which ion channels are responsible for each phase.
check answer on page 257
which antihypertensive class or drug fits the following SEs:
1) ototoxic (esp w/ aminoglycosides)
2) dry mouth, sedation, severe rebound HTN
3) avoid in patients w/ sulfa allergy
1) loop diuretics
2) clonidine
3) diuretics (loop and thiazides are also sulfa drugs)
which antihypertensive are safe in pregnancy?
1) hydralazine
2) methyldopa
3) nifedipine
4) labetalol
which lipid-lowering agent matches the following?
1) SE: GI discomfort, bad taste
2) binds C. diff toxin
1) bile acid resins
2) cholestyramine (a bile acid resin)