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31 Cards in this Set
- Front
- Back
name the specific antidotes:
salicylates |
NaHCO3 (alkalinize urine)
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Amphetamines
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NH4Cl (acidify urine)
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antimuscarinic, anticholinergic agents
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physostigmine
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beta blockers
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glucagon
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digitalis
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stop dig, normalize K, lidocaine, anti-dig Fab fragments, Mg
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lead
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CaEDTA, succimer
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mercury
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diMERCaprol
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copper
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penicillamine
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cyanide (may be 2/2 nitroprusside use to dec severely elevated BP acutely)
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nitrite, hydroxocobalamin, thiosulfate (aka. sulfur)
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methemoglobin
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methylene blue, vitamin C
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methanol, ethylene glycol (antifreeze)
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fomepizole
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benzodiazepines
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flumazenil
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TCAs
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NaHCO3
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tPA, streptokinase
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aminocaproic acid
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theophylline
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beta-blocker
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norepinephrine extravasation (p/w blanching of vein at site where NE is being infused)
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phentolamine (alpha-1 blocker)
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a pt with recent MI, 3 days later has sudden chest complaints -- cardiac auscultation reveals loud systolic murmur in the apical region. what happened?
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papillary muscle rupture as part of a post-mi complication
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in the evolution of an MI, what is the histologic features at each stage?
- 0-4 hrs - 4-24 hrs - 2-4 days - 5-10 days - 10+ days |
0-4 hrs: no change
4-24 hrs: early coagulative necrosis, release of contents of necrotic cells into bloodstream 2-4 days: hyperemia with acute inflammation (neutrophilic emigration) 5-10 days: macrophages degraded important structural components (high risk of free wall rupture, tamponade, papillary muscle rupture, etc) 10+ days: scar tissue complete, risk of ventricular aneurysm |
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rapid onset sharp chest pain that radiates to the scapula
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aortic dissection
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rapid onset sharp pain in 20 y/o and a/w dyspnea
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spontaneous pneumothorax
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sharp pain lasting hrs-days and is somewhat relieved by sitting forward
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pericarditis
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pain made worse by deep breathing and/or motion
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musculoskeletal pain
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the pcwp is a good estimate of pressure in which heart chamber? what is that number?
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left atrial pressure -- pcwp <12
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what are the normal BPs in teh right and left ventricles?
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right - <25/5
left - <130/10 |
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what is the MOA of each class of antiarrhythmic?
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"No Bad Boy Keeps Clean"
class i - na channel blocker class ii - beta blockers class iii - potassium (K) channel blockers class iv - calcium channel blockers |
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name the drugs in each group of class 1 antiarrhythmic drugs (A,B,C)
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"Police Department Question
The Little Man For Pushing Ecstacy." class Ia - procainimide, disopyramide, quinidine class Ib - Lidocaine, Mexiletine class Ic - Flecainide, Propafenone, Encainide |
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draw out the phases of myocardial action potential and describe which ion channels are responsible for each phase.
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check answer on page 256
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draw out the phases of pacemaker action potential and describe which ion channels are responsible for each phase.
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check answer on page 257
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which antihypertensive class or drug fits the following SEs:
1) ototoxic (esp w/ aminoglycosides) 2) dry mouth, sedation, severe rebound HTN 3) avoid in patients w/ sulfa allergy |
1) loop diuretics
2) clonidine 3) diuretics (loop and thiazides are also sulfa drugs) |
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which antihypertensive are safe in pregnancy?
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1) hydralazine
2) methyldopa 3) nifedipine 4) labetalol |
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which lipid-lowering agent matches the following?
1) SE: GI discomfort, bad taste 2) binds C. diff toxin |
1) bile acid resins
2) cholestyramine (a bile acid resin) |