Displecture8-18-09

Front 1

Chemical Equivalents (pharmaceutical equivalents) are:

Back 1

two products from different companies that contain indentical active ingredients, in identical strengths, and are in the same dosage form.

Front 2

Bioequivalents are:

Back 2

Chemical Equivalents (or PE) that produce similar blood levels.

Front 3

Nonequivalents are:

Back 3

Chemical Equivalents (or PE) that do not produce similar blood levels.

Front 4

Therapeutic Alternatives:

Back 4

Drug products that contain different therapeutic moieties but which are of same pharmacological/therapeutic class that can be expected to have similar therapeutic effects when given in therapeutically equiv doses.

Front 5

Arkansas pharmacists can substitute ____ equivalents.

Back 5

therapeutic

Front 6

Pharmaceutic Alternatives:
Arkansas pharmacists ____ ____ dispense pharmaceutic alternatives.

Back 6

Drug products that contain the same therapeutic moiety and strength but differ in salt, ester or dosage form and are administered via same route.
Can not.

Front 7

Arkansas pharmacists cannot perform ____ or ____ substitution.

Back 7

pharmaceutic, therapeutic

Front 8

To know if a generic produces similar blood levels to a brand, the ____ ____ ____ ____ should be refered to. The ____ letter tells if the generic can be ____.

Back 8

FDA therapeutic equivalence codes
first
substituted

Front 9

A pharmacist may substitute ____ rated generics but may not substitute ____ rated generics.

Back 9

A, B

Front 10

Brand name products have patent protection for ____ years.

Back 10

17

Front 11

aux label for opiod analgesics:

Back 11

May cause drownsiness. Alcohol may intensifiy this effect. Use care when operating a car or dangerous machinery.

Front 12

Ceftin
generic:
class:

Back 12

generic: cefuroxime
class: cephalosporin - 2nd generation

Front 13

Demerol
generic:

Back 13

generic: meperidine

Front 14

Dilaudid
generic:

Back 14

generic: hydromorphone

Front 15

Tussionex
generic:
TC:
DF:
DI:
Polistirex is:

Back 15

generic: chlorpheniramine polistirex, hydrocodone polistirex
TC: antitussive
DF: 8mg/5ml chlorpheniramine, 10mg/5ml hydrocodone
DI: BID
Polistirex is: long acting resin - up to 12 hours

Front 16

TussiCaps Full Strength
generic:
TC:
DF:
DI:
Age:

Back 16

generic: chlorpheniramine polistirex, hydrocodone polistirex
TC: antitussive
DF: 8mg chlorpheniramine, 10mg hydrocodone
DI: BID
Age: over 12

Front 17

TussiCaps Half Strength
generic:
TC:
DF:
DI:
Age:

Back 17

generic: chlorpheniramine polistirex, hydrocodone polistirex
TC: antitussive
DF: 4mg chlorpheniramine, 5mg hydrocodone
DI: BID
Age: 6 to 12

Front 18

Methadose
generic:
ID:
DI:

Back 18

generic: methadone
ID: pain, opiod dependence including heroin
DI: Q 4 hours for pain, once daily for heroin dep

Front 19

Subutex
generic:
ID:
DF:
DI:

Back 19

generic: buprenorphine
ID: pain, opiod dependence (off label heroin)
DF: SL tab (opiod dep), IV for pain
DI: once daily for opiod dep, Q 6 hours for pain

Front 20

Suboxone
generic:
naloxone purpose:

Back 20

generic: buprenorphine, naloxone
naloxone purpose: opiod antagonist that prevents IV abuse - not effective orally

Front 21

MS Contin
generic:
DF:
DI:

Back 21

generic: morphine sulfate
DF: ER tab
DI: BID

Front 22

Kadian
generic:
DF:
DI:
Cnsl:

Back 22

generic: morphine sulfate
DF: cap filled with ER beads
DI: BID
Cnsl: DO NOT CHEW, NO ALCOHOL

Front 23

Avinza
generic:
DF:
DI:
Cnsl:

Back 23

generic: morphine sulfate
DF: cap filled with ER beads
DI: once daily
Cnsl: DO NOT CHEW, NO ALCOHOL

Front 24

Oxycontin
generic:
DF:
DI:

Back 24

generic: oxycodone
DF: ER tab
DI: Q 12 hours

Front 25

OxyIR
generic:
DI:

Back 25

generic: oxycodone
DI: Q 4 hours

Front 26

Percodan
generic:
DF:

Back 26

generic: oxycodone, aspirin
DF: IR

Front 27

Percocet
generic:
DF:

Back 27

generic: oxycodone, acetaminophen
DF: IR

Front 28

Combunox
generic:
Warning:

Back 28

generic: oxycodone, ibuprofen
Warning: aspirin allergy warning

Front 29

Opana
generic:
DI:
Cnsl:

Back 29

generic: oxymorphone
DI: Q 4 hours
Cnsl: take on empty stomach

Front 30

Opana ER
generic:
DI:
Cnsl:

Back 30

generic: oxymorphone
DI: BID
Cnsl: take on empty stomach

Front 31

Duragesic
generic:
DF:

Back 31

generic: fentanyl
DF: trandermal

Front 32

Actiq
generic:
DF:

Back 32

generic: fentanyl
DF: transmucosal - sucker rub on inside of cheek

Front 33

Onsolis
generic:
DF:

Back 33

generic: fentanyl
DF: transmucosal - buccal soluble film (like breath strips)

Front 34

Fentora
generic:
DF:

Back 34

generic: fentanyl
DF: buccal tab

Front 35

Talwin NX
generic:

Back 35

generic: pentazocine, naloxone (prevents IV abuse)

Front 36

Talacen
generic:

Back 36

generic: pentazocine, acetaminophen

Front 37

Darvon
generic:
Banned in england because:

Back 37

generic: propoxyphene HCL
Banned in england because forms cardiotoxic metabolite in high doses - few as 6 lethal when combined with alcohol

Front 38

Darvon N
generic:

Back 38

generic: propoxyphene napsylate

Front 39

Darvocet N
generic:
DF:

Back 39

generic: propoxyphene napsylate and acetaminophen
DF: N50 (50mg propoxyphene, 325mg APAP), N100 (100mg propoxyphene, 650 APAP)

Front 40

Darvocet A 500
generic:
DF:

Back 40

generic: propoxyphene napsylate and acetaminophen
DF: 100mg propoxyphene, 500 APAP

Front 41

Ultram IR
generic:
DI:

Back 41

generic: tramadol
DI: Q 4 hours

Front 42

Ultram ER
generic:
DI:

Back 42

generic: tramadol
DI: once a day

Front 43

Ultracet
generic:

Back 43

generic: tramadol, APAP

Front 44

Max 24 hour dose of tramadol

Back 44

400mg for IR, 300mg for ER formulations

Front 45

tramadol warning:

Back 45

use carefully in patients with seizure disorder - can cause seizure in healthy adults. Titrate from low dose to prevent seizures.

Front 46

Nucynta
generic:
Marketed as:
Controlled class:

Back 46

generic: tapentadol
Marketed as: similar to tramadol with lower seizure risk
Controlled class: C2

Front 47

Opiods constipation rank
least: (4)
more: (2)
most: (1)

Back 47

least: codeine, meperidine, hydromorphone, methadone
more: morphine, oxycodone
most: oxymorphone

Front 48

Relistor
generic:
TC:
ID:
Mech of action:
DF:

Back 48

generic: methylnaltrexone
TC: opiod antagonist
ID: constipation due to opiods
Mech of action: blocks opiod receptors in GI, methyl group prevents it from entering CNS
DF: SC injection Q other day

Front 49

seizure affecting both hemispheres, impaired consciousness

Back 49

Generalized

Front 50

seizure affect one hemisphere, may or may not impair consciousness:
AKA:

Back 50

partial
AKA: focal seizure

Front 51

full blown generalized seizure

Back 51

tonic-clonic

Front 52

absence seizure

Back 52

petit mal

Front 53

Warning for patients taking anti-convulsants

Back 53

Must not discontinue suddenly esp for patients with generalized seizures. May cause continuous tonic-clonic seizure W/O regaining consciousness - life threatening

Front 54

continuous tonic-clonic seizure W/O regaining consciousness - AKA

Back 54

Status Epilepticus

Front 55

phenobarbital
TC:
class:
ID:
Cnsl:

Back 55

phenobarbital
TC: anticonvulsant
class: barbiturates
ID: partial and tonic clonic seizures
Cnsl: decrease the effect of contraceptives

Front 56

Mebaral
generic:
TC:
class:
ID:
Cnsl:

Back 56

generic: mephobarbital
TC: anticonvulsant
class: barbiturates
ID: partial and tonic clonic seizures
Cnsl: decrease the effect of contraceptives

Front 57

Dilantin
generic:
TC:
class:
ID:
Cnsl:

Back 57

generic: phenytoin
TC: anticonvulsant
class: hydantoins
ID: partial and tonic-clonic seizures
Cnsl: decrease the effect of contraceptives

Front 58

Peganone
generic:
TC:
class:
ID:
Cnsl:

Back 58

generic: ethotoin
TC: anticonvulsant
class: hydantoins
ID: partial and tonic-clonic seizures
Cnsl: decrease the effect of contraceptives

Front 59

Cerebyx
generic:
TC:
class:
ID:

Back 59

generic: fosphenytoin
TC: anticonvulsant
class: hydantoins
ID: IV dosage form used in hospitals for Status Epilepticus

Front 60

Zarontin
generic:
TC:
class:
ID:

Back 60

generic: ethosuximide
TC: anticonvulsant
class: succinimides
ID: absence seizures

Front 61

Celontin
generic:
TC:
class:
ID:

Back 61

generic: methsuximide
TC: anticonvulsant
class: succinimides
ID: absence seizures

Front 62

Zonegran
generic:
TC:
class:
ID:
Cnsl:

Back 62

generic: zonisamide
TC: anticonvulsant
class: sulfonamides
ID: partial seizures
Cnsl: may cause oligohydrosis - decreased sweating. Contraindicated in patients allergic to sulfas

Front 63

Tegretol
generic:
TC:
ID:
BB:
Cnsl:

Back 63

generic: carbamazepine
TC: anticonvulsant
ID: partial and tonic-clonic seizures, pain associated with trigeminal neuralgia, manic episodes of bi-polar disorder.
BB: agranulocytosis
Cnsl: decreases effectiveness of contraceptives

Front 64

Carbatrol
generic:
TC:
ID:
BB:
Cnsl:

Back 64

generic: carbamazepine
TC: anticonvulsant
ID: partial and tonic-clonic seizures, pain associated with trigeminal neuralgia, manic episodes of bi-polar disorder.
BB: agranulocytosis
Cnsl: decreases effectiveness of contraceptives

Front 65

Epitol
generic:
TC:
ID:
BB:
Cnsl:

Back 65

generic: carbamazepine
TC: anticonvulsant
ID: partial and tonic-clonic seizures, pain associated with trigeminal neuralgia, manic episodes of bi-polar disorder.
BB: agranulocytosis
Cnsl: decreases effectiveness of contraceptives

Front 66

disorder of the 5th cranial nerve - causes pain in middle of face

Back 66

trigeminal neuralgia

Front 67

Trileptal
generic:
TC:
ID:
Cnsl:

Back 67

generic: oxcarbazepine
TC: anticonvulsant
ID: partial seizures
Cnsl: 30% of patients allergic to carbamazepine will be allergic to oxcarbamazepine. Decreases effectiveness of contraceptives.

Front 68

Felbatol
generic:
TC:
ID:
BB:

Back 68

generic: felbamate
TC: anticonvulsants
ID: partial and certain types of generalized seizures
BB: agranulocytosis and hepatotoxicity. Drug of last resort.

Front 69

Neurontin
generic:
TC:
ID:

Back 69

generic: gabapentin
TC: anticonvulsant
ID: partial seizures, pain assoc with postherpetic neuralgia.

Front 70

Lyrica
generic:
TC:
ID:

Back 70

generic: pregabalin
TC: anticonvulsant
ID: partial seizures, postherpetic neuralgia, diabetic peripheral neuropathy, fibromyalgia

Front 71

Lamictal
generic:
TC:
ID:
BB:

Back 71

generic: lamotrigine
TC: anticonvulsant
ID: partial and tonic-clonic seizures, BOTH manic and depressive phases of bi-polar disorder
BB: may cause serious rashes which can become permanently disfiguring

Front 72

Keppra
generic:
TC:
ID:
SALAD:

Back 72

generic: levetiracetam
TC: anticonvulsant
ID: partial and tonic-clonic seizires
SALAD: Kaletra (AIDS drug) - lopinavir, ritonavir (protease inhibitors)

Front 73

Mysoline
generic:
TC:
ID:
Cnsl:

Back 73

generic: primidone
TC: anticonvulsant
ID: partial and tonic-clonic seizures
Cnsl: CI in patients allergic to phenobarbital bc primidone is met to phenobarbital. Decreases effect of contraceptives

Front 74

Gabitril
generic:
TC:
ID:

Back 74

generic: tiagabine
TC: anticonvulsant
ID: partial seizures

Front 75

Topamax
generic:
TC:
ID:
Cnsl:

Back 75

generic: topiramate
TC: anticonvulsant
ID: partial and tonic-clonic seizures, migraine prophylaxis
Cnsl: oligohydrosis, decrease effect of contraceptives

Front 76

Depakote
generic:
TC:
ID:
BB:

Back 76

generic: divalproex sodium
TC: anticonvulsant
ID: partial and absence seizures, migraine prophylaxis, manic episodes of bi-polar disorder
BB: hepatotoxicity, pancreatitis, teratogenic effects

Front 77

Banzel
generic:
TC:
ID:

Back 77

generic: rufinamide
TC: anticonvulsant
ID: Lennox-Gastaut Syndrome - severe form of epilepsy. Both tonic-clonic and absence seizures, onset in very young children, usually those with some deg of mental retardation

Front 78

Vimpat
generic:
TC:
ID:

Back 78

generic: lacosamide
TC: anticonvulsant
ID: partial seizures

Front 79

amitriptyline
TC:
class:
ID:

Back 79

generic: amitriptyline
TC: antidepressants
class: tricyclics
ID: depression

Front 80

Anafranil
generic:
TC:
class:
ID:

Back 80

generic: clomipramine
TC: antidepressant
class: tricyclics
ID: OCD
Side effect: inadvertant orgasm when yawning in 5% patients

Front 81

doxepin
TC:
ID:

Back 81

generic: doxepin
TC: antidepressant
class: tricyclics
ID: depression

Front 82

Norpramin
generic:
TC:
ID:

Back 82

generic: desipramine
TC: antidepressant
class: tricyclics
ID: depression

Front 83

Tofranil
generic:
TC:
ID:

Back 83

generic: imipramine
TC: antidepressant
class: tricyclics
ID: depression

Front 84

Pamelor
generic:
TC:
ID:

Back 84

generic: nortriptyline
TC: antidepressant
class: tricyclics
ID: depression

Front 85

Paxil
generic:
TC:
class:

Back 85

generic: paroxetine
TC: antidepressant
class: selective serotonin reuptake inhibitors
ID: depression, PMDD

Front 86

Zoloft
generic:
TC:
class:

Back 86

generic: sertraline
TC: antidepressant
class: selective serotonin reuptake inhibitors
ID: depression, PMDD

Front 87

Luvox CR
generic:
TC:
class:
ID:

Back 87

generic: fluvoxamine
TC: antidepressant
class: selective serotonin reuptake inhibitors
ID: only ID for OCD

Front 88

Celexa
generic:
TC:
class:
ID:

Back 88

generic: citalopram
TC: antidepressant
class: selective serotonin reuptake inhibitors
ID: depression

Front 89

Lexapro
generic:
TC:
class:
ID:
Isomer:

Back 89

generic: ezcitalopram
TC: antidepressant
class: selective serotonin reuptake inhibitors
ID: depression
Isomer: isolated S-isomer of citalopram

Front 90

Prozac
generic:
TC:
class:
ID:

Back 90

generic: fluoxetine
TC: antidepressant
class: selective serotonin reuptake inhibitors
ID: depression

Front 91

Sarafem
generic:
TC:
class:
ID:

Back 91

generic: fluoxetine
TC: antidepressant
class: selective serotonin reuptake inhibitors
ID: only ID for PMDD - Premenstrual dysphoric disorder, depression occuring week before menses.

Front 92

Yaz
generic:
ID:

Back 92

generic: drospirenone, ethinyl estradiol
ID: contraception, PMDD

Front 93

Effexor
generic:
TC:
class:
ID:

Back 93

generic: venlafaxine
TC: antidepressants
class: selective serotonin and norepinephrine reuptake inhibitors
ID: depression

Front 94

Pristiq
generic:
TC:
class:
ID:
active metabolite of:

Back 94

generic: desvenlafaxine
TC: antidepressants
class: selective serotonin and norepinephrine reuptake inhibitors
ID: depression
active metabolite of: venlafaxine

Front 95

Cymbalta
generic:
TC:
class:
ID:

Back 95

generic: duloxetine
TC: antidepressants
class: selective serotonin and norepinephrine reuptake inhibitors
ID: depression, pain assoc with diabetic peripheral neuropathy, fibromyalgia

Front 96

Savella
generic:
TC:
class:
ID:

Back 96

generic: milnacipran
TC: antidepressants
class: selective serotonin and norepinephrine reuptake inhibitors
ID: for fibromyalgia only

Front 97

maprotiline
TC:
class:
ID:

Back 97

generic: maprotiline
TC: antidepressant
class: tetracyclics
ID: depression

Front 98

Remeron (SolTab)
generic:
TC:
class:
ID:

Back 98

generic: mirtazapine
TC: antidepressants
class: tetracyclics
ID: depression

Front 99

Wellbutrin (SR) (XL)
generic:
TC:
class:
ID:
DI:

Back 99

generic: bupropion
TC: antidepressant
class: aminoketones
ID: depression, smoking cessation, seasonal affective disorder - ONLY drug approved for this.
DI: TID, SR - BID, XR - once daily

Front 100

nefazodone
TC:
class:
ID:
BB:

Back 100

generic: nefazodone
TC: antidepressants
class: phenylpiperazines
ID: depression
BB: hepatotoxicity

Front 101

Desyrel
generic:
TC:
class:
ID:

Back 101

generic: trazodone
TC: antidepressants
class: triazolopyridines
ID: depression, mainly used for insomnia today