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30 Cards in this Set

  • Front
  • Back
ACE Inhibitors
1. Persistent cough may develop (nonproductive, starts 1 week or so after initial dose, about 5% incidence, more common in women, cough goes away about 1 week after discontinuing)
2. Do not use in pregnancy (this is a BBW, drugs that affect renin-angiotensin system can cause birth defects in the 1st trimester, can cause renal failure in 2nd and 3rd trimesters)
3. Avoid salt substitutes (they are potassium based, ACE inhibitors tend to raise potassium levels, could lead to hyperkalemia)
4. Captopril and moexipril need to be taken on an empty stomach (food decreases absorption, this also applies to Capozide and Uniretic)
Angiotensin II Receptor Antagonists
1. Do not use in pregnancy (this is a BBW, they affect the renin-angiotensin system).
2. Avoid salt substitutes (they are potassium based and tend to raise potassium levels, which could lead to hyperkalemia)
Renin Inhibitors
1. Do not use in pregnancy (this is a BBW, these affect the renin-angiotensin system)
2. Take on an empty stomach
3. Persistent cough may develop
Inhaled Corticosteroid
1. Rinse mouth with water after use (to avoid thrush, do it 15-20 minutes after work)
Antiarrhythmic
1. May cause unusual heartbeat (all can cuase new or worsening arrhythmias called proarrhythmic effects)
Amiodarone
1. May cause breathing problems and visual disturbances
Coumadin
1. Avoid changing diet (large intake of Vitamin K would need higher Coumadin dose)
Bile Acid Sequestrants
1. May cause constipation
2. Take with plenty of water (Questran, Prevalite, and Colestid are all powders and Welchol is a large tablet)
3. May interfere with absorption of other drugs (bind to other medications, patients need to take other drugs 1 hour before or 4 hours after)
HMG-CoA Reductase Inhibitors
1. May cause muscle pain, weakness, or dark urine
Lovastatin
1. Take with food
Alpha-1 Adrenergic Blockers
1. May cause syncope with 1st few doses (fainting, this could also happen with a dose increase, they cause a drop in blood pressure, patients need to be laying down)
Cytoxan
1. Drink plenty of water (it cause hemorrhagic cystitis)
Methotrexate
1. May cause fever or sore throat
Benzodiazepine
1. May cause drowsiness (somnolence)
2. Avoid alcohol
3. Do not discontinue therapy abruptly
Beta Blockers
1. Do not discontinue suddenly (could cause a dangerous increase in blood pressure)
2. Take sotalol on an empty stomach.
Digoxin
1. May cause nausea, vomiting, and vision problems (signs of digoxin toxicity, patients see colored halos around things)
Loop and Thiazide Diuretic
1. May cause muscle cramps, unusual tiredness, or weakness (symptoms of hypokalemia, normal serum potassium levels are 3.5-5 mEq)
2. May cause photosensitivity
3. Take early in the morning (avoid nocturia – excessive urination at night)
Potassium Sparing Diuretic
1. Hyperkalemia may occur (have blood checked)(this is a BBW)
2. Avoid salt substitutes
3. Take early in the morning
Hydantoin (oral)
1. Use good dental care (can cause gingival hyperplasia, gums swell and grow, could cover teeth; brush and floss; the highest incidence is in children)
2. Avoid alcohol (lowers blood level of phenytoin)
3. Do not discontinue therapy abruptly (can trigger status epilepticus)
4. Decrease the effectiveness of oral contraceptives
MAO Inhibitors
1. Avoid cheese, certain types of fish, sausage, alcohol, caffeine, chocolate, and some fruits (bananas and raisins). (These contain tyramine, which can lead to a hypertensive crisis because tyramine is structurally related to Epi and NE).
2. Avoid OTC nasal decongestants (they are sympathomimetics and add to the increase of Epi and NE; this can lead to a hypertensive crisis)
MUSE
1. Urinate prior to inserting (residual urine will help dissolve)
Viagra/Levitra
1. Take 1 hour prior to sexual activity (1 tablet every 24 hours max)
2. Take on an empty stomach (food decreases absorption by 50%)
Cialis
1. Take without regard to meals
NSAID
1. Take with food
Ophthalmic NSAID
1. Will cause burning on administration
Antabuse
1. Do not drink alcoholic beverages
Metronidazole
1. Do not drink alcoholic beverages (10% chance of disulfiram reaction)
Isotretinoin
1. Contraindicated in pregnancy
2. Take with food (increases blood levels)
3. Causes phototoxicity
Nitroglycerin
1. Avoid alcohol (causes hypotension and headache)
Antiretroviral
1. Take exactly as directed, do not skip doses (this increases the chance of drug resistance)