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14 Cards in this Set

  • Front
  • Back

What are excipients

They are substances with slight or no therapeutic value but are used in the preparation of various pharmaceuticals

What is a preservative

A preservative is a substance added to foods or pharmaceuticals, paints, biological samples and woods to prevent decomposition

State some physical and chemical preservatives

Chemical


Benzoic acid


Sorbic acid


Hydroxybenzoates


Benzyl alcohol


Chloroform water



Physical


Refrigeration


Drying

State 5 ideal properties of preservatives

1. It should be non toxic


2. It should not be irritant


3. It should be chemically and physically stable


4. It should be compatible with other ingredients used in the formulation


5. It must be potent

State 4 artificial preservatives

Sodium benzoate


Sodium bisulphite


Potassium sorbate


Sorbic acid

State 3 natural preservatives

1. Quaternary ammonium salts


2. Alcohols


3. Phenols

What are flavoring agents?

They are substances that give flavor to pharmaceutical preparations or they mask the bitter taste of drugs

State 4 natural flavoring agents

1. Peppermint oil


2. Anise oil


3. Lemongrass oil


4. Ginger oil


5. Aldehyde (vanillin)

What are artificial flavoring agents

These are chemical compounds synthesized by chemical processes that may be organoleptic ally and chemical structurally indistinguishable to a natural flavoring agent

State 3 examples of artificial flavoring agents

1. Ethyl butyrate


2. Amyl acetate


3. Methyl salicylate

State 4 ideal properties of flavoring agents

1. Should be inert


2. Should increase the palatability of the pharmaceutical preparation


3. Should be non toxic


4. Should provide pleasant odour and taste of drugs product

Def 1: What are diluents? Eg.1


They are substances added to increase the volume of a pharmaceutical preparation. Eg. Alcohol and water

Def 2: What are diluents? Eg. 2

They are fillers designed to make up the required bulk of the drug when the drug dosage amount is inadequate. Eg. Starch, lactose, sorbitol, mannitol calcium carbonate.

State 5 ideal properties of diluents

1. It should be nonhygroscopic


2. It should be chemically inert


3. It should be stable


4. It should be water soluble


5. It should be cost effective