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33 Cards in this Set

  • Front
  • Back
The brain alters rate and depth of respiration mostly due to alteration in the amount of what substance in the blood?
Carbon dioxide
Increased respiration caused by?
Increased CO2

Decreased O2

Decreased pH
What does Decreased CO2 and Increased pH cause?
Decreased respirations
Inadequate oxygen in blood
Hypoxemia

Low arterial O2
Low hemoglobin saturation
Hypoxia
Inadequate oxygen in tissues
Difficult to measure
Assumed abnormal if PaO2 is abnormal
Rate/Rhythm Abnormalities
Decreased LOC
Muscle weakness
Temperature
Anxiety
CO2 narcosis
Drugs
narcotics
recreational
V =
Amount of air in and out of lungs
Amount of blood flow inside lungs
Q
Normal V-Q match/Ratio
4/5 or 0.8
Lung Perfusion
Gravity dependent

Perfusion greatest in dependent lung area
Causes of poor Ventilation
Airway obstruction
Mucus
Edema
Restrictive diseases
Atelectasis
Compensatory hypoxemic vasoconstriction
Alveolar dead space
Alveoli well-ventilated but not adequately perfused

ventilation is wasted
Causes of poor perfusion
Pulmonary emboli
Sudden dyspnea
fat emboli
DVT
Severe hypoxemia
Obstructive Pulmonary Disease (OPD)
Inspiration
Airways open wider

Expiration
Airways narrow
OPD Characteristics
Trapped air

Increased lung compliance
"elasticity of lung"
Intermittent airway obstruction

Spasm of smooth muscle

Edema of bronchial mucosa

Secretion of excessive thick mucus
Asthma
Asthma Etiology
Intrinsic
Allergens - foods, animals, meds

Extrinsic
URI
Smoking
Emotional stress, exercise
Asthma Prevention
Inhaled corticosteriods often 1st choice
Status Asthmaticus
Severe respiratory distress

Unresponsive to initial therapy
Epinephrine drug of choice
COPD Risk Factors
Particles
Genes
Age - avg age 70; avg in KY 50
Gender
Oxidative stress
Altered lung growth and development
Prematurity
CF
Poor nutrition
Comorbidities
Respiratory infections
Socioeconomic status
Emphysema
Destruction of alveoli

Decreased surface area for gas exchange

Airway collapse

Air trapping
Etiology of Emphysema
Smoking

Mucosal inflammation

Elastase enzyme decreased

Alveoli destroyed
Coughing > 3 months x 2 years
Chronic Bronchitis

Etiology
Smoking
Air pollution
Clinical Manifestations of Chronic Bronchitis
Productive cough
Fever
Anorexia
Weight loss
Fatigue
Empyema
Pus
Low Protein Fluid
Transudate
High Protein Fluid
Exudate
Hemothorax
Blood
Chylothorax
Lymph
Pleural Effusion Tertiary Prevention
Thoracentesis - sticking needle into thorax
Drainage
Pneumothorax
Simple
Air in pleural cavity

Tension
Trauma
Pneumoconioses
Seen in coal mine workers and glass blowers

Black lung
Silicosis
Asbestosis
Foreign particles
Inflammatory process

Decreased lung elasticity
Primary Prevention of Pneumoconioses
Environmental control of air-borne non-biodegradable substances

Protective gear