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17 Cards in this Set

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Main points for managing uncomplicated DM in the cat?

1) Remission


2) Twice- three times daily caninsulin and if this doesn't lead to remission within 4 weeks switch to glarginine.


3) Cats retain normal feeding schedule.


4) Weight reduction.


5) Start on a dose of 0.25 UI/kg


) Revisit 1 week later.

What should we warn owners with as a serious complication of insulin therapy?

Signs of hypoglycaemia.

What is glipizide?

A drug that stimulates insulin secretion from beta cells.

Once diabetes has been brought under control how often should animal be brought for check ups?

every 2 months

Name a serious complication of DM and signs of it? What is diangosis based on?

Ketoacidosis.


Inappetance, vomiting, lethargy and collapse.


Presence of ketones in the blood and urine.


Hyperglycaemia, ketoanemia, metabolic acidosis and imbalances in electrolytes such as potassium, phosphate and sodium.



A patient comes into your practice with diabetic ketoacidosis what must we do first?

Place a central intravenous line and run an electrolyte panel.

How do we address the hypovolaemia with diabetic ketoacidosis?

1) Assess degree of dehydration, calculate fluid deficit, add in maintenance.


2) Administer shock doses of isotonic crystalloid like 0.9% hartmanns saline. 90 ml/kg in first few hours and then rest over 12-24 hours.


3) For cats give 5-10 ml/kg as less well tolerated.

Other than hydration status, and addressing the hypovolaemia what else must we monitor in a cat with diabetic ketoacidosis?

Urinary output >2ml/kg/hr

Once hypovolaemia has been addressed what must we do in a patient with diabetic ketoacidosis if a fluid pump is available?

Start insulin therapy.


Make up soluble insulin in 0.9 % NaCl and give until blood glucose falls below 15 mmol/l.


If it falls below 10 give 2.5- 5% dextrose saline

If a fluid pump is not available how can we administer insulin therapy in a ketoacidotic patient?

Inject soluble insulin intramuscularly hourly.



What electrolyte is moved into the cell during ketoacidosis? Why is it important we address this?

Potassium.


It will delay eating.

How do we correct hypophosphataemia in DKA?

If it drops below 0.35 mmol/l supplement as can lead to severe haemolytic anaemia.

How should we address patients with hypo-hyper natraemia with DKA and what should be cautious of?

Don't adjust to rapidly as can cause cerebral oedema or dehydration.

How can we address the acidosis of DKA?

Sodium bicarbonate I/V only if ph below 7.1

In summary how do we address a patient with DKA?

1) FLUIDS - Correction of hypovolaemia


2) Monitor urine output.


3) Start insulin therapy


4) Address the hypokalaemia


5) Address phosphate issues


6) Address sodium imbalances


7) Treat the acidosis.

What are common reasons for a failure to stabilise DM?

Poor owner injection technique.


Poor storage.


Out of date insulin.


Shaking insulin.


Incorrect feeding.



What are signs of hypoglycemia in a DM patient we are trying to stabilize? How should we treat these patients?

Anxiety, muscle tremors, ataxia, collapse, convulsions, coma and death.




Treat with a high glucose meal.




If unconscious give IV glucose.