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19 Cards in this Set
- Front
- Back
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Disorders of Sex Developments (DSD)- Part I ***************Flip card for instructions! ******************** |
Identify the 1) sex chromosomes, 2) gonads, 3) internal sex organ & 4) external genitalia for each of the DSDs.
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Turner's Syndrome |
Sex Chromosomes: X0 Gonads : Ovaries Internal Sex Organ: Mullerian System External Genitalia : Clitoris & Labia |
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Congenital Adrenal Hyperplaxia (CAH) |
Sex Chromosomes: XX Gonads : Ovaries Internal Sex Organ: Mullerian System* External Genitalia : Penis, Scrotum
*Development of the Adrenal glands occurs AFTER accessory organs differentiation. Thus, no effect of Androgens (T) was seen on the internal sex organ. |
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Complete Androgen Insensitivity Syndrome (CAIS) |
Sex Chromosomes: XY Gonads : Testes Internal Sex Organ: -* External Genitalia : Clitoris & Labia
*PRESCENCE of MIH degenerates the Mullerian system. ABSCENCE of Androgen receptors FAIL to develop the Wolffian system & FAIL to masculinize the external genitalia. |
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Klinefelter Syndrome |
Sex Chromosomes: XXY/ XYY Gonads : Testes Internal Sex Organ: Wolffian System External Genitalia : Penis & Scrotum*
*XXY individuals have underdeveloped male external genitalia and gynecomastia (breast development in males). |
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5 Alpha- Reductase Deficiency |
Sex Chromosomes: XY Gonads : Testes Internal Sex Organ: Wolffian System External Genitalia : Clitoris & Labia*
*ABSCENCE of enzyme 5 Alpha-Reductase to convert Testosterone into DHT, which is responsible for the masculinization of the male external genitalia. |
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Sexual Differentiation & Behaviors- Part II ***************Flip card for instructions! ******************** |
Determine the sexually dimorphic behaviors in each of the hypothetical scenarios. |
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Male rats are castrated at day 1 and injected with estrogens & progestins in adulthood. |
Female sexual behaviors (lordosis). |
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Female rats are ovariectomized at day 1 and injected with Testosterone in adulthood. |
No male sexual behaviors (mounting). |
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Male rats are castrated at day 1 and injected with Testosterone in adulthood. |
Female sexual behaviors (lordosis). |
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Male rats are castrated at day 1 and injected with Testosterone immediately. Testosterone was given again in adulthood. |
Male sexual behaviors (mounting). |
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Male rats are castrated at day 20 and injected with Testosterone in adulthood. |
Male sexual behaviors (mounting). |
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Male rats are castrated at day 20 and injected with Estrogens & Progestins immediately. Estrogens & Progestins are again injected later in adulthood. |
No female sexual behaviors (lordosis). |
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Female rats are ovariectomized at day 1 and injected with Testosterone before day 10. Testosterone is given again in adulthood. |
Male sexual behaviors (mounting). |
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Male rats are castrated at day 1 and injected with Testosterone on day 20. Testosterone is given again in adulthood. |
No male sexual behaviors (mounting). |
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Male rats are castrated at day 1 and injected with Testosterone on day 20. Estrogens & progestins are given again in adulthood. |
Female sexual behaviors (lordosis). |
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Male rats are castrated in adulthood and injected with estrogens & progestins. |
No female sexual behaviors (lordosis). |
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Female rats are ovariectomized in adulthood and injected with Testosterone. |
No male sexual behaviors (mounting). |
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THE END ******** All the best for the exam! :) ******** |
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