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19 Cards in this Set

  • Front
  • Back

Tonsilitis



1. Inflammatory Cells in the Epithelium


2. Lymphoid Hyperplasia


Tonsilitis



- arrow notes inflammatory cells (lymphocytes here)


- note that the tonsil is a non encapsulated lymph organ

Chronic Lymphadenitis



1. Sinuses


2. Germinal Centers and Histocytes


Caseating Granuloma: Classically in TB and fungal infections. Omaha Histoplasmosis is most likely cause.

Caseating Granuloma


1. Lymphocytes


2. Macrophages and Epithelioid Cells


3. Caseous Material (amorphous and eosinophilic)

Tuberculous Granuloma



- Note the Langhans Giants cell in the lower left


- Langhans cells are large multinucleated cells formed by the fusion of macrophages and contain nuclei in a horseshoe shape.



Epithelioid Cells:


Located around the center of a granuloma. Named bc they have lots of pink cytoplasm similar to squamous epithelial cells. Nuclei tend to be elongated

Non-Necrotizing Granuloma:


- Generally indicative of a non-infectious etiology (Chrohn's Disease, hypersensativity, drug reactions)


- May occur with Necrotizing Granulomas (which do indicate an infectious agent)


Non-Necrotizing Granuloma: Note there is no casseation and the elongated nuclei within the histocytes.

Metastatic Carcinoma in Subcapsular Sinus

Metastatic Carcinoma in Subcapsular Sinus

Thymoma: note classic jigsaw pattern

Thymoma:

Thymoma: proliferation of the epithelial cells (these are NOT lymphoid tumors)

Thymoma: proliferation of the epithelial cells (these are NOT lymphoid tumors)

Splenic Infarcts with coagulation necrosis. Note the triangle shape of the infarcts

Splenomegaly:


Normal Spleen is 150g while this spleen was 1500g. Again note the triangle shaped infarcts.

Perisplenitis: Here we have a "sugar icing" of thickened fibrous tissue on the capsule. This is not very clinically significant.

Lacerated Spleen:


Trauma is a common cause for splenectomy. Spleen is much more susceptible if the it is already enlarged.