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28 Cards in this Set

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  • Back
What type of epithelium lines the esophagus compared to the rest of the GI tract?
squamous cell epithelium vs columnar in the rest of the GI tract
Manometry helps differentiate between?
Hiatal hernia vs GERD
***Type 1 Hiatal Hernia
-"sliding"
-goes through the diaphragm
-MC hernia
-100:1 (compared to paraesophageal)
Type 2 Hiatal Hernia
-Paraesophageal
-part of the stomach pushes on the side
What is the Patho of Type 1 Hiatal Hernia?
-LES sphincter mechanism becomes incompetent - not a "true" sphincter
-reflux of acid gastric juice
-may lead to mucosal erosion, ulceration, and scarring
Prevalence of Type 1 Hiatal Hernia***
-MC in women who have been prego
-M&F w/ inc intrabd pressure
-***w/ reflux is freq found in pts who are overweight, due to incr intraabd pressure pushing upwards
-many pts have no sx
Symptoms of Type 1 Hiatal Hernia***
-burning epigastric or substernal pain or tightness, w/ no radiation
-confused w/ pain of MI
-**Put pt lying and upsidedown -> stomach will go above diaphragm if there is a hernia -> able to see w/ xray or endoscopy
What late symptoms of Type 1 Hiatal hernia suggest stricture formation?
-dysphagia and vomiting
What is the clinical presentation of Type 2 Hiatal Hernia***
-generally no sx until they incarcerate and become ischemic
-**dysphagia, bleeding, occasionally resp distress are the presenting sx
-very dangerous and rare but needs surgery every time!***
What confirms hiatal hernia and reflux esophagitis diagnosis?***
Fluoroscopy using a barium swallow
Tx of hiatal hernias
1. avoidance of gastric stimulants
2. Elimination of tight garments
3. Reg use of antacids
4. inc the pH of reflux gastric juice (H blockers, maybe metoclopramide
5. don't eat/drink before bed
6. wt loss in obese pts
What is surgical nissen fundoplication?**
-wrap gastric fundus stomach around the LES and stitch in place
-when stomach contracts it closes the esophagus instead of putting gastric acid into it (no GERD)
Highlights of Achalasia***

(see Jones for more info)
-failure to relax not due to spasm
-painless dyspagia
-asp PNA is common
-complain of spitting up foul-smelling secretions simply when leaning forward
***Diagnosis and Tx of Achalasia
-*dilation of proximal esophagus is classic, "bird's beak" on Xray
-med tx not helpful
-***surgical transaction of the muscle, esophageal myotomy--> Tx of choice
What is the 2nd MC manifestation of esophageal motility disorders?***
-Esophageal Diverticulum
-Pulsion or traction --> depending on the mech that leads to their development (pulsion MC)
*What are Cervical (Zenker's) dirverticula?
-pulsion are are closely related to dysfxn of cricopharyngeal muscle
-c/o regurg of recently swallowed food
-putrid breath odor
-tx by excision of diverticula and myotomy of circopharyngeal muscle
Diverticula of the distal third of the esophagus are a/w?
-dysfunction of the esophagogastric junction as a result of chronic stricture from acid reflux, antireflux surgical procedures, achalasia
Diverticula of the middle third of the esophagus are a/w?
-mediastinal inflammation from TB or histoplasmosis, which results in scar formation and subsequent contracture that places "traction" on the esophagus
Benign Esophageal Neoplasms
-rare, leiomyomas are the MC intramural tumors
-potential for malig degen quite low
-indent the lumen of esophagus on contrast radiography
Malignant Esophageal Neoplasms
-usually arises from squamous epi
-commonly in black men in a/w alcohol or tobacco abuse
***~10% of pts w/ Barrett's esophagus will have adenoCA
Making the diagnosis of Malignant Esophageal Neoplasms***
-***Endoscopy is the gold standard of diagnosis w/ biopsy
-operate on the type and stage of the cancer. Need to see extent of tumor involvement via CT of chest and upper abd
-"Apple core" on barium swallow
How do you tx tumors in the upper esophagus?
-radiotx is the primary mode
-surgery tx, take part of jejunum
How do you tx tumors in the middle esophagus?
-usually tx by a staged procedure w/ total thoracic esophagectomy and bypass
How do you tx tumors in the lower esophagus?
-best tx by esophagogastric resection and end to end anastomosis in mid chest
What is a Bochdalek type of diaphragmatic hernia?
-stomach in chest due to rupture of diaphragmatic hernia
-place nasogastric tube to decompress stomach
What happens in traumatic rupture of the diaphragm?
-it is from inc intra-abd pressure
-displacement of lung
-stomach is above diaphragm
-can also see spleen above b/c it is attached to the stomach
***What is Boerhavve's syndrome
-spontaneous perforation secondary to forceful vomiting
What happens when you ingest caustic material?
-inspect mouth to assess injury
-neutralization and induced emesis is not usually recommended, bc caustic material will redamage esophagus
-endscopy, airway, patency of esophagus, NO STEROIDS