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34 Cards in this Set

  • Front
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What are the layers of the skin and what the they contain?

1. The epidermis is the top layer that contains epithelial cells and keratin


2. The dermis is second layer that contains hair follicles and oil/sweat glands.


3. The subcutaneous contends adipose tissue

What are the antibiotic roles of sebum and perspiration?

They're high in salt which inhibits some microbes.


Contains lysosomes that hydrolyze peptidoglycan


The fatty acids inhibit some bacteria.

Whata r ethe normal microbiota of the skin

Gram +:


Staphylococcus Aureus


Micrococci


dipthernoids


propionibacterium acnes


yeast


Exanthem vs Enanthem

Exanthem is a skin rash


Enanthem is a mucous membrane rash.

Vesicle?


Bulla?


Pustule?


Macule

round pus filled lesion in epidermis


flat/rounf pus filled lesion in epidermis


Pus in the the dermis surrounded by tissue


flat lesion on surface of skin


Inflammatory Acne

caused by propionibacterium acnes


it is gram + and anerobic



treated with antibiotic and benzoyl peroxide

Virulence factors of Staphylococcus aureus

High salt


Leukocidal


Protein A


resistent to lysozmes

What's protein A?

protein A neutralize antibodies

Staphylococcus skin infections

SSSS


TSS


Sty


Folliculitis


furnuncle/ boil


Abcesses

Streptococcus virulence?

contains Protein M


superantigen


Exotoxin A


Staphylococcus skin infections

TSS


Flesh eating diseases


necrotizing fascilitis



What is Protein M?

Protein M cause neutrophils to bind and release damaging cytokines.

Virulence and infections of Pseudomas

Gram NEG


pyocyanin toxin


opportunistic


causes blue-green pus



Causes Swimmer ear or Otitis externa

What are the viral skin infections?

Warts


Smallpox


Chickenpox


Shingles


Measels


Rubella


Herpes (cold sores)


5th disease: erthema infectiosum


Roseola

Warts

Caused by papillomavirus


benign skin growth sometimes associated with cancer



treatment by freezing, acid, or laser removal

Smallpox

caused by the poxvirus Variola


Erradicated by vaccines


Chicken Pox

Caused my Varciela zoster virus (HHV 3)


remans latent in dorsal root ganglion


transmitted via resp tract

SHingles

caused by the reactivation of latent VCR


live attenuated vaccine and acyclovir

Measels

caused by rubeola?


Macular rash spots ect

Rubella

Congenital Rubella syndrome damaging to infants.


macular rashes

erthema infectious 5th diseae

caused by parvovirus b19


starts as a facial rash

roseola

caused by HHV- 6 or 7.


high fever and rash lasting 1-2 days

Fungal infections of the skin

Cutaneous mycoses


Subcutaneous mycoses


Candidiasis


Thrush


Systemic Candidiasis


Cutaneous Mycoses

Dermatomycoses


Known as tinea or ringworm


- atheletes foot is tinea pedis


** metabolizes Keratin


treated with topical micanazole

Subcutaneous Mycoses

More severe the cutaneous


causes sporotrichosis


- it infects wounds and grows nodules along lymph vessels.


Treated with potassium Iodide (KI)

Candidiasis

*usually caused by the suppression of competing bacteria b/c of antibiotics.


*occur in skin and mucous membranes of genital tract and mouth.



Thrush

Candida albicans


yeast infection of the mouth

systemic candidiasis

in immunocompromised individuals

Parasitic skin infections

Scabies


Periculosis or lice

Bacterial eye infections

Conjuntivitis


Opthalma neonotorium


Chlamydia trachomonosis


Keratitis- herpectic and acanthemoeba

conjunctivitis

pink eye


casused my haemophilus influenza

Opthalmia Neonatorium

Caused by N. Gonorrhoeae


Passed on to babies in birth canal


silver nitrate eye drops



TETRACYLINE, ERYTHROMICIN, NITRATE DROPD



Chlamydia Trachomatis

causes inclusion conjuctivitis


transmitted via birth canal


can be caught when swimming


TETRACYLINE

Keratitis

inflammation/infection of cornea


Bacterial Asperilligus


transmitted through dirty water


Acanthomoeba keratitis can be caused by dirty contacts.


Herpectic Keratitis caused by HSV 1


-blindness


-trifluridine