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142 Cards in this Set
- Front
- Back
Muscles contract and remain
-paralyses of resp. muscles |
c. tetani
|
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Muscles can't contract
-flaccid paralysis |
c. botulinum
|
|
headache
stiff neck convulsions |
N. meningitits
|
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high fever
delirum comma |
N. meningitis - if left untreated
|
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lesion may develop- tubercle
-cough -greenish or bloody sputum -fever -chest pain |
m. tuberculosis
|
|
produce greenish pigment ( on wounds etc)
|
PSEUDOMONAS AERUGINOSA
|
|
conjunctivitis
-conjunctiva (inner lid) inflamed. |
eye infection/ chlamydia trachomatis
|
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secondary bacterial infection can cause corneal damage and blindness
|
eye infection/ chlamydia trachomatis
|
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In males - non gonococcal urethritis
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Genital infection/ Chlamydia trachomatis
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In females- cervicites, endometritis, pelvic inflammatory disease.
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Genital infection/ Chlamydia trachomatis
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deprivation of body fluids and electrolytes
|
E coli
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Some strains make toxins that kill cells in colon producing an ulcer
|
e. coli
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damages ribosomes
bloody diarrhea kidney damage ( mostly in children) |
e. coli/ 0157 strain
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|
pyoderma( impetigo)
burning itchy patches that break and form yellow crust |
Grp. A strep / skin infection
|
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spread to underlying skin layers- more invasive
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Erysipelos/ Grp. A strep/ skin infections
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redness
swelling pain pus filled nodules on tonsils |
Grp. A strep/ Throat Infection
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Grp. A strep /throat infections can cause what 2 diseases due to complications
|
Scarlet Fever
Rheumatic Fever |
|
due to Erythrogenic toxin
|
Scarlet Fever
|
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bright red rash over face trunk arms and legs
|
scarlet fever
|
|
fever
inflammation and injury |
rheumatic fever
|
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fluid spreads > out lungs
-cough, rust colored sputum -abnormal breathing sounds may be heard |
Grp. D strep/ Step pneumonia
|
|
abcess ( lesion called furuncle)
-causes most wound infections -furuncles (if) join dev. carbuncle |
S. aureus
|
|
What two diseases does staph cause due to its toxins
|
Food poisoning
Toxic shock syndrome |
|
cramping
nausea vomiting diarrhea within 2-6 HRS. recovery- 24 hrs |
Food poisoning/ staph
|
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fever
vomiting rash |
Toxic shock syndrome
|
|
thrush
vaginal yeast systemic candidiasis |
C. Albicans ( fungal)
|
|
painful vaginitis(itch & burn)
-frothy discharge |
trichomonas vaginalis
|
|
in males affects urethra but rarely causes symptoms
|
trichomonas vaginalis
|
|
vesicles on genitals
-urethrits -painful urination -cervicitis -itching |
HSV 2
|
|
jaundice
-liver tender and enlarged -cause cirrhosis and liver cancer |
Hepatitis B
|
|
sore throat
-muscle ache -rash -enlarged lymph nodes |
Aids/ HIVe
|
|
fever
-headache -sore throat -muscle ache -cough ( little or no sputum) May cause pneumonia -uncommon |
Influenza
|
|
gram + spore forming rod
|
clostridium
|
|
gram - cocci
|
neisseria
|
|
rods retain primary dye -
-R acid fast rods - grow slowly - have wax layer , very resistant to phagocytosis, drying , germicides |
mycobacteria
|
|
gram - rod
|
pseudomonas aeruginosa
|
|
gram - cell wall
|
chlamydia trachomatis
|
|
gram - rod
|
e. coli
|
|
enteric pathogesn
|
e. coli
|
|
Name 2
Gram + cocci |
Staph and strep
|
|
have two types b hemolysins
and alphas hemolysins |
Streptococcus
|
|
Rapid lyses of bl cells, clear Zone
|
B hemolysins (strep)
|
|
Greening of blood (grp.d)
|
strep
Alpha hemolysins |
|
strep name two grps.
|
Grp a
grp d |
|
commonly seen on skin and mucous membranes
|
staph
|
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considered to be th most resistant of all non spore forming pathogens
|
staph
|
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resists drying, many disinfectants and antibiotics
- causes many nosocomial infections |
staph
|
|
protozoan infection
|
trichomonas vaginalis
|
|
an rna virus
|
Influenza
|
|
antitoxin given name 2
|
c. tetani and c. botulinum
|
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vaccine DpT- tetanus toxoid
|
c. tetani
|
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penicillan, rifampin
|
n. meningitis (vaccine yes)
|
|
RIFAMPIN AND STREPTOMYCIN
|
M. tuberculosis
|
|
combination therapy
|
pseudomonas aeruginosa
|
|
tetracycline and erythromycin
|
eye infection/genital infection
|
|
restore fluids/cephalosporin
|
e.coli
|
|
penicillan
-tetracycline |
Grp. A strep
|
|
Penicillan
|
Grp. D strep
|
|
antiviotics
drain abcesses penicillans and vancomysin |
s. aureus
|
|
topical antifungal ointment
-fluconazole -amphotericin b |
c. albicans
|
|
flagyl
|
trichomonas vaginalis
|
|
acyclovirq
|
HSV one and two
|
|
azt and DDI
Inhibitors |
Aids/HIV
|
|
Vaccine available
amantadine -type a neuraminidas inhibitors- relenza (inhaled) tamiflu(oral |
influenza
|
|
has anitgens that place into 3 grps.
|
influenza
|
|
what virus has two spikes? Name spikes ?
|
Influenza
1.Hemagluttin spike 2.Neuraminidase Spike |
|
Virus attach to epithelial cell and enter is called and what virus
|
Hemagluttin spike/influenza
|
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antigenic drift occurs in what virus?
|
influenza
|
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breaks bond between virus and hosts cells so it cna tattach to nearby cells
|
Neuraminidase spike/Influenza
|
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two diff. strains exchange dna makin new H and N protein. and in what virus
|
Antigenic drift/influenza
|
|
Transmitted by inhaled aerosols
|
Influenza
|
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can cause pneumonia -most deaths due to secondary bacterial infection
|
influenza
|
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found in
-blood -semun -vaginal fluid -feces |
Hep B
|
|
enters body -> break in skin or mucous membranes
|
HEP B
|
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multiplies in liver
|
HEP B
|
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The livers excretion of bile into intestines is disrupted and the pigment )______ found in bile enters bloodstream causing jaudnice? What disease?
|
bilirubin
HEP B |
|
found in
-blood -semun -vaginal fluid |
HIV/Aids
|
|
Has 2 RNA strands
|
HIV
|
|
Spread > direct contact- sexual activity, blood products
|
HIV
|
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HIV- It uses its __ ___ to attach to receptors on b and t cells, macrophages, t helper cells with the ___ anitigen as its main target
|
Envelope spikes
CD4` |
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HIV- the virus uses its envelope spike to bind to the CD4 and the _ receptor of the host cell
|
CCR5
|
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HIV/ The virus enters and rele3ases its _______
|
RNA
|
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HIV/ _______ _______ changes its RNA into DNA and the viral dna is incorporated into the host dna
|
reverse transcriptae
|
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HIV/ Viral __ and proteins r made and new viruses r assembled and released
|
mRNA
|
|
Blood tests detect igs
no vaccine |
Hiv/aids
|
|
can cause
pneumoni -tb -cancer of bl and lymph vess.(karpois sarcome) -yeast infections |
Aids
|
|
block dna prod and synthesis-
|
azt/ddi for aids/hiv
|
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transmitted bycontaminated sputum/droplets from coughing sneezing
|
M tuberculosis
|
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Enters hos > resp. tract
|
m. tuberculosis
|
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resides in the lungs
|
M. tuberculosis
|
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transmitted by contaminated sputum/droplets from coughing and sneezing
|
m.tuberculosis
|
|
enters hos > resp. tract
|
m. tuberculosis
|
|
resides in the lungs
|
M tuberculosis
|
|
amcrophages phagocytize
|
m. tuberculosis
|
|
Most people recover more or less completely
|
m. tuberculosis
|
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the bacillus may spread to other body parts
|
m. tuberculosis
|
|
found in soil and water
|
pseudomonas aeruginosa
|
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resistant to antibiotics, soaps, disinfectants, drugs, drying
|
pseudomonas aeruginosa
|
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freq. contaminant of humidifiers,ventilatiors,iv solutions,disinfected instruments
|
pseudomonas aeruginosa
|
|
very opportunistic organism
|
pseudomonas aeruginosa
|
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produces exotoxins, a resistant slime layer and various enzymes that break down host tissues
|
pseudomonas aeruginosa
|
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10*20 % of nosocomial infections
|
pseudomonas aeruginosa
|
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lives in naso pharynx and skin
|
Grp a strep
|
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can cause a flesh eating bacteria
|
Grp. A strep
|
|
results when microve multiplies in tonsils or pahryngeal mucous membranes
|
Throat infectio
|
|
cused by a strain that carries a prophage coding for a toin called erythrogenic toxin
|
scarlet fever
|
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may occur when we make ig's against strep antigens by certain strains.
|
rheumatic fever
|
|
igs may cross react with simila antigins found in th e heart and joints causing inflammation and injury. may be fatal when it damages heart valves
|
Rheumatic fever
|
|
causes 60% of bacterial pneumonia
|
Grp. D strep
|
|
Transmitted > resp. drop
|
Grp. D strep
|
|
If microbe enters lungs the inflammatory response releases lrg. amounts of fluid to.
|
Grp D strep
|
|
Because of their capsule they escape phagocytosis
|
Grp D strep
|
|
Causes mos deaths per year in us than any vaccine preventable disease
|
Grp. D strep
|
|
normall found in
mouth- genitals lrg intest skin 20% of pop |
c. albicans
|
|
risk factprs:
pill diabetes antibiotic therapy |
yeast infections
|
|
if enters blood , results r grave ( heart and brain)
|
systemic candidiasis
|
|
flagellate protozoan causes trichononiasis and is sex transmitted
|
Trichomonas vaginalis
|
|
called lock jaw
|
c. tetani
|
|
spores from soil enter puncture wounds, burns, etc.
|
C. Tetani
|
|
Produces a tetanus toxin______ which binds to neurons and prevents them from releasing inhibitory nerotransmitters that cause muscles to relax
|
tetanospasm/ c. tetani
|
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the toxin enter the neurons and prevents the release of _______ which causes muscle contraction
|
acetylcholine/ c. botulinum
|
|
most infections occur late winter early spring
|
n. menengitits
|
|
Transmitted > contaminated air droplets
|
n. meningitis
|
|
Uses its pili to attach to resp. tract
|
N, meningitis
|
|
Those that move from mucous membranes and enter blood stream penetrate the menenges causing sumptoms which is due 2 pressure swueezing brain against the skull
|
n. meningitis
|
|
The microbe has an IGA protease for production
|
N. Meningitis
|
|
has endotoxin
|
N. meningitis
|
|
the mos frequent cause in young chilren is a gram-cocobacillus hemophilus influenza
|
n. meningitis
|
|
transmitted sxually
|
genital infection
|
|
can block tubes causing sterility and ectopic pregnancy
|
genital infection
|
|
the ones with toxin producing plasmid genes cause diarhheal disese from
|
e.coli
|
|
found in contaminate food and water
|
e.coli
|
|
found in meat
|
the 0157 strain/e.coli
|
|
a strain of e. coli is more serious because it causes more fluid loss
|
vibrio cholera from cholera
|
|
toxins act on the nerves of intestines causing symptome
|
food poisoning
|
|
super absorbant tampons may cause toxin production, superantigen by a strain
|
toxic shock syndrome`
|
|
obligate parasites
|
chlamydia trachomatis
|
|
alternate between 2 stages?
|
chlamydia trachomatis
|
|
sm. inactive infectious form
|
elementary body/chlamydia trachomatis
|
|
lrger active non infectious form
|
reticulate body?chlamydia trachomatis
|
|
from contaminated fingers, fomites, flies etc
|
Eye infection
|
|
wound infections caused by _______r the most common nosocomial infections.
|
staph
|