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6 Cards in this Set
- Front
- Back
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DIPHENHYDRAMINE
Class/ MOA |
Class
Antihistamine; anticholinergic. Mechanism of Action Blocks cellular histamine receptors; decreases vasodilatation; decreases motion sickness. Reverses extrapyramidal reactions |
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DIPHENHYDRAMINE
I/CI |
Indications
Symptomatic relief of allergies, allergic reactions, anaphylaxis, acute dystonic reactions (phenothiazines). Blood administration reactions; used for motion sickness, hay fever. Contraindications Asthma, glaucoma, pregnancy, hypertension, narrow angle glaucoma, infants, patients taking Monoamine Oxidase Inhibitors |
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DIPHENHYDRAMINE
AR/DI |
Adverse Reactions
Sedation, hypotension, seizures, visual disturbances, vomiting, urinary retention, palpitations, dysrhythmias, dry mouth and throat, paradoxical CNS excitation in children. Drug Interactions Potentates effects of alcohol and other anticholinergics, may inhibit corticosteroid activity, MAOIs prolong anticholinergic effects of diphenhydramine. |
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DIPHENHYDRAMINE
Doseages and admin |
Dosage and Administration
Adult: 25 - 50 mg IM or IV or P.O. Pediatric: 1-2 mg/kg IV, IO slowly or IM. If given PO: 5 mg./ kg./ 24 hours. |
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DIPHENHYDRAMINE
DOA/ Specials |
Duration of Action
Onset: 15-30 minutes. Peak effect: 1 hour. Duration: 3-12 hours. Special Considerations Not used in infants or in pregnancy: Category B. If used in anaphylaxis, will be in conjunction with epinephrine, steroids. |
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DIPHENHYDRAMINE
how supplied |
How Supplied
Tablet: 25, 50 mg; Capsules: 25, 50 mg. 50 or 100 mg prefilled syringes, vials (IV or IM); elixir 12.5 mg/5 ml. |
