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6 Cards in this Set
- Front
- Back
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Carb digestion/absorp
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-Amylase in mouth, small intestine (from pancreas) hydrolyze to disaccharides
-further hydrolyzed to monosaccharides by small intestinal epithelial enzymes -absorbed into portal blood |
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SGLT transporter
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-hexose absorption in small intestine
-sodium actively transported out of enterocyte, then Na-glucose cotransporter moves Na into cell along concentration gradient and glucose follows -deficiency leads to glucose/galactose malabsorption |
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Protein digestion
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-Pepsin in stomach (activated by HCl) digests collagen
-Trypsin, chymotrypsin, carboxypeptidase, elastase in small intestine (require enterokinase) hydrolyze to aa -some peptidase in brush border and mucosal cells |
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protein absorption
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-Na, Cl and H cotransporters
-fast in duodenum and jejunum, slow in ileum |
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Lipid digestion
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Pancreatic lipase in duodenum (aided by colipase), cholesterol esterase, phospholipase A2
~lipase from tongue, stomach -requires emulsification by bile salts and lecithin in small intestine -inhibited by acid -TG hydrolyzed to fa |
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Lipid absorption
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-Small FA absorbed into portal blood
-Larger FA reesterified to TG and coated to form chylomicron which enter lymphatics |
