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46 Cards in this Set
- Front
- Back
What are the fxn of the digestive system?
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transport , digestion, and absorption of ingested nutrietns
barrier between internal and external enviroment protection agianst pathogens endocrine function intrinsic factor removal of heptatic excretory products reabsoprtion of secreted fluid and electrolytes |
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What physical parts does the digetive system have which protect against pathogens?
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acid secretion, peristalis, IgA, presence of secondary lymphatic tissue, tonsils, peyer's patch, appendix
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What are the endocrine fxn of the digestive system?
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gastrin, CCK, GLP1, secretin, ghrelin
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What products does the heptic system excrete?
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drugs
Cholesterol |
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What fluids does the digestive system reabsorb?
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fluids and electrolytes
1-2 L of saliva a day |
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How long is the digestive system?
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9 meters in length
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What does the salivary glands secrete?
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fluid containing ptyalin
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Fxn of saliva
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- lubricate food
- facilitates speech |
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saliva is
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hypotonic
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PSNS __________ secretions
SNS ___________ secretions |
increases
decreases |
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The largest salivary gland is ___________ and can be effected by __________
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paritods
Mumps virus |
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Dysphagia
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difficultly with swallowing
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What initiates swallowing?
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Bolus of food
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What fluids are secreted by stomach fluids?
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Gastrin, HCL, pepsinogen, mucus, ghrelin
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Gastrin
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acid secretion- they go up with a meal- cause pH to change and HCL goes up
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Pepsinogen
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secreted as inactive forms- zimogens (enzymes)
they break down complex molecules becomes pepsin and then breaks down protiens - facilititates breakdown of protiens |
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HCL
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bacterialcial or bacteriosidic
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alcohol
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rapidly absorbed in the stomach
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the fxn of mucus
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severes as a barrier
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ghrelin
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a new hormone secreted by the stomach - may be involved in satiety
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H. plyloria
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causes ulcers
contributes to urease gram negative spiral shaped bacterium |
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Peptiv ulcers
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5 million Americans
50 percent of adults over 50 colonized with H pylori |
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H plyori fxn
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sustains gastrin secretion resulitng in more H= secretion
(2) secretes toxins or enzymes that damage the mucosa |
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Detecting H plyori
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breath test
c14 ura ingested urease from H pylori converts this into c14o2 gets into blood stream and can be measured in breath |
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acid secretionbstimulated by
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gastin
acetylcholine histamine |
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As acid accumulates
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reduces gastrin secretion
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Zollinger-Ellison Syndrome
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too much gastrin
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What nerver affects the stomach?
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vagus- which terminates in the medulla at the Emetic center
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Where does the emetic center receive information from?
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cortical centers and the vestibular apparatus (this center detects motion)
recieves input from the chemoreceptro trigger zone |
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Ipecac
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drug that cause emesis
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Vomiting can cause ....
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dehydration, alkalosis, and hypokalemia
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Antiemetics are....
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scopolamine
antihistamines dopamine antagonist |
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Chyme
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food in the stomach
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chyle
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food in the small intestines
first thing to neutralize the H+ |
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H+ stimulates
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secretin relase and therefore causing secretion of pancreatic fluid which is rich in bicarbonate.
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Explain digestion
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amino acids and fatty acids in chlye stimulate the secretion of CCK- this caues the pancreas to secrete digestive enzymes (zymogens) and the Gall Bladder to contract. Acetylcholine fromt eh vagus also participates in enzyme secretion. Together secretion and CCK synergizes.
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Pancritiis usually caused by
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alcohol and gallstones
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pancreatic secretions enter the ___________ via the ____________
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small intestines
pancreatic duct |
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What is the ampulla of Vater?
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pacreatic distal end that converges with the bile duct at the ampulla of Vater
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What is the brush border of enterocytes?
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enzymes are contained in villi (fingerlike projections) and breakdown nutrients into further elements, for example, simple sugars and amino acids
lactose 16 intolerance is a result of the absence of one of these |
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Where do nutrients go to from the intestines?
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portal circulation
most digested nutrients (amino acids and carboyhydrates) are dilvered to the liver via the portal circulation |
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Chylimicrons enter the circulation via
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lacteals (beginning of teh lymphatic drainage)
then enter the venous circulation via the thoracic duct |
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What happend at the terminla ileum?
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about 75% of bile salts are reabsorbed
B12 is absorded here |
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What happens if bile salts are not reclaimed by the liver?
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if they escape- they can cause pruritus and promblem in cirrhosis
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What happens in the large intestines?
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salt and water are absorbed
bacteria is here as well |
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What is the tumor marker for colon cancer ?
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relationship between serum carcinoembryonic antiger (CEA) levels
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