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26 Cards in this Set

  • Front
  • Back
What is the structure-function relationship in the G.I. tract?
Length and complexity of gut determined by ease of digestibility and processing of food
Short, simple gut = fast processing (carnivore)
What processes are under control in the digestive system?
Mechanical processing (smooth muscle contraction)
Secretion of gastric juices
Enzymatic breakdown
Absorption
What are the 2 ways in which digestion is controlled?
Neural and hormonal influences
Which parts of the nervous system control the digestive system?
Which parts of the nervous system control the digestive system?
Autonomic and enteric
Give some examples of digestive hormones
CCK, gastrin, histamine
What is the sympathetic nervous system responsible for?
Fight or flight response
Which parts of the autonomic nervous system correspond to the intrinsic and extrinsic parts of the gut?
Intrinsic - enteric NS
Extrinsic - Parasympathetic and sympathetic
Which part of the nervous system can reach the G.I. tract without communicating with the enteric NS?
Sympathetic NS
Which nerve connects the parasympathetic NS to the ENS?
Vagus (oesophagus to small intestine) and pelvic (large intestine)
What are pre-ganglionic fibres in the sympathetic nervous system?
Fibres from CNS to prevertebral ganglia (where synapse occurs e.g. coeliac ganglia)
What are post-ganglionic fibres in the sympathetic nervous system?
Fibres between prevertebral ganglia to effector organ
What are the neurotransmitters in the pre-ganglionic and post-ganglionic fibres?
Pre-ganglionic - acetylcholine
Post-ganglionic - noradrenaline
What is the difference between post-ganglionic fibres in the sympathetic and parasympathetic nervous systems?
Post-ganglionic fibres in the parasympathetic NS are enteric neurones because pre-ganglionic fibres synapse in the enteric NS
Where do pre-ganglionic fibres of the vagus nerve and the pelvic nerve arise from, respectively?
Vagus nerve - medulla
Pelvic nerve - S2 - S4
In the parasympathetic NS, which fibres are excitatory and inhibitory?
Pre-ganglionic - excitatory
Post-ganglionic - excitatory or inhibitory
What is the neurotransmitter of pre-ganglionic fibres of parasympathetic NS?
Acetylcholine
Which parts of the digestive system are innervated somatically?
Pharynx/oesophagus
External anal sphincter
For swallowing and defaecating
Which nerves control swallowing and defaecating?
Swallowing - vagus nerve
Defaecating - pudendal nerve
Does the enteric NS need CNS control?
Reflexes can operate independently of CNS
What does the enteric NS control?
Motility, fluid movement and blood flow
Where is the myenteric plexus found?
Between the outer longitudinal muscle and the inner circular muscle of muscularis propria layer
What are the 3 types of neurone found in the enteric NS?
Motor
Sensory
Interneurone
What is an interneurone?
The connection between motor and sensory neurones
Name 4 enteric neurotransmitters
Vasoactive intestinal peptide
Acetylcholine
Substance P
Nitric oxide
Can more than one neurotransmitter be found in a neurone?
Yes (record is 7)
Where is the submucous plexus found?
Between inner circular muscle and submucosa