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13 Cards in this Set

  • Front
  • Back
DM is a chronic d/o caused by:
1) Deficient insulin production
2) Insulin action in the body
DM causes:
Hyperglycemia
Type 1
Little or no insulin produced
Type 2
Defect in insulin production OR impairment of insulin receptors
Risk factors for type 2?
Race (latino americans, native americans, asian americans and pacific islanders are most at risk)
Consequences of decreased insulin?
- Glucose is not taken up by tissues -> increased synthesis of glucose by the liver
- protein synthesis is impairied (b.c the AA transport requires insuline)
- Metabolism of fats are altered -> release of ketone bodies
Increased levels of serum glucose lead to:
1) Pulling of fluid from interstitial fluid
2) Fluid loss through kidneys
3) Increased thirst
Increased secretion of glucose in urine
Consequences of decreased insulin?
- Glucose is not taken up by tissues -> increased synthesis of glucose by the liver
- protein synthesis is impairied (b.c the AA transport requires insuline)
- Metabolism of fats are altered -> release of ketone bodies
Meds that can exacerbate hyperglycemia?
Corticosteroids, Epinephrine and Growth Hormone
Increased levels of serum glucose lead to:
1) Pulling of fluid from interstitial fluid
2) Fluid loss through kidneys
3) Increased thirst
Increased secretion of glucose in urine
PT implications for diabetics?
Stress can increase Cortisol -> hyperglycemia
Meds that can exacerbate hyperglycemia?
Corticosteroids, Epinephrine and Growth Hormone
PT implications for diabetics?
Stress can increase Cortisol -> hyperglycemia