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102 Cards in this Set

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Before procedures:
OFF ASA for at least 5 days (plt fxn affected)
OFF Plavix for one week
OFF Lovenox for 24-48 hrs; does not necessarily affect PTT
STOP heparin 4-6 hrs prior; PTT must be < 40
Protamine can be used to counter heparin or lovenox
Coagulation correction:
heparin – stop for 3-6 hrs prior, or protamine IV in minutes; coumadin – vit K x 3 takes days, or FFP in minutes; aspirin – stop aspirin 1 wk, or plts in minutes
Thrombolysis treatment:
Always start tPA at 1 mg/hr; fibrinogen followed q8hrs along with H/H, platelets, and K+; if fibrinogen falls <150 cut infusion rate in ½; if it falls <100 stop infusion.TPA 0.5-1 mg/hr and heparinize, repeat angio in 12 hrs, coaxial dual infusion
Thrombolysis treatment: Indications
arterial graft thrombosis, native acute thrombosis, prior to percutaneous intervention, hemodialysis AVF or graft, venous thrombosis;
Thrombolysis treatment:absolute contraindications
active bleed, intracranial lesion (stroke, tumor, recent surgery), pregnant, nonviable limb
Thrombolysis treatment:favorable prognosis
if recent clot, good inflow/outflow, positioned in thrombus
Thrombolysis treatment: endpoints
endpoints – no lysis after 12 hours infusion, major complications, fibrinogen <100mg/dl
Thrombolysis treatment:success
90% for grafts and 75% for native
Thrombolysis treatment:Cx
major hemorrhage, distal embolization, pericatheter thrombosis
Treatment:Proximal subclavian stenosis:
carotid-subclavian bypass = 90-96% long term patency
Treatment:Common iliac stenosis:
PTA with stent placement (kissing stents if bilateral) = 80-90% at 4 yrs
Aortofem bypass = 90% at 5 yrs
ABI
ABI 0.5-0.9: claudication
ABI 0.2-0.4: rest pain
Reasons for hepatic venogram:
measure wedge pressure (often with balloon dilated), to perform carbon dioxide portography, to perform TIPS, to diagnose Bud Chiari.
methods of portal venography:
hepatic vein wedge via CO2, delayed SMA injection
TIPS: indications
portal HTN and variceal bleeding failed sclerotherapy, refractory ascites, refractory hepatic hydrothorax, Budd-Chiari
TIPS: absolute contraindications
severe R heart failure, liver failure (MELD >26)
TIPS: relative contraindications
PV thrombosis, hepatic encephalopathy, infection, vascular liver tumors, polycystic liver dz
TIPS: GOAL
portosystemic gradient < 12 mmHg, decompression of varices; patency 50% at 1 yr;
TIPS COMPLICATIONS
major complication early is intraperitoneal hemorrhage due to transcapsular needle puncture, hepatic encephalopathy, shunt thrombosis or stenosis, R heart failure, renal failure.
Normal portal vein - systemic vein pressure:
< 6 mm Hg; > 12 = risk of variceal bleeding;
PV thrombosis
idiopathic, HCC, panc CA, mets, post-op, coagulopathies, sepsis, pancreatitis, cirrhosis and portal HTN
PORTAL VEIN COLLATERALS
gastroesophageal, mesenteric, perisplenic, periumbilical, hemorrhoids;
findings in PV thrombosis
splenomegaly, portal collaterals (cavernous transformation), recanalized periumbilical vein or hepatofugal flow.
Types of biliary drains:
external, internal-external, and internal
2 major complications of PTC/PBD
percutaneous transhepatic cholangiography; percutaneous biliary drainage
(1) HA pseudoaneurysm (tampanode bile tract with balloon and coil artery) and (2) biliary sepsis (premed with abx)
Budd-Chiari:
HV thrombosis, tumor growth in HV and/or IVC (RCC, HCC, adrenal); spider web hepatic veins, IVC narrowing, stretched straight hepatic arteries
HCC: findings on angio
arterial-portal venous shunting and portal vein invasion and thrombosis are findings nearly pathognomonic for HCC; increased tumor vascularity is also noted;
Chemo embo for HCC
hepatic chemoembolization can be performed if tumor does not occupy >50-75% of liver; Hepatic arterial supply chiefly to tumor so can embolize without concern for infarct since most of hepatic supply is by portal vein. Use PVA particles, CTX, contrast, ethiodol. CT immed post-procedure.
HCC post embo syndrome
A condition that includes pain, nausea, vomiting and low-grade fever
Things to know prior to chemo embo HCC
Before TACE, must know if portal vein patent and direction of flow. Late phase celiac and SMA injection will give you the answer.
Liver chemo embo common tumors
HCC, neuroendocrine tumors, melanoma, sarcoma, colon
Porta Hepatis Biliary Obstruction:
Klatskins tumor, HCC, gallbladder CA, Metastatic LAD at porta hepatic, Mirizzis
Microaneurysma in Liver:
PAN, necrotizing angiitis secondary to drug abuse (methamphetamine), mycotic aneurysms
Axillosubclavian vein occlusion:
thoracic outlet obstruction (Paget-Schroetter syndrome) versus indwelling catheter
Thoracic Outlet obstruction:
exacerbated by shoulder abduction or Adson’s maneuver (hyperextend neck with head rotated to ipsilateral side and inspire deeply); may cause subclavian vein occlusion and/or subclavian artery occlusion/thrombosis (with emboli!)/aneurysm; causes include cervical rib, muscular habitus with enlargement of the anterior scalene muscle or pec minor, scalenus minimus muscle, anomalous 1st rib that narrows the costoclavicular space, healed fracture deformity of 1st rib or clavicle. Tx: surgical decompression with possible arterial embolectomy.
Lower GI Bleed:
diverticulosis most common, angiodysplasia, colon CA, polyps, IBD, rectal dz; blood pool study for screening; inject SMA, IMA, celiac; tx – gelfoam, vasopressin, coils (used less due to less collaterals); vasopressin 0.2 U/min x 20 min, repeat angio, 0.4 U/min x 20 min if still bleeding, repeat angio, embolization or surgery if still bleeding, when bleeding controlled continue for another 12 hrs and then slow taper over 12-24 hrs (persistent abdominal pain may indicate ischemia); recurrent bleeding occurs in 40% patients. Vasopressin NOT used for UGI bleed; contraindication to vasopressin = CAD, CV disease, severe HTN.
Mesenteric ischemia:
acute or chronic, nonocclusive most common – atherosclerosis and low flow state, arterial occlusion (embolus, thrombus, dissection, vasculitis), mechanical (hernia, volvulus, intussusception); filling defects or occlusion, diffuse vasospasm; tx – thrombolysis if acute and no bowel ischemia, surgery if bowel ischemia, nonocclusive use papaverine IA 25-50 mg/hr.
Right arch with mirror image branching:
98% association with CHD (TOF and Truncus)
Takayasu’s arteritis:
most pts < 30 and females, THE classic large vessel arteritis; pathologically indistinguishable from giant cell arteritis, but the latter affects medium-size arteries, typically ECA branch such as superficial temporal artery; stenoses of arch vessels most common, stenosis and occlusion of aorta, thickening of aortic wall, PA involvement in 50%, abd aortic coarctation and RAS, aneurysms.
Giant cell arteritis:
older pts > 50, dx by bx temporal artery, involves ECA branches; aorta and proximal brachiocephalic branches usually spared; may have subclavian, axillary, brachial involvement in 15%.
SVC Syndrome:
Most common cause is bronchogenic carcinoma in USA. Other causes can include long-term catheters or pacemaker leads, granulomatous mediastinitis, radiation-induced fibrosing mediastinitis (this case); Radiation therapy may be considered first line for malignant SVCS; for palliation may perform thrombolysis and stenting; may have downhill varices
Hypothenar hammer syndrome:
occlusion or pseudoaneurysm formation of ulnar artery as it crosses over hamate from repetitive trauma, can result in distal embolic occlusions, Raynaud’s phenomenon, improves with priscoline. peripheral vasodilator
Subclavian steal syndrome:
narrowed or occluded subclavian artery proximal to origin of vertebral; retrograde flow in vertebral, more common in L, caused by atherosclerosis (#1), also trauma, thoracic outlet syndrome, vasculitis, extrinsic tumor compression, radiation; most are asx but can get vertebrobasilar insufficiency (ataxia) or arm claudication.
Splenic artery aneurysm:
Most common aneurysm of visceral arteries; next in abd after AAA and iliacs; Females 4:1. Multiparity and portal htn risk factors. Preg increases rx risk; Tx rec’d when > 2 cm size, women who may become preg or inflamm etiology – can embolize or stent graft; Need prox and distal embo to prev collateral filling. Other options incl surg ligation or splenectomy; Complications of embolization include splenic infarction, embolization of other arteries, abscess formation, incomplete occlusion, and recanalization.
Causes of popliteal artery stenosis or occlusion:
atheroscerosis, cystic adventitial dz, thromboemb
popliteal aneurysm, popliteal entrapment, posterior knee dislocation/relocation
Popliteal artery aneurysm:
Diffuse or focal enlargement of the popliteal artery with thrombosis; sx of distal ischemia may be secondary to emboli (20%) or more commonly thrombosis (40%). Significant % are bilateral. Assoc with aneurysm elsewhere (usually AAA or common femoral artery aneurysm); Rupture is very uncommon (<5%); tx is surgical resection with bypass
Popliteal artery entrapment:
young athletes, narrowing or occlusion on plantar flexion.
Buerger’s dz:
thromboangiitis obliterans, Inflammatory arteritis of unknown etiology affecting medium size arteries of upper and lower extremities ; male smoker 20-40 y/o, claudication, calf and foot vessels most common, Multiple abrupt segmental occlusions of the small and medium-sized vessels; background of otherwise relatively normal vasculature; Hallmark feature is distinctive CORKSCREW collaterals
IVC filters:
contraindication or failure or complication of anticoagulation; Bird’s nest for mega cava > 28mm up to 40mm, Simon nitinol filter (9F system) may be placed via brachial vein!; Standard Greenfield filter is a 14F system; IVC gram to document patency and level of renal veins; place below renal veins; suprarenal if infrarenal clot or pregnancy with IVC compression; duplication IVCs may need filter in each; retroaortic or circumaortic LRV – place below most inferior renal vein; if no room infrarenal, can do bilateral iliac vein filters.
Bronchial artery embolization:
Massive hemoptysis = 300 cc/day; bronchial artery angiogram shows tortuous tangle of vessels (neovasculairy 2o inflammation) vessels…active extrav very rare; originate from descending aorta at T5-6; spinal arteries may airse from bronchial arteries!!!; typically use polyvinyl alcohol.
Uterine artery embolization
Effective in reducing menorrhagia as well as pressure symptoms related to the bulky fibroids in more than 90% of patients; Selectively embolizing the uterine arteries with polyvinyl alcohol particles bilaterally; Ovarian artery collaterals prevent uterine infarct; Embolization may play a role in the management of uncontrolled post-partum hemorrhage using absorbable Gelfoam pledgets so that the uterine arteries will eventually recanalize, leaving open the possibility of future pregnancies.
Thoracic aortic aneurysm:
atherosclerosis – 90% fusiform, desc aorta more common, rupture uncommon if <5cm; cystic medial necrosis – HTN, Marfan, Ehlers-Danlos, sinus of valsalva aneurysm (tulip bulb) asc aorta, dissection common, calcs rare; syphilis – asymmetric, saccular, tree bark calcs common; mycotic – most are saccular at asc aorta or isthmus, perianeurysmal inflammation, immunocompromised, IVDA, endocarditis, postsurgical; posttraumatic pseudoaneurysm; aortitis – Takayasu’s, giant cell arteritis, CVD; true aneurysm usu fusiform, false aneurysms (posttraumatic, mycotic, postsurgical) usu saccular.
Aortic dissection:
chest or back pain, aortic insufficiency, BP discrepancy between extremities; causes – HTN, Marfan, Ehlers-Danlos, coarctation, bicuspid valve, pregnancy, trauma; Stanford A – asc aortic involvement, surgical tx, beware of pericardial tamponade, coronary artery occlusion, aortic insufficiency; Stanford B – desc aorta only, medical tx; intimal flap, displaced aortic calcs, delayed opacification of false lumen, compression of true lumen by false lumen, occlusion of branch vessels, abnormal catheter position; false lumen larger and slower flow and anterolateral in asc aorta and posterolateral in desc aorta.
Traumatic aortic injury:
aortic isthmus 95%, aortic root, hiatus; CXR – wide mediastinum, loss of aortic contour, L apical cap, NGT displaced to R, L bronchus displaced down, high rib fxs, hemothorax; CT – any mediastinal hematoma should get angio; angio – intimal tear (linear filling defect, irregularity of aortic contour), pseudoaneurysm, ductus diverticulum is smooth and broad-based.
AAA:
90% intrarenal, >3cm, increased risk or rupture when >5cm, assoc with popliteal aneurysms; Complications – rupture, aortocaval fistula, aortoenteric fistula, distal embolization, infection.
Endoleaks:
type 2 most common, filling of aneurysmal sac via IMA or lumbar branches.
Abdominal aortic coarctation:
young adults or children; congenital – coarctation, Williams syndrome, rubella, NF; acquired – Takayasu’s, FMD, radiation; segmental most common, usu involves renal arteries.
Williams syndrome:
supravalvular aortic stenosis, peripheral PA stenosis, diffuse coarctation of abdominal aorta and stenosis of visceral branches.
Aortoiliac occlusive disease:
Leriche syndrome in men – buttocks claudication, impotence, decreased femoral pulses; collaterals – internal mammary -> EIA via sup and inf epigastrics, IMA -> IIA via hemorrhoidal, intercostal/lumbar -> EIA via deep circumflex iliac, intercostal/lumbar -> IIA via iliolumbar and gluteals.
Mesenteric collaterals:
celiac to SMA – arc of Buehler, pancreaticoduodenal arcade; SMA to IMA – middle colic -> L colic, arc of Riolan, marginal artery of Drummond; IMA to IIA – via superior hemorrhoidal; rectal arcades – superior rectal from IMA, middle rectal from IIA, inferior rectal from pudendal.
Median arcuate ligament syndrome:
occlusion of proximal celiac artery from median arcuate ligament, accentuated on expiration, best detected on lateral projection.
UGIB:
gastritis most common, PUD, varices, MW tear; LGA > GDA; tx – vasopressin, gelfoam, PVA or coils for major arterial injury; rich collateral supply.
Angiodysplasia:
cecum/R colon, vascular tuft on antimesenteric border, early or persistent draining vein, active bleeding usu not seen.
RAS:
atherosclerosis > FMD, NF, arteritis (Takayasu’s, PAN, abd aortic coarctation); atherosclerosis – older pts, usu involves proximal artery, ostial stenosis poor PTA response (50%), mid RA stenosis 80% response, PTA to control HTN or preserve renal function; FMD – medial fibroplasia most common, mid and distal renal > ICA or vertebrals, string of beads, excellent response to PTA, most common cause of RAS in children, spontaneous RA dissection.
RA aneursym
FMD and atherosclerosis common, NF, AML, LAM; intraparenchymal – PAN, speed kidney.
RVT:
children – dehydration, sepsis, maternal DM, Wilms; adults – membranous glomerulonephritis, CVD, DM, trauma, thrombophlebitis, RCC.
PA gram:
indications – PE, PAH, pseudoaneurysm (trauma or iatrogenic, tx coils), AVM (assoc with OWR, feeding artery draining vein, tx coils); pacer required if LBBB, measure PA pressures (nl PAsys<30mmHg); Cx – acute R heart failure, arrhythmia, death, no absolute contraindications; PE indications – intermediate or indeterminate VQ scan, low prob with high clinical suspicion, contraindication to anticoagulation; acute PE – intraluminal filling defect, tram-tracking of contrast, abrupt cutoff, missing vessels, no collaterals; chronic PE – eccentric filling defects (muralized), smooth cutoffs, missing vessels, synechia or webs, collaterals
LE atherosclerotic occlusive dz:
sx – pain, pallor, pulselessness, paresthesias, paralysis; usu symmetric at bifurcations, SFA > iliac > tibial > pop > CFA; significant stenosis - >50% narrowing, collaterals, gradient > 10mmHg.
LE atherosclerotic aneurysmal dz:
pop a most common, bilateral in 50%, assoc with AAA; pop > iliac > femoral; distal embolization and/or thrombosis.
Arterial thomboembolism:
cardiac mural thrombus (LV aneurysm, afib, MI), aneurysms, iatrogenic, paradoxical (DVT and R-L shunt); emboli usu lodge at bifurcations, no collaterals, filling defects with menisci.
May-Thurner syndrome:
R common iliac artery compresses L common iliac vein -> DVT
UE dz:
atherosclerosis, vasculitis, emboli, trauma, iatrogenic, radiation, thoracic outlet syndrome – compression of brachial plexus or subclavian vessels, seen with hyperabduction, may see subtle subclavian artery aneurysm, tx is surgical if mechanical compression (e.g. cervical rib)
Trauma indications for angio.
any trauma with abnormal pulse exam; all pts with posterior knee dislocations should get arteriography.
Aneurysm:
atherosclerosis – abd aorta most common, desc thoracic aorta, peripheral vasculature (popliteal > iliac > femoral); infection (mycotic) – bacterial, syphilus; inflammation – Takayasu’s, giant cell arteritis, polyarteritis nodosa; congenital – Marfan, Ehlers-Danlos, FMD, NF
Ischemia:
arterial – dissection, embolus, thrombosis, thrombosed aneurysm, vasculitis, extrinsic compression, drugs; venous – thrombosis (phlegmasia cerulea dolens); low flow – hypovolemia, shock, hypoperfusion
Peripheral vascular disease:
atherosclerosis (occlusive, aneurysmal, small vessel in diabetics), embolic disease (thromboembolic, cholesterol emboli, plaque emboli), vasculitis, Buerger’s disease, medication
Emboli:
cardiac emboli – atrial fibrilliation, recent acute MI, ventricular aneurysm, bacterial endocarditis, cardiac tumor (myxoma); atherosclerotic emboli – aortoiliac plaque, aneurysm (AAA, popliteal); paradoxical emboli (R-L shunt) – DVT
Angiographic tumor features
BEDPAN – blush, encasement of arteries, displacement of arteries, puddling of contrast, arteriovenous shunting, neovascularity
Hypervascular lesions:
AVM – early draining vein, no mass effect; extensive collaterals – no early draining vein, no mass effect; tumor neovascularity – early draining vein in AV shunting, mass effect from tumor
Aortic enlargement:
aneurysm, dissection, poststenotic dilatation due to turbulence (coarctation, aortic valvular disease, sinus of valsalva aneurysm)
Aortic stenosis:
congenital – coarctation, pseudocoarctation, Williams syndrome (supravalvular aortic stenosis), rubella syndrome; aortitis – Takayasu’s disease (most common aortitis to cause stenosis); neurofibromatosis; radiation
Pulmonary artery stenosis:
Williams syndrome (infantile hypercalcemia), rubella syndrome, Takayasu’s, associated with CHD (esp tetralogy)
Hyperreninemic HTN:
decreased renal perfusion – atherosclerosis, FMD; renin-secreting tumors; renal compression – large intrarenal mass (cysts, tumors), subcapsular hemorrhage (Page kidney)
Renal tumors:
RCC -80% hypervascular, neovascularity, AV shunting, parasitization; AML – aneurysms, fat content; oncocytoma – spoke wheel in 30%, most hypovascular
Renal arterial aneurysm:
main artery aneurysm – FMD (common), atherosclerosis (common), NF, mycotic, trauma, congenital; distal intrarenal aneurysms – PAN, IVDA (septic), vasculitis (Wegener’s, CVD), traumatic pseudoaneurysm, radiation, amphetamine abuse (speed kidney)
Angio complications:
puncture site – hematoma, AVF, pseudoaneurysm, thrombosis, infection; contrast – renal failure, allergic reaction; catheter-related – thromboembolism, stroke, dissection; therapy-related – hemorrhage
Catheters:
high flow with sideholes for central vessels, low flow with endhole for selective vessels, higher flow rate with shorter catheter and larger diameter; pigtail – aorta, PA; Cobra – mesenteric, renal, contralateral iliac; Simmons – mesenteric, arch vessels; Tracker – coaxial subselection; straight – runoff.
Flow rates:
abd aorta/PA 20/40; celiac/SMA 6/60; renals 5/15; IMA 2/20; pelvis 10/40; one leg runoff 4/48; arch 30/60; CCA 8/10; ICA 6/8; ECA 2/4; vertebral 6/8; IVC 15/45.
Guidewires:
145 standard length, 0.018-0.038 inch, Newton J, Rosen, Amplatz, Bentson, Glide.
Pharmacologic:
vasodilator – papaverine 25-50 mg/hr for mesenteric ischemia, contraindicated with complete AV block; NTG 100 ug for peripheral spasm; vasoconstrictor – vasopressin 0.2-0.4 U/min for GI bleeding, contraindicated with CAD, HTN, arrhythmia.
Embolization:
indications – hemorrhage (GI, varices, traumatic organ, bronchial artery, tumor, post-op), vascular (AVM, AVF, pseudoaneurysm), pre-op devascularization (RCC, AVM, vascular bone mets), hepatic chemoembolization (palliative, gelfoam + ethiodol + chemotherapy for HCC, metastatic neuroendocrine tumor); beware of collaterals, use Tracker if possible; temporary agents – gelfoam pledgets (for UGIB, pelvic trauma, post-op); permanent agents – steel coils (large vessel, aneurysm, tumor), PVA (small particles for distal occlusion, tumors, bilateral UFE for fibroids), ethanol (solid organ necrosis, peripheral AVM); Cx – postembolization syndrome, infection, nontarget embolization
Angioplasty:
indications – claudication or rest pain, tissue loss, nonhealing wound, establish inflow for distal bypass graft, hemodialysis AVF or grafts; measure pressure gradients before and after PTA, heparinize after lesion crossed; priscoline 25 mg IA for vasospasm; balloon sized to adjacent normal artery except in aorta want to undersize, wire should always remain across lesion; large vessels/proximal lesions > small vessel/distal, stenoses > occlusions, short stenoses > long, isolated disease > multifocal, good inflow/outflow > poor; success for fem/pop PTA is 90% initial and 70% at 5 yrs, renals 95% initial with 95% at 5 yrs for FMD and 70-90% for atherosclerosis, ostial lesions poor prognosis; Cx – groin cx, distal embolization, rupture, renal infarction or failure.
Stents:
indications – unsuccessful PTA, recurrent stenosis, venous obstruction/thrombosis, TIPS, long segment stenosis, total occlusion, ineffective or unsuccessful PTA (residual stenosis > 30%, residual pressure gradient > 5 mmHg, large post-PTA dissection flap, hard calcified plaque), recurrent stenosis after PTA, ulcerated plaque, renal ostial lesions; success in iliac >90% 5 yr patency.
Foreign body retrieval:
snare, basket, retractable forceps; if in heart use pigtail to get out of heart then snare.
Urticaria
1. Discontinue injection if not completed. No treatment needed in most cases.
2. H1-receptor blocker: Benadryl 25-50mg PO/IM/IV or Vistaril 25-50mg PO/IM/IV. H2-receptor blocker may be added: Cimetidine 300mg PO/IV or Ranitidine 50mg PO/IV (diluted in 10ml D5W solution) slowly.
3. If severe or widely disseminated: Alpha agonist (arteriolar and venous constriction) - Epinephrine SC (1:1000) 0.1-0.3ml (=0.1-0.3mg) if no cardiac contraindications.
Facial or Laryngeal Edema
1. Epinephrine SC (1:1000) 0.1-0.3ml (=0.1-0.3mg) or, if hypotension evident, Epinephrine (1:10000) slowly IV 1.0ml (=0.1mg). Repeat as needed up to a maximum of 1mg.
2. O2 6-10liters/min (via mask).
3. If not responsive to therapy or obvious acute laryngeal edema, seek appropriate assistance (eg code team) and consider intubation.
Bronchospasm
1. O2 6-10liters/min (via mask).
2. Beta-agonist inhalers (bronchiolar dilators, such as metaproteronol, terbutaline, or albuterol)
3. Epinephrine SC (1:1000) 0.1-0.3ml (=0.1-0.3mg) or, if hypotension evident, Epinephrine (1:10000) slowly IV 1.0ml (=0.1mg). Repeat as needed up to a maximum of 1mg.
4. Alternatively, aminophylline 6mg/kg IV in D5W over 10-20 minutes (loading dose), the 0.4-1.0mg/kg/hr, as needed (caution: hypotension) or Terbutaline 0.25-0.5mg IM or SC.
5. Call for assistance (eg code team) for severe bronchospasm (or if O2 sat <88% persists).
Hypotension with Tachycardia
1. Legs elevated 60 degrees or more (preferred) or Trendelenburg position.
2. Monitor: EKG, pulse ox, BP.
3. O2 6-10liters/min (via mask).
4. Rapid administration of large volumes of normal saline.
5. If poorly responsive, Epinephrine (1:10000) slowly IV 1.0ml (=0.1mg). Repeat as needed up to a maximum of 1mg.
6. If still poorly responsive, transfer to ICU for further treatment.
Hypotension with Bradycardia (Vagal Reaction)
1. Monitor vital signs.
2. Legs elevated 60 degrees or more (preferred) or Trendelenburg position.
3. Secure airway: give O2 6-10liters/min (via mask).
4. Secure IV access: rapid fluid replacement with normal saline.
5. Atropine 0.6-1.0mg IV slowly.
6. Repeat atropine up to a total dose of 0.04mg/kg (2-3mg in adult).
Hypertension, Severe
1. Monitor EKG, pulse ox, BP.
2. Nitroglycerine 0.4mg tablet, sublingual (may repeat x 3), or, topical 2% ointment, apply 1 inch strip.
3. Sodium nitroprusside; solution must be further diluted with 5% Dextrose before infusion; must maintain proper monitoring for potential precipitous decreases in BP; review complete dosage and administration instructions prior to use; infusion pump necessary to titrate.
4. For pheochromocytoma – phentolamine 5.0mg (1.0mg in children) IV.
Seizures or Convulsions
1. O2 6-10liters/min (via mask).
2. Consider Valium 5mg or Versed 2.5mg IV.
3. If longer effect needed, obtain consultation; consider Dilantin infusion 15-18mg/kg at 50mg/min.
4. Careful monitoring of vital signs required.
5. Consider code team for intubation if needed.
Pulmonary Edema
1. Elevate torso; rotating tourniquets (venous compression).
2. O2 6-10liters/min (via mask).
3. Diuretics – Lasix 40mg IV, slow push.
4. Consider morphine. Corticosteroids optional.