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95 Cards in this Set
- Front
- Back
_______ are organic compounds formed from chains of amino acids
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Proteins
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________ are amino acids that cannot be manufactured by the human body
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Essential amino acids (EAAs)
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__________ are amino acids manufactured by the human body
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Nonessential amino acids (NEAAs)
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Each cell synthesizes proteins needed; cell must have access to ________
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all 20 amino acids
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_______ is the assortment of amino acids available to cells
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Amino acid pool
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Collection of amino acids that is constantly resupplied with _______ allows the cell to build proteins easily
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EAA’s
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Complex composition of protein understood through four structural levels:
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-primary structure
-secondary structure -tertiary structure -quaternary structure |
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________ determined by number, assortment, and sequence of amino acids in polypeptide chains
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Primary structure
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________ affects shape of amino acid chain; may be straight, folded or coiled
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Secondary structure
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_________ results when polypeptide chain is so coiled that loops of coil touch, forming strong bonds within chain itself
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Tertiary structure
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_______ is proteins containing more than one polypeptide chain
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Quaternary structure
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true/false:
If structure of protein changes, protein may not be able to perform original function |
true
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_______ is a change in shape of protein structures caused by heat, light, acids, alcohol, or mechanical actions
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Denatured
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_______ when the white of an uncooked egg is beaten; clear liquid turns white, foamy, and stiff
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proteins have been denatured
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Still a good source of amino acids; the shape of the chain has been changed
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denatured proteins
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_______ are controlled by mechanisms that keep our internal environment at the correct pH
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denaturation of body proteins
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Too _______ can lead to denaturation of proteins in the body; leaving them unable to perform their functions
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basic/acidic
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Site of only mechanical digestion of protein
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mouth
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Stomach mucosa secretes _________ and _________
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pepsinogen and hydrochloric acid (HCL)
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When pepsin activated by HCL process of protein hydrolysis begins resulting in _________________
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smaller-sized polypeptides
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________ and ________ continue hydrolysis of polypeptides
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Pancreatic and intestinal proteases
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Absorption of amino acids occurs through intestinal wall by competitive active transport requiring _________ as carrier
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vitamin B6
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Since amino acids are water soluble easily pass into ______
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blood stream
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Most protein functions result of protein ___________ in cells
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anabolism (sythesis)
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_______ have major role in regulation of protein metabolism
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Hormones
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Anabolism enhanced by effect of _________ and ________
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growth hormone (pituitary gland) and testosterone
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Hormones affecting protein catabolism are _______, are enhanced by __________
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glucocorticoids
adrenocorticorticotropic hormone (ACTH) |
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Catabolism begins in _____ cells through deamination
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liver
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________ a process through which an amino acid group breaks off from an amino acid molecule, resulting in molecules of ammonia and keto acid
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Deamination
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During deamination, most of the _______ converted to _______ by liver, later excreted in urine
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ammonia
urea |
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_________ either enters tricarboxylic acid (TCA) for energy or converted to glucose and fat (gluconeogenesis and lipogenesis)
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Keto acid
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_______ results in increased deamination by liver
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protein excess
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________:
-may result in high levels of keto acids, possibly ketosis -increased urea excreted by kidneys |
protein excess
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_______ and ______ could be stressed therefore general recommendation to consume no more than twice Recommended Dietary Allowance (RDA) for protein
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liver and kidneys
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_____ and _____- due to animal-derived proteins (high in saturated fat and cholesterol
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CAD and some cancers
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________- high protein intake increases calcium excretion
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Osteoporosis
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________ studies used to determine protein requirements throughout life cycle and to assign value to protein quality of foods to determine biologic value
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Nitrogen-balance
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_________ studies measurement of amount of nitrogen (N) entering body compared with amount excreted
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Nitrogen-balance
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__________: when more N retained in body than excreted
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Positive N balance
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_______ is used to form new cells for growth or healing
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Nitrogen
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_________ usually occurs among children, pregnant women, and individuals recovering from illness or injury
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positive nitrogen balance
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_________: when more N excreted than retained
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Negative nitrogen balance
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________ may be caused by aging, physical illness, extreme stress, starvation, surgery, or eating disorders.
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Negative nitrogen balance
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_______ needed to make proteins for muscle, tissue, bone formation, collagen, connective tissues, synthesis of scar tissue, and continual turnover of cells
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Amino acids
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_________ act as communicators to alert different parts of body to changes or to regulate function; some hormones are proteins
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Hormones
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______ are catalysts enabling chemical reactions or biologic changes to occur; enzymes are proteins
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Enzymes
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_______ depends on protein substances; several of the factors, such as fibrogen, are protein
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Blood clotting
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To defend body from foreign viruses and bacteria, proteins, or antibodies, are produced
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Immune system response
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Overall immunologic response depends on _______ formed within body
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proteins
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______ maintain body fluid and electrolyte balance
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Proteins
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As proteins circulate through body fluids, keeps water appropriately divided among 3 compartments:
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intravascular – within veins and arteries
intracellular –inside cells Interstitial –between cells |
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_______ can buffer effect of fluids to maintain safe acidic level in body fluids
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Blood proteins
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_______ of protein is ability of protein to regulate balance between acidic and base characteristics of body fluids
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Buffering effect
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_______ to protect shape of proteins to be able to perform usual functions
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Crucial function
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For individual cells, proteins act as ______, assisting nutrient movement in and out of cells
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pumps
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Transport of nutrients in blood by proteins such as _______
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lipoproteins
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Hemoglobin, special protein carrier, transports _______ in blood
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oxygen
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globin, another protein carrier, stores oxygen in _______
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muscles
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Proteins in foods categorized by ________
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EAAs
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_______ contains all nine essential amino acids
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Complete protein
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Animal-derived foods, including meat, poultry, fish, eggs, and most dairy products and soybeans- which are the only plant source that provides all _________
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9 essential AA’s
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_______ contains best balance and assortment of essential and nonessential amino acids for protein synthesis
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High quality protein
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_________ lack one or more of essential amino acids
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Incomplete protein
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________ the essential amino acid or amino acids that incomplete proteins lack
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Limiting amino acid
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By eating a combination of plant foods containing different EAAs, intake equals _______
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complete protein value
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Complementary proteins include:
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grains (e.g., wheat or rice) with legumes (e.g., kidney beans or chickpeas); and grains or legumes with small amounts of animal protein
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________ determines quality of food protein by measuring amount of N kept in body after digestion, absorption, and excretion
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Biologic value
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_________ measures amino acid composition of food as compared with reference protein; based on limiting amino acid
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Amino acid score
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___________ determines quality of food protein by comparing weight gain to protein intake
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Protein efficiency ration (PER)
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Recommended Dietary Allowance (RDA) for protein provides:
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-Sufficient intake of EAAs
-Enough total protein to provide amino groups to build new NEAAs -Other factors affecting protein RDA are age, gender, physiologic state, and sources of protein |
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RDA for protein is ______
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0.8g/kg (or 2.2 lbs)
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-Average adult man, RDA ___
-Average adult woman, RDA is _____ -Suggested levels for athletes _______ |
-58 to 63 g
-46 to 50 g -1 to 1.5 g/kg |
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Acceptable Macronutrient Distribution Ranges (AMDRs) suggest protein consumption range between ______% of energy intake
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10-35%
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To find what you weigh in kg:
To get RDA: |
weight in lbs/2.2
take what you get in kg x 0.8 |
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________consists of only plant foods; grains, legumes, fruits, vegetables, seeds, and nuts
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Vegan dietary pattern
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_________ consist of only plant foods plus dairy products; milk, cheese, yogurt, butter
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Lacto-vegetarian dietary pattern
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__________ consists of only plant foods plus dairy products and eggs
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Ovo-lacto vegetarian dietary pattern
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Health benefits of being a vegetarian:
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-reduced risk of obesity
-coronary artery disease (CAD) -type 2 diabetes mellitus -hypertension -gastrointestinal disorder -certain cancers |
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Benefits of Vegetarianism:
_______:religious belief in nonharming or protection of animal rights |
Spiritual rationale
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Benefits of Vegetarianism:
_________: financial cost of animal-related products compared to plant foods but costs to natural environment as well |
Economic and/or environmental benefits
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Vegan dietary pattern deficient in _______ and ______
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vitamins D and B12
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Representative of new semivegetarian dietary patterns evolving to decrease risk of chronic diet-related diseases
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contemporary vegetarianism
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______ dietary pattern of consumption of small amounts of fish
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Pesco-vegetarian
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_______ dietary pattern of consuming limited quantities of chicken
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Pollo-vegetarian
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________ an imbalanced nutrient and/or energy intake
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Malnutrition
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________: starvation caused by lack of protein, energy, or both; may result in marasmus and kwashiorkor
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Protein energy malnutrition (PEM)
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________: malnutrition caused by lack of energy intake
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Marasumus
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________: malnutrition caused by lack of protein while consuming adequate energy
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Kwahiorkor
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People with _____ are extremely thin, muscle mass is reduced, damage can occur to organs (heart, lungs), brain damage can result
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Marasumus
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People with _____ have swollen belly, full cheeks caused by edema, apathetic and have muscle weakness and poor growth
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Kwahiorkor
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Forces affecting developing malnutrition:
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-Biologic factors affect ability of body to use nutrients
-Economic factors limit ability to purchase food as affected by country’s economy and employment opportunities -Environmental factors directly affect food availability such as crop production and food safety |
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Regardless of overall wealth of nations, ______, ______, and _______ are malnutrition factors worldwide
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lack of education, social isolation, and effects of underemployment
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Health and economic support systems throughout life span can prevent ________
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malnutrition
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________ continual experience of under nutrition
(not enough food to eat) |
Chronic hunger
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Groups at Risk in North America:
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-Homeless individuals living in temporary sites
-Working poor, income barely covers basic expenses -Older adults -Hospital patients/chronic illnesses -Latrogenic malnutrition |