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31 Cards in this Set

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  • Back
What is intussusception?
Intestine telescoping upon itself (ileocolic is common)
What are the symptoms of intussusception?
6-12 months old
Sudden onset of severe intermittent abdominal pain
Gradual progression to lethargy
Bilious emesis
Currant jelly stools**
Sausage shaped mass in right side of colon
How is intussusception diagnosed and treated?
Diagnosed by ultrasound, air contrast enema, CT
Treatment with air contrast enema or surgery
What is the etiology of hemolytic uremic syndrome (HUS)?
Mostly in first 5 years of life
E. Coli 0157:H7 toxin
What are the symptoms of HUS?
Develop 5-10 days after diarrhea starts
Microangiopathic hemolytic anemia
Thrombocytopenia
Acute renal failure
How is HUS treated?
Antibiotics will WORSEN the condition
Treatment is supportive therapy
What is the etiology of pseudomembranous colitis?
Rare
Overgrowth of C. difficile after or during antibiotic treatment
What are the symptoms of pseudomembranous colitis?
Watery diarrhea
Low grade fever
Leukocytosis
May progress to toxic megacolon and shock
How is pseudomembranous colitis diagnosed and treated?
Diagnosis: Isolation by culture for C. difficle
Treatment: Antibiotics like metronidazole and vancomycin, supportive care
T or F: Rates for C. difficile associated disease in children have been increasing over the last decade.
True
T or F: Asymptomatic carriage of C. difficile is uncommon in infants younger than 1 year
False

It is common
25-33% of asymptomatic 0-36 month patients have stools positive for C. difficile
What are the 4 keys to diagnosing and treating C. difficile associated disease?
Perform testing only on liquid stools
Make sure other etiologies of diarrhea have been ruled out
Dont test infants younger than 1 year of age (unless they have Hirschsprung's)
Don't perform tests for check for cure
What is the cause of appendicitis?
Bacterial infection of the appendix
What are the symptoms of appendicitis?
Pain in lower right quadrant
Abdominal wall rigidity
Migration of pain from umbilicus to lower right quadrant
How is appendicitis diagnosed and treated?
Diagnosis: CT scan
Treatment: surgery, antibiotics if ruptured
What is toxic megacolon and what are some common causes?
Rapid widening of the colon over 1-4 days
Causes:
Infection (shigella)
Pseudomembranous colitis
Hirschsprung disease
IBD
What are the symptoms of toxic megacolon?
Distension
Abdominal pain
Small volume stools with mucous
Tachycardia
Possible shock
How is toxic megacolon diagnosed and treated?
Diagnosed: Physical exam, x-ray, CT
Treatment: decompression, surgery
What is the cause of congenital secretory diarrhea?
Inborn errors of metabolism in which digestion, absorption, transport, etc. are abnormal
What are the symptoms of congenital secretory diarrhea?
Profuse watery diarrhea in the newborn period
How is congenital secretory diarrhea diagnosed and treated?
Diagnosed: Stool studies, genetic studies, newborn screens
Treatment: Condition specific, hydration and nutrition are key
What is the most common cause of diarrhea?
Viruses, specifically norovirus
What are some common extra intestinal causes of diarrhea?
Otitis media
UTI
Pneumonia
What is the difference between acute and chronic diarrhea?
Acute: 5 days or less in duration
Chronic: greater than 1 month in duration
What are three important questions to ask a patient with diarrhea?
Been peeing?
Been able to eat and drink?
Blood in the stool?
What is the gold standard for assessing dehydration?
Weight loss!
T or F: If there is profuse blood in the stool, rule out life threatening conditions such as HUS, intussusception, pseudomembranous colitis, etc.
True
If a child has a fever but non-bloody diarrhea, what is the most likely cause?
Virus

With blood diarrhea, think bacteria
What do you use to rehydrate a dehydrated patient?
Must use isotonic fluid
Normal saline or lactated ringers
When should a person with diarrhea be in the hospital?
Potentially life threatening cause of the diarrhea
Severe dehydration
Lack of improvement with initial therapy
Continued severe diarrhea
Inability or refusal to drink
What are some causes of chronic diarrhea?
Hirschsprung disease
Cystic fibrosis
HIV
IBD
Serial enteric infections
Encopresis