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37 Cards in this Set
- Front
- Back
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Which is larger purpura or petechia?
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purpura
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Does purpura blanch?
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yes
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is a spider angioma a petechiae or purpura?
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purpura
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do spider angiomas blanch?
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yes
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Which is more worrisome, a rash that blanches or doesn't blanch?
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one that does NOT blanch is more worrisome
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what would you think about in your dx/dx if a pt had..
low hgb low neutrophils high wbc's high abnormal lymphocytes low platelets |
leukemia
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in leukemia, what cells are the first to go?
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neutrophils then platelets then rbc's
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leukemia is the failure of ?
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bone marrow proper production of cells
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where is the most common site for a bone marrow aspiration?
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iliac crest
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what fundamental change is taking place int he bone marrow in acute leukemia?
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leukemic cells fail to differentiate, the fail to develp the normal fcn expected of them. they also have a reduced rate of apoptosis (don't die)
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_ is a product of cell metabolism
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urate
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increased protein metabolism will cause a concurrent rise in what biochemical marker?
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creatinine
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with rapid cell turnover what biochemical marker will be elevated?
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lactic dehydrogenase
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the appearance of cells is?
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morphology
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the study of the surface antigens on leukemic cells is__?
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flow cytometry
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myeloid leukemia is found in __
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adults typically over age 50
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what is the usual treatment of leukemia?
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chemo
bone marrow transplant |
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lymphoid leukemia is found in __?
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children
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high platelets, rbc's, hbg, and uric acid levels are indicative of ?
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leukemia
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__ production is a precisely regulated process.
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rbc
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what is polycythemia?
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overproduction of rbc's
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what is the tx of polycythemia?
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phlebotomy
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where does erythropoietin come from?
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mainly in the kidney
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how much blood is removed in phlebotomy for polycythemia?
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1 unit at a time
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what is the target hct in a pt with polycythemia?
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50%
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what problems will your pt have with polycythemia if left untreated?
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problems within the arteries and veins
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a pt. with painless, spontaneous bruising, a low platelet count is indicative of ?
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itp
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is petechiae or purpura common in itp?
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petechiae
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what is petechiae?
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a spontaneous leakage of rbc's into the skin
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a platelet count of <__ could lead to spontaneous bleeding in the body.
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20K
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a platelet count of <__ could lead to a spontaneous intercranial hemorrage.
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10K
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a low platelet count represents that what is happening to them?
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spontaneous destruction of young platelets
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what drugs commonly used in hospitals can cause ITP?
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heparin-HIT
chloramphenical quinine rifampin bactrim |
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what could chloramphenical do the bone marrow?
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suppress it
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what is the tx of ITP?
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watch
IVIG if needed steroids |
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if medical therapy is unsuccessful in the tx of thrombocytopenia and bleeding continues what intervention might be considered?
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splenectomy
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how does removal of the speen compromise the pt?
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increased risk of infection with encapsulated bacteria
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