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52 Cards in this Set

  • Front
  • Back

Spleen Location

Posterior Lt. Hypochondrium


Between fundus of stomach & Diaphram


Spleen is

Largest single mass of lymphoid tissue in the body


Reticulendothelial system (synthesis of blood protein)


Fetal life < 6mo-blood formation (hematopoiesis)


fetal life > 6mo-Defense of Body


Intraperitoneal organ

Spleen Measurements

9-13cm length


~ 7cm AP


3-4 cm thick



generally a little larger than kidney

Blood is supplied to spleen by _____ ______ that travels horizontally along the superior border of the pancreas.

Splenic Artery

_______ is formed by multiple branches within spleen & leaves hilum in a horizontal direction to join the superior mesenteric vein.

Splenic Vein

_______ _______ describes a spleen that has migrated from its normal location in the left upper quadrant.

Wandering Spleen

_______ is complete absence of the spleen.



Splenic Agenesis (a.k.a. asplenic)



Causes no difficulties however may be part of major congenitital abnormality

Accessory Spleen

a.k.a. splenunculus


Common congenital anomaly, failure of fusion


found in 30% of pts.


sono:


homogeneous pattern similar to spleen.


Usually found near the hilum

Spleen is composed of what two components?

White Pulp & Red Pulp

_______ removes old red blood cells through phagocytosis.

Red Pulp

Defense.



_______ consists of small nodular masses of lymphoid tissue attached to smaller arterial branches.

White Pulp

_______ is the process of removing nuclei from red blood cells.

Pitting

_______ is the process of removing or killing off abnormal red blood cells.

Culling

Indicates percentage of RBC's/volume of blood

Hematocrit


(Hct)

Indicates the presence of bacteria in blood.


a.k.a. Sepsis

Bacteremia

An increase in WBC's in the blood that may indicate infection, malignancy, Leukemia or post-op.

Leukocytosis

Abnormal decrease in White Blood corpuscle.



Maybe secondary to bone marrow disorder.

Leukopenia

An abnormal decrease in platelets

Thrombocytopenia

Spleen sonographically

Uniform homogenous mid to low-level echo. More echogenic than that of the liver


Smooth, ovoid, even borders, concave inferior surface

Splenomegaly

Enlargemt > 13cm.


Most common dz. process encountered by sonographer


Volume meas. necessary



s/s:


LUQ pain or fullness

Amyloidosis

Spleen is most freq. involved organ.



sono:


normal ==> enlarged size


Nodular Type: found in walls of sheathed arteries & within follicle but NOT Red Pulp


Diffused Type:Red Pulp Predominantly involved, spleen greatly enlarged & Firm. NO Follicle involvement


Sickle Cell Anemia

Early stage: (infant & child) spleen enlarged w/marked congestion of red pulp


Later Stage: progressive infarction, fibrosis & decrease in size until (Adult) ONLY a sm. mass of fibrous tissue may be found (autospleenectomy)



sono:


spleenomegaly, sudden decrease in Hct., Subacute hemorrhage, hypoechoic in periphery of spleen

Hemolytic Anemia

General term applied to anemia linked to decreased life of erythrocytes.



Rate of destruction > bone marrow compensation



The spleen may be enlarged.

Polycythemia

Excess of RBC's

Polycythemia Vera

Chronic disease of unknown origin


Involves ALL bone marrow elements


s/s:


weakness, fatigue, vertigo, tinnitus, irritability, splenomegaly, flush face, redness & pain in extremities, & blue-&-black spots


sono:


Enlarged, firm, blue-Red, Infarcts & thrombosis

Spleenic Abscess

Uncommon b/c phagocytic activity of spleens efficient reticuloendothelial system & leukocytes.


s/s: subtle


fever, LUQ tenderness, Abd. pain, Lt. shoulder & flank pain, spleenomegaly


sono:


simple cystic pattern ==> mixed echo pattern, lesion may be hypoechoic, may have hyperechoic foci (gas/debris), thick or shaggy walls, anechoic (w/o echoes) poor definition

AIDS

Spleenomegaly most common finding


multi-organ involvement: liver, kidney, spleen


focal lesions


sono:


moderate spleenomegaly, multiple, hypoechoic & well defined sm. round lesions

Splenic infarction

Most common cause of focal splenic lesions Resulting from occlusion of major splenic artery or branches


Almost always result of emboli from heart, mural thrombi or vegatative valve (lt. heart)


sono: localized hypoechoic area,


fresh infarct: hypoechic


healed infarct: echogenic, peripheral, wedge shaped lesion wall


Infarct may become nodular or hyperechoic w/time

Spleen's most commonly injured as a result of _______ _______ _______.

Blunt Abdominal Trauma



splenic hematoma or subcapsular hematoma



sono:


life saving diagnpsis for pts.


i.e. Emergency laporotomy

Splenic cyst's

Parasitic or nonparasitic in origin.


Most secondary cysts by trauma, infection or infarction


sono:


hypoechoic==> anechoic foci w/well defined walls & increased through transmission. sm.==>very lg. Internal echo w/increase Gain.


hemorrhage==>fluid level


Infectious cysts==> calcifications


Post traumatic cysts==>no cellular lining (a.k.a. pseudo cyst) may also have calcification

_______ is the only parasite that forms splenic cysts .


It is uncommon in the US

Echinococcus


is the only parasite that forms cysts

Hamartoma

Asymptomatic.


Solitary or multiple


Considered well defined but not encapsulated


sono:


Both solid & cystic components


hyperechoic

Rare in the pediatric age group

Symptomatic Splenic Hamartomas

Cavernous Hemangioma

Isolated inhomogeneous echogenic mass Multiple sm. hypoehoic areas.


Asymptomatic


Symptomatic only when size of spleen increases & compresses other organs


SONO:


variable, well defined echogenic ==> complex pattern, infarction

Hemangiosarcoma

Rare malignant neoplasm


Arising from vascular endothelium of spleen



sono:


mixed cystic US pattern, resemvles cavernous hemangioma, can be hyperechoic

Lymphoma

Spleen is commonly involved


SONO: difficult to see, When seen typically hypoechoic w/some focal areas, 4 patterns:


1) Diffuse involvement


2) Focal sm. nodular lesion


3) Focal Lg. nodular lesion


4) Bulky dz.


Type1&2 predominantly low-grade Lymphoma & Hodgkin dz.

Metasases

10th most common site


Origin: breast, lung, ovary stomach, colon, kidney, prostate or melanoma


Result of hematogenous spread


microscopic


sono:


Melanoma deposit==>hypoechoic , hyper echo than lymphoma, some echo dense

Gaucher's Dz.

~ 50% < 8 y.o. & 17% < 1 y.o.


s/s: chronmic course w. bone pain & skin PIGEMENTATION



sono:


spleenomegaly, diffused inhomogeneity, multiple nodules (well defined hypoechoic lesions). Irregular hyperechoic or mixed Nodules

Niemann-Pick Dz.

Predominantly Female



s/s:


hepatomegaly, GI disturbances, lymphadenopathy

Diffuse Dz.

Erythropoietic Abnormalities include:


sickle cell,


hereditary spherocytosis,


hemolytic anemia,


polycythemia vera,


thalassemia &


myeloproliferative disorders

Congenital Spherocytosis

Intrinsic abnormality of RBC's



Hereditary or Congenital



Erythrocytes are sm & spherical instead of biconcave disk

Autoimmune HemoLytic Anemia

sono: Spleen variably enlarged



1-without dz.


2-pt. with Lymphoma, Leukemia, Infectious Mononucleosis

Thalassemia

Spleen severly involved.


vary in size & shape



sono:


Spleen very large,


seemingly to fill entire abd. cavity

Myeloproliferative Disorder

include : chronic & acute myelogenous leukemia, polycythemia vera, myelofibrosis, megakaryocyctic leukemia & erythroleukemia


sono:


isoechoic US pattern, parenchyma hypoechoic compared to liver

Granulocytpoietic Abnormalities

include: reactive hyperplasia resulting from acute/chroni infection



sono:


spleenomegaly, diffusely hypoechoic pattern, Bright echogenic lesion with/without shadowing (pt. w/hx. granulo. infect.)


May also have calcium in splenic artery

Reticuloendotheliosis

Hyperactive Reticulendotheia & varying degree of storage of lipids in phagocytes



sono:


isoechoic

Letterer-Siwe Disease

a.k.a. nonlipid reticuloendotheliosis


Proliferation of Reticuloendothelial cells in all tissues


generally < 2 y.o.


s/s: hepatospleenomegaly, fever, Pulm. involvement, Rapidly FATAL


sono:


moderately enlarged

Hand-Schuller-Christain disease

Similar to Letterer-Siwe Dz.


generally >2 y.o.


s/s:


chronic course, DM, hepatospleenomegaly


Lymphopoietic Abnormalities

include: lymphocytic leukemias, lymphoma, Hodgkin dz.



sono:


diffusely hypoechoic spleenic pattern w/ focal lesions


non-Hodgkin lymphoma-isoechoic pattern

Spenic Infection

Most prominent feature-spleenomegaly


sono:


hepatosplenic candidiasis- "Wheel within wheel" pattern w.central hypoechoic area or "Bull's Eye" Pattern, hypoechoic nodule, hyperechoic nodule


Mycobacterial- tiny diuffuse echogenic foci throughout spleen


TB (active)-echo poor cystic masses


Cystic Lympangioma

Benign malformation of Lymphatics


Predominantly somatic soft tissue (neck, retroperitoneum, etc)


Involve Multi-organ system or confined to solitary organ ( liver spleen, kidney, colon)



sono:Appears as a mass w/extensive cystic replacemnt of splenic parenchyma

Splenic Ligaments

Spleenorenal Ligament: (peritoneal ligament) attaches spleen to stomach & Kidney


Gastrosplenic Ligament: separate lesser & greater sac


Lienorenal Ligament:


Phrenicocolic Ligament: