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30 Cards in this Set
- Front
- Back
An exercise for diabetic patients to avoid if they have peripheral neuropathy
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Walking on a treadmill (any repetitive weight-bearing exercise that may cause injury to the feet.)
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These drugs reduce insulin resistance and hepatic glucose production and therefore do not cause hypoglycemia
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Biguanides (Metformin)
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_____, _____, and ____ stimulate insulin release and can cause hypoglycemia
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sulfonylureas, repaglinide, and nateglinide
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2nd generation sulfonylurea that should be used with caution in the elderly - why?
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glyburide - because its metabolites clear more slowly than others'
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oral antidiabetic often used in older adults because of their relative safety
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2nd generation sulfonylureas
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Regular insulin onset, peak, and duration
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onset < 1hr, peak 2-3 hrs, duration 3-6 hrs
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NPH is precipitated with ?
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protamine
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NPH is available in what dosages of premixed NPH/Regular
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70/30 and 50/50
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NPH onset, peak, and duration
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onset 2-4 hrs, peak 4-12 hrs, and duration 10-16 hours
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Type of insulin that must not be diluted or mixed with another insulin or solution and is not for IV use
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Glargine and Lantus (Aventis)
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When should you give rapid acting insulin?
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0-15 minutes before meals
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Names of the rapid acting insulins
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Lispro, Velosulin, Humalog
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Rapid acting onset, peak, and duration
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onset <= 15 min, peak 30-90 min, and duration is 3-4 hrs
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How long after rapid acting insulin has been given would you expect hypoglycemia?
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1-3 hours after injection
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The only insulin that can be given as an IV drip and through an IV undiluted - soluble and rapidly absorbed
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regular insulin
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Intermediate acting insulin
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NPH
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Oral anti-diabetic that decreases insulin resistance but has been associated with elevated liver enzymes
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Thiazolidinediones - liver function monitoring is important
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24 hour, long acting insulin that is given once a day at bedtime
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Lantus (Aventis)
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U100 means there are ___ units of _____ in _____ milliliters of ______.
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100 units of insulin in 1 milliliter of fluid
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Destruction of beta cells in the pancreas; little or no endogenous insulin
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Type I
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Characterized by Polyuria, glucosuria, polydipsia, polyphagia, weight loss, and fatigue
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Type I
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Etiology includes obesity, with diagnosis usually at age > than 30; heredity usually put person at high risk
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Type II
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Compensatory mechanism to get rid of CO2 (acid) in DKA
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Kussmaul's respirations
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Major manifestaton of DKA
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Dehydration (hyperglycemia >300mg)
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Pathophysiological factors include genetic predisposition, viral or toxic chemical agents, and autoimmune attack
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Type I
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How long can regular insulin be stored unrefrigerated?
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Up to 30 days
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How long can mixed insulin be stored unrefrigerated?
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14 days or <
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Important storage fact to remember for insulin
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Keep out of sunlight
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How/when should Metformin (Glucophage) be given?
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Give with meals - do not give if there is a decrease in kidney function
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Most common cause of sudden death in diabetes
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cardiac problems
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