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23 Cards in this Set
- Front
- Back
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Generic name of Byetta |
exenatide |
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Generic name of bydureon
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exenatide ER
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Generic name of victoza
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liraglutide |
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Trade name of lispro
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Humalog
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Trade name of glargine
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Lantus
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Trade name of detemir
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levamir
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Precautions when starting GPL-1
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reduced dose of insulin |
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Advantages of sulfonylureas
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low-cost, oral drug,
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Disadvantages of sulfonylureas
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potential for hypoglycemia, weight gain, cardiovascular safety |
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Advantages of SGL-2 inhibitors
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weight loss, lower systolic blood pressure, oral drug |
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Disadvantages of SGL 2 inhibitors
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genital mycotic infections, hypotension, cost |
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Advantages of TZD
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durability, variable cost |
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Disadvantages of TZD drugs
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edema, CHF, weight gain, fractures |
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Advantages of DPT 4 inhibitors
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weight neutral, oral drug |
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Disadvantages of DPT 4 inhibitors
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possible congestive heart failure, cost, possible pancreatitis |
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Advantages at GLP-1
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weight loss, reduced blood pressure |
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Disadvantages of GLP-one inhibitors
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GI fracture, pancreatitis, cost, injectable drug |
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Disadvantages of insulin
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hypoglycemia, weight gain, injectable drug |
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Effects of GPL 1
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glucose dependent insulin secretion, blunts glucagon effect, reduces gastric emptying, weight loss, improves CV risk |
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Rank diabetic drugs by efficacy |
biphasic insulin, GLP-1 basal insulin TZD glinides DPP 4 AGI |
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Effects of DPP-4 inhibitor |
increases postprandial GLP-1 and GIP, increase his insulin secretion decrease his glucagon secretion |
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What the available DPP-4 drugs |
stagliptin saxagliptin linagliptin alogliptin |
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Define DPP 4
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Dipeptidyl peptidase-4 inhibitor
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