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17 Cards in this Set

  • Front
  • Back
Pancreatic
Influenced by glucose levels
Secreted by the Islets of Langerhans
Insulin ( b cells)
Amylin ( b cells)
Glucagon (a cells)
Pancreatic
Influenced by glucose levels
Secreted by the Islets of Langerhans
Insulin ( b cells)
Amylin ( b cells)
Glucagon (a cells)
Gastrointestinal (Incretins)
GLP-1 (glucagon-like peptide 1)
GIP (glucose-dependent insulinotropic peptide)
Gastrointestinal (Incretins)
GLP-1 (glucagon-like peptide 1)
GIP (glucose-dependent insulinotropic peptide)
*Normal fasting blood glucose ?
70-110
*Normal fasting blood glucose ?
70-110
Glucose > 110 mg/dL
stimulates insulin secretion
prevents hyperglycemia
Glucose > 110 mg/dL
stimulates insulin secretion
prevents hyperglycemia
Glucose < 70 mg/dL
stimulates glucagon secretion
prevents hypoglycemia
Glucose < 70 mg/dL
stimulates glucagon secretion
prevents hypoglycemia
Insulin
allows glucose to enter cells
allows glucose to enter liver
inhibits release of liver glycogen
inhibits fat breakdown
Amylin
slows gastric emptying
promotes satiety
inhibits secretion of glucagon (decreases hepatic glucose output)
reduces total insulin
demand
Glucagon
responds to
hypoglycemia & stress
promotes glucose
production in liver &
raises blood glucose
inhibited post meals
excessive in insulin deficiency
Incretins (GIP, GLP-1)
stimulates insulin release
reduces glucagon
production
delays gastric emptying
improves insulin
sensitivity
may increase # of new
pancreatic beta cells
Glycogenolysis
makes glucose from protein & fat
Gluconeogenesis
shuts down after meal
stores energy
Avaliable units of insulin
U-40 units per mL (not in U.S.)
U-100 100 units per mL
U-500 500 units per mL