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6 Cards in this Set

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  • Back
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Biguinide

Met firm in, first line


Insulin sensitized


GI upset


Lactic acidosis


Stop using if GFR <30, liver, renal, alcoholic disease

Big and wide

TZD

Pioglitizone (actos)


Insulin sensitize


Check LFTs before during, water retention, edema


Do not use in HF 3and 4, liver disease, pregnancy


Decrease lipids and risk of MI

Glitizone-no HF zone

Sulfonylures

Glipizide (glucotrol)


Constant insulin release


Good for BG >300/A1C >9.5


Not good for older adults


Increased risk of CV mortality


Renault excreted, no kidney or liver disease

Sugar “ide” hate to drop


Sulfa allergy

DPP-4 inhibitors

Sitagliptin (januvia)


Insulin release post glucose rise


Caution with heart failure


May be renal protective and decrease albuminuria


Joint pain, angioedema, acute pancreatitis

Fall 4 duck lips (Lipton’s)

GLP-1 agonist


Injection

Exenatide (byetta), liraglutide (victoza)


Insulin release post glucose rise


Avoid in GI disease, pancreatitis CR clearance <30, family hx med thyroid CA, endocrine neoplasia


Slows stomach empty, reduces cardiac events, lose weight

SGLT2 inhibitors

Renal glucose excretion post glucose rise


Canagliflozin (invokana), empagliflozin (jardiance)


Don’t use GFR <30-45, UTI, candidiasis, bone fx, AKI, DKA


Decrease of CV events, renal protective, slows CKD, decrease BP

Flozin