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24 Cards in this Set
- Front
- Back
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sulfonylureas examples
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glipizide (glucotrol)
gluyburide (micronase, diabeta) glimerperide (amaryl) |
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sulfonylureas actions
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simulate release of insulin from pancreatic islets
decrease glycogenosis/glucogenosis enhance cellular sensitivity to insulin |
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meglitinides
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repaglinide (Prandin)
nateglinide (starlix) |
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meglitinides action
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stimulate rapid and short lives release of insulin from pancrease
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biguanide
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metformin (glucophage, fortamet)
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biguanide action
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decrease rate of hepatic glucose production
augment glucose uptake by tissues, especially muscles |
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alpha glucosidase inhibitors
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acarbose (Precose)
miglitol (Glyset) |
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alpha glucosidase inhibitors action
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delay absorption of glucose from GI tract
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thiazolidienediones
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pioglitazone (actos)
rosiglitazone (avandia) |
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thiazolidienediones action
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increase glucose uptake in muscle, decrease endogenous glucose production
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dipeptidyl-peptidase-4 (DDP-4) inhibitors
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sitagliptin (Januvia)
saxagliptin (onglyza) |
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DDP-4 inhibitor action
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enhance serum incretin
stimulates release of insulin from pancreatic b cells decrease hepatic glucose production |
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incretin mimetic
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exenatide (byetta)
liraglutide (victoza) |
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incretin mimetic action
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stimulates release of insulin
decrease glucagon secretion increase satiety decrease gastric emptying |
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amylin analog
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pramlintide (symlin)
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amylin analog action
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decrease gastric emptying
decrease glucagon secretion decrease endogenous glucose output from the liver increase satiety |
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rapid acting insulin
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lispro (humalog)
aspart (novolog) glulisine (apidra) |
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rapid acting insulin action
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onset - 15 minutes
peak - 60-90 minutes duration - 3-4 hours |
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short acting
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regular (humulin R, novolin R, reliON R)
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short acting insulin action
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onset 1/2 to 1 hr
peak 2-3 hours duration 3-6 hours |
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intermediate acting
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NPH (Humulin N, novolin N, ReliOn N)
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intermediate acting action
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onset 2-4 hours
peak 4-10 hours duration 10-16 hours |
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long acting
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glargine (lantus)
detemir (Levemir) |
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long acting action
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onset 1-2 hours
peak - no pronounced peak duration 24+ hours |
