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15 Cards in this Set

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Rapid Acting Insulin
Humalog, Novalog, Apidra, Lispro
Onset 15 min 0-15 before meal
Short Acting Insulin
Regular
onset 30-60 min 30-45 before meal
Long Acting Insulin
Lantus, Levemir
steady & continuous no peak
Intermediate Acting Insulin
NPH
peak 4-10 hours
What is the Somogyi Effect?
Rebound effect where an overdose of insulin induces hypoglycemia (usually during sleep) - tx less insulin
What is the Dawn Phenomenon?
hyperglycemia that is present upon waking in the morning due to the release of counterregulatory hormones in the predawn hour- tx adjustment in the timing of insulin admin. or increase in insulin
Name some Sulfonylureas & their primary action.
Glucotrol, Micronase, Diabeta, Glynase, Amaryl, Diabinese
increase insulin production from pancreas- may cause hypoglycemia
Name some Meglitinides & primary action.
Prandin, Starlix- increase insulin production from pancreas, less likely to cause hypoglycemia- 0-30 min before meal
Name some Biguanides & primary action.
Glucophage (Metformin), Glucovance, Avandamet, Metaglip, Janumet- decrease glucose prod. by liver, also used in prev. of diabetes
Name some A-Glucosidase Inhibitors & primary action
Precose, Glyset- "starch blockers" slow down absorption of carbs in small intestine- take with 1st bite of each meal
Name some Thiazolidinediones & primary action.
Actos, Avandia- insulin sensitizers, improves insulin sensitivity, transport, & utilization @ target tissues
Name some DPP-4 Inhibitors & primary action.
Januvia, Onglyza, Galvus, inhibit DPP-4 slowing the inactiviation of incretin hormones, glucose dependent absence of weigh gain, cause stomach to empty slowly, metabolize drugs slowly
Name some Incretin Mimetics & primary action.
Byetta, Victoza- simulates one of the incretin hormones, stimulates insulin from pancreas, before bf or dinner to avoid hypoglycemia
Names an Amylin Analog and primary action.
Symlin- slows food emptying from the stomach and curbs appetite, administered subq can cause sever hypoglycemia
What to beta blockers do?
mask symptoms of hypoglycemia, prolongs effects of insulin