Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
34 Cards in this Set
- Front
- Back
|
what do Sulfonylureas do
|
stimulate Beta cells in the pancreas to secrete insulin and are also K channel blockers
|
|
|
what are all the 1st gen Sulfonylureas
|
tolbutamide, acetohexamide, tolazamide, chlorpropamide
|
|
|
tolbutamide
|
1st gen sulfonylurea
|
|
|
acetohexamide
|
1st gen sulfonylurea
|
|
|
tolazamide
|
1st gen sulfonylurea
|
|
|
chlorpropamide
|
1st gen sulfonylurea
|
|
|
glipizide
|
2nd gen sulfonylurea
|
|
|
glyburide
|
2nd gen sulfonylurea
|
|
|
glimepiride
|
2nd gen sulfonylurea
|
|
|
what is the generic name for Glipizide
|
glucotrol
|
|
|
what is the generic name for glyburide
|
diabeta, glynase, micronase
|
|
|
what is the generic name for glimepiride
|
amaryl
|
|
|
what are the 2nd gen sulfonylureas
|
glipizide, glyburide, glimepiride
|
|
|
what are the insulin secretagogues
|
sulfonylureas and repaglinide, nateglinide
|
|
|
what is the generic name for nateglinide
|
starlix
|
|
|
what do Biguanides do
|
increase insulin binding to insulin Rc
|
|
|
Metformin
|
Biguanide
|
|
|
what is the generic name for Metformin
|
glucophage
|
|
|
what do Thiazolidinediones (TZD) do
|
selective PPAR gamma receptor agonist therefore regulating transcription of insulin responsive gene involved in glucose transport etc
INSULIN SENSITIZER |
|
|
troglitazone
|
TZD
|
|
|
pioglitazone
|
TZD
|
|
|
rosiglitazone
|
TZD
|
|
|
what is the generic name of troglitazone
|
resulin
|
|
|
what is the generic name of pioglitazone
|
actos
|
|
|
what is the generic name of rosiglitazone
|
avandia
|
|
|
Acrabose
|
oligosaccharide
|
|
|
what is the generic name of Acrabose
|
Precose
|
|
|
what are some of the properties of Acrabose
|
water soluble
side effect : causes a lot of gas |
|
|
what is the therapeutic effect of Acarbose
|
inhibits alpha amylase and membrane bound alpha glucosidase thereby stopping the break down of carbohydrates into glucose
|
|
|
Miglitol
|
alpha glucosidase inhibitor
|
|
|
what is the therapeutic effect of Miglitol
|
alpha glucosidase inhibitor stopping the breakdown of carbs into glucose
|
|
|
what is the generic name of Miglitol
|
Glyset
|
|
|
how many metabolites does glyburide, glipizide, and glimepiride have
|
glyburide/glipizide has two metabolites both of which are inactive
glimepiride has 2 actives one of which is active |
|
|
are sulfonlyureas acidic or basic
|
acidic
|
