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10 Cards in this Set

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Sulfisoxasol
Available alone or with erythromycin (a macrolide) in generic form for kids with recurrent otitis media
sulfamethoxazole: available with what other drug?
available with trimethoprim aka co-trimoxizole TMP-SMZ
sulfacetamide
bleph-10, Topical treatment used on eyelid for ulcerative blepharitis. S. Aureus and S. Epidermidis usually cause
Silver Sulfadiazine
Used to treat burns to prevent sepsis. sulfa can be absorbed if covering a large area.
Mafadine
used for burns. Can cause metabolic acidosis by inhibiting carbonic anhydrase.
CRYSTALLURIA
Side effect of sulfa drugs. recommended drinking lots of water
KERNICTERUS billirubin encephalopathy
Sulfa drugs displace billiruben from serum albumin and enter CNS.
When should sulfonimides be avoided?
Last months of pregnancy and in infants less than 2 months old.
Blood Dyscrasias
Rare sida effect of sulfonamides. acute hemolytic anemia, agranulocytosis, aplastic anemia. Rare but can be FATAL. Do not use topicals if there is a known Hx of blood dyscrasias.
What is Stevens-Johnson syndrome?
Hypersensitivity Rxn from sulfonamides. fever, headache, cough & conjunctivitis followed by macules on face, neck & other areas eventually forming bullous eruptions on skin & mucous membranes.