Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
15 Cards in this Set
- Front
- Back
|
neural plate folds in and fuses at teh dorsal lip to form? |
neural tube |
|
|
NEP soma moves along have a small process attached to the basal and apical surface of the ventricular zone known as the |
interkinetic nuclear migration |
|
|
asymmetric inheritance of ______ and _____ is necessary for maintaining neural progenitor state |
NOTCH, PAR3 |
|
|
morphogens______ and ______ establish neural progenitor domains in the neuroepithelium |
SHH, BMPS |
|
|
(how does a tube turn into a brain?) Multiple morphogens generate complez patterns of transcription factor expression.. which morphogens? |
FGF8 (rostral forebrain), BMPs/WNTs (caudal cortex), Shh (ventral forebrain) |
|
|
to make a cortex you need what kind of cell |
Radial Glia ( NEP generated) |
|
|
early born neurons populate layer___ Later born neurons populate layer ___,___ |
6, 2/3 |
|
|
How is the human cortex folded (gyrencephalic) |
Suci (valleys) gyri (ridges) allows for more complex circuit architecture and processing power |
|
|
following a period of neurogenesis, radial glia transition into a______ mode to produce glia which are _________,_________and________ |
Gliogenic. , (astrocytes, oligodendrocytes, and ependymal cells) |
|
|
oligodendrocytes develop postnatally and _______ to form white matter |
myelinate |
|
|
what is the blood brain barrier BBB |
physically separate blood from neurons tight junctions fill gap between endothelial cells. regulates transport of cellular, subcellular, and ionic components into brain |
|
|
Astrocytes regulate |
Ion homeostasis, metabolic support, blood brain barrier, synaptic transmission |
|
|
cerebrospinal fluid (CSF) is generated by the ______ ______ |
choroid plexus |
|
|
radial glia generate _______ cells that line the ventricular surfaces of the brain |
ependymal |
|
|
blockage of CSF (cerebral spinal fluid) flow through the ventricles causes? |
Hydrocephalus: can lead to severe neurological defects |
