Development Of The Urinary System

Front 1

What does the urinary system composed of?

Back 1

1. Kidneys
2. Ureters
3. Urinary bladder
4. Urethra

Front 2

Where does the urinary system develop from?

Back 2

The urogenital ridge of the intermediate mesoderm

Front 3

Name the three sets of kidneys

Back 3

1. pronephros
2. mesonephros
3. metanephros

Front 4

When does the the pronephros begin to develop?

Back 4

4th week

Front 5

At what level does the pronephros develop

Back 5

The cervical level, specifically C5-C7

Front 6

Whats another name for the mesonephric duct?

Back 6

Wolffian duct

Front 7

Which direction does the mesonephric duct grow? And with with which structure does it fuse with

Back 7

It grows caudally and fuses with the cloaca

Front 8

What empty into the mesonephric duct ?

Back 8

Lots of mesonephric tubules

Front 9

What three structures appear to fuse or become connect with the cloaca?

Back 9

1. mesonephric duct
2. alantois
3. hindgut

Front 10

From what? and how is the urogentital ridge formed?

Back 10

Formed from bulging of intermediate mesoderm into coelomic cavity

Front 11

How does the mesoneprhic duct form

Back 11

Its forms as a condensation of intermediate mesoderm

Front 12

What does the urogenital ridge of the intermediate mesoderm differentiate into?

Back 12

It differentiates into
1. Medial genital ridge (with germinal epithelium)
2. Lateral nephrogenic ridge

Front 13

How does the paramesonephric duct form?

Back 13

It forms as an invagination of visceral peritoneum ( of the Lateral nephrogenic ridge? I think)

Front 14

The mesenephros extends from the the upper thoracic to L?

Back 14

L3

Front 15

______ ducts induce Intermediate Mesoderm to form vesicles

Back 15

Mesonephric

Front 16

Upon forming mesonephric vessicles, what happens?

Back 16

Tubules form beween the vessicles and the duct (which gives rise to bowmans capsule).

Front 17

When do the tubules of the mesonephric duct become functional

Back 17

Around the 6th - 10th week

Front 18

What happens to the tubules of the mesonephric duct

Back 18

The degenerate at the end of the 1st trimester. The tubules(?) remain in males and become efferent ductules of the testes

Front 19

When does the metanephros develop

Back 19

5th week

Front 20

What are the two functional components of the metanephros

Back 20

1. Excretory system (Metanephric mesoderm)
2. Collecting system

Front 21

Name four parts of the excretory system?

Back 21

1. Bowmans capsule
2. Proximal Convoluted tubule
3. Loop of henle
4. Distal convoluted tubule

Front 22

Name four parts of the collection system?

Back 22

1. renal pelvis
2. major & minor calyces
3. collecting tubules
4. ureter

Front 23

The metanephric diverticulum (ureteric bud) branches off of whart?

Back 23

Mesonephric duct

Front 24

The stalk of the metanephric diverticulum becomes what later?

Back 24

Ureter

Front 25

When does the metanephros develop and become functional

Back 25

begins to develop at 5th week and functional at the 9th week.

Front 26

The end of each _____ _____ induces mesenchyme to become metanephric blastema via FGF2 and BMP7

Back 26

collecting tubule ( originated from ureteric bud)

Front 27

What elongates and forms bowman's capsule, PCT, loop of Henle, and DCT?

Back 27

Nephric vesicle (which came from the metanephric blastemal cap)

Front 28

Name the two types of Congenital Polycystic kidney Disease?

Back 28

1. Autosomal recessive
2. Autosomal dominant

Front 29

This type of Congential polycystic kidney disease is describes as

1. Renals fails soon after birth or early during childhood
2. The collecting tubules have cysts
3. The liver may often have cysts also

Back 29

Autosomal recessive

Front 30

This type of congenital kidney disease is describes as
1. Renal failure during your 40's or 50's
2. Cysts all over the nephron
3. It is often accompanies with
------1. liver cysts, 2. intracranial berry aneurisms, 3. mitral valve prolapse

Back 30

Autosmal dominant

Front 31

How is the kidney positioned

Back 31

Originally in the neck (pronephros) then from the pelvis, it ascends cranialy

Front 32

What do you call a kidney that fails to ascend?

Back 32

Pelvic kidney

Front 33

What happens if you have horseshoe kidney? Effects

Back 33

The metanephric mesoderm fused together. As it ascend it gets trapped by the inferior mesenteric artery off of the aorta and stops at the position of the pelvic brim.

Front 34

_______ is the most common primary renal tumor of childhood, and 4th most common pediatric malignancy in the U.S.
-usally diagnosed before age 5
-Maybe associated with other abnormalities and syndromes

Back 34

Wilms tumor

Front 35

What happens with Renal agenesis

Back 35

Kidneys do not develop. If bilateral, the fetus will die and is often associated with other disorders. Fetus exhibits anuria (can't urinate) which results in lack of amniotic fluid (oligohydramnios.

Front 36

What artery feeds the kidneys

Back 36

Renal artery

Front 37

How are the kidneys supplied blood as they rise

Back 37

New renal arteries attach and lower ones unattach

Front 38

What sits on the kidneys or closely to it?

Back 38

Suprarenal gland

Front 39

What happens during the 4th - 7th week?

Back 39

The cloaca is divided into urogenital sinus and anal canal

Front 40

What divides the cloaca into urogenital sinus and anal canal

Back 40

urorectal septum

Front 41

The urogenital sinus is made up of three parts?

Back 41

1. cranial (urinary bladder)
2. pelvic (urethra in bladder neck)
3. caudal )

Front 42

What does the cranial part of the uregenital sinus become

Back 42

It becomes the urinary bladder, which is continuous with the alantois which later degenerates to a fibrous chord called the URACHUS, which forms the MEDIAN UMBILICAL LIGAMENT

Front 43

What does the pelvic portion of the urogenital sinus become

Back 43

It becomes the urethra in the bladder neck, prostatic urethra in males and entire urethra in females

Front 44

What does the caudal part of the urogenital sinus become?

Back 44

Genital tubercle? (No idea?) and penile urethra in males.

Front 45

What makes up the trigone?

Back 45

The bladder and a pair of mesonephric ducts (with ureteric bud)originally. But later is made up of posterior wall of bladder, mesonephric duct pair, and a pair of ureters. ( originated from ureteric bud).

Front 46

What is persistant intraembryonic allantois?

Back 46

1. urachal fistula
2. urachal cyst
3 urachal sinus

Front 47

What type of defect is exstrophy of the bladder?

Back 47

Ventral body wall defect, where bladder mucosa is exposed