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5 Cards in this Set

  • Front
  • Back

FA/FI curve points

Reaches 0.5 within a minute


plateaus between 10-15 minutes at 0.9




Rate of rise:


N20>Des>Sevo>iso>En>Halo

FA/FAO

At 0.2 by about 4 mins


At 0.1 by about 7 minutes


just above 0.01 at 120mins




Rate of decrement


N20>Des>Sevo>iso>En>Halo

Context sensitive decrement times

50% and 80% decrement times remain the same (2 and 5mins) with different durations of anaesthetics


90% decrement time - increases with increasing duration of anaesthetic but minimally (ie 10mins at 350mins)

Metabolism

0.02%


Liver- oxidative P4502E1

Toxic Metabolites

⇒HF + unstable product ⇒2 inorganic fluoride + Trifluoracetic acid (CO2 + water)




results in no toxicity