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25 Cards in this Set
- Front
- Back
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What are lesions associated with Pemphigus vulgaris
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Vesiculobullous (erosive to ulcerative)
oral cavity mucocutaneous junction and or skin clawbeds +systemic illness signs |
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How do you diagnose Pemphigus vulgaris
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Histopath
suprabasilar acantholysis cleft and vesicle formation |
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How do you treat Pemphigus vulgaris
what is outcome |
Glucorticoid
Azathioprine chlorambucil Guarded |
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What are lesions associated with paraneoplastic pemphigus
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flaccid vesicles, erosions and ulcers
on mucosa, MC junction and haired skin |
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What are lesions associated with pemphigus vegetans
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extremely rare!
PV like mucosal erosions hyperplastic warty skin lesions |
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What lesions are associated with pemphigus erythematosus
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Erythematous pustular dermatitis on face, nose and ears
nasal depigmentation |
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How do you diagnose pemphigus erythematosus
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-history
-PE -cytology -Database to rule out other causes -Histopath |
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How do you treat pemphigus erythematosus
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-avoid exposure to sunlight
-topical sunscreen -Topical tacrolimus -topical steroid -Doxy + niacinamide |
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What is 2nd most common immune mediated dermatitis
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Discoid lupus erythematosus
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What are early lesions associated with discoid lupus erythematosus in dogs
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Dipgmentation
scaling of nose erythema of nose loss of cobblestone appearance |
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What are late lesions associated with discoid lupus erythematosus in dogs
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ulceration
erosion crusting spreading up bridge of nose periocular / pinna / distal limb / genitals/ oral cavity |
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What are lesions associated with discoid lupus erythematosus in cats
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lesions on face and pinna
erythema scale crust alopecia |
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What is main R/o with suspected DLE
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mucocutaneous pyoderma
=same clinical presentation and histopath |
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How do you treat DLE
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same as for PE
sunscreen tacrolimus topical steroid doxy/niacinamide |
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What is pathophysiology of systemic lupus erythematosus
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genetic predilection
T cell deficiency B cell hyperactivity and auto ab form against body constituents Type III hypersensitivity cause tissue damage |
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What are CS of systemic lupus erythematosus in dog
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Fever
polyarthritis proteinuria skin manifestations > 50% cases +/- pruritis |
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How do you diagnose SLE
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clinical presentation
anti-nuclear ab (not definitive) Histopath |
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What is treatment and prognosis for SLE
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Glucocorticoids
Azothiaprine / Chlorambucil Guarded prognosis |
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What is mechanism for vasculitits
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Type III hypersensitivity
coexisting disease precipitating factor - infection, drug, vaccine Idiopathic (50%) |
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Where is vasculitis most common
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areas of pressure and extremities
pinnae tip of tail paw scrotum oral mucosa |
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What are CS of vaccine reaction vasculitits
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alopecia and induration of injection site
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How do you treat Vasculitits
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treat underlying cause (ie Vx - then minimize for future)
Pentoxifylline Immunosuppresion |
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what are disease characteristics of canine juvenile cellulitis
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Granulomatous and psutular disorder of face and pinna - lesions will fistulate, drain and crust
submandibular lymphadenopathy juvenile dog: 3 weeks - 8 mos |
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How do you diagnose canine juvenile cellulitis
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Derm database to R/o other causes
Cytology: pyogranulomatous inflammation with no m/o Histopath: Granuloma, the glands obliterated |
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How do you treat canine juvenile cellulitis
what is prognosis |
Systemic ab
Glucocorticoid at immune suppressive doses Excellent |
