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27 Cards in this Set
- Front
- Back
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Seborrheic Keratosis
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-Verrucous surface/warty, commonly darkly pigmented, stuck on appearance. -Onset in 30s, unknown cause -Rx=observation, liquid Nitrogen, surgery, laser. Called Dermatosis Papulosa Nigra when many dark ones on darker skinned ppl think Morgan Freedman *Sign of Leser-Trelat(paraneoplastic sign)=explosive onset of itchy seborrheic keratosis in older adult and usu. sign of adenocarcinoma of stomach.
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Achrochordons "skin tags"
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papilomatous, pedunculated "bag like tumor attached by stalk" lesions that are flesh colored. Located on friction areas( neck, axilla, groin, inframammary) Middle age onset. assoc w/ SK maybe also colonic polyps.Rx=snip or cryotherapy
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Dermatofibroma
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Brown, firm nodules located on extremities. See dimple sign on compression wo>men. May be exaggerated response to injury.
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Neurofibroma
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Soft, flesh colored papule may be solitary or multiple. Rx=excision Neurofibromatosis (Von Recklinghausen's Dz) has cafe au lait spots and internal NF
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Lipoma
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Fatty tumor, single or multiple soft round mobile, non-tender, subQ tumor Grows Slowly Rx=excision. DDx includes epidermal inclusion cyst
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Epidermal Inclusion Cyst
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Cyst derived from epidermal part of hair follicle. filled w/ keratin and lipid debris. M>wo. Can see opening of hair follicle. Caused by acne, trauma. Can get infected if ruptures. In DDx w/ Lipoma. Gardner's Syndrome-multiple EICs and osteoma, fibroma, lipoma, leiomyomas, colorectal polyps.
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Pilar Cyst
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from hair on scalp. Similar to epidermal inclusion cyst but from different part of hair follicle.
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Keloid
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Fibroblastic response to injury includes hyperplastic scar that extends beyond site of injury. More common in dark skinned ppl. Found on sternum, neck, ears, back legs. Rx= intralesional steroids, cryotherapy
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Becker's Nevus
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Non-melanocytic nevus. hairy brown patch around shoulder. M>W. thickens and grows hair at puberty. Excise.
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Ephiledes (Freckles)
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light brown macules, familial, cheeks, Fade in winter. Rx= sun protection
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Solar Lentigo
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Localized melanocytic prolif. "Liver spots" from chronic life time exposure to sun. Darker than freckles and dont fade as much in the winter. *Peutz-Jeghers Syndrome is AutoDom., lentigines on lips, oral mucosa and backs of hands and feet. Presents w/ abd pain, intenstinal polyposis. Rarely converts to adenocarcinoma.
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Nevus
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Developmental Defect
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Melanocytic Nevus
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* can transfer into melanoma like Mole, Junctional nevus, intradermal nevus,cmpd nevus, nevus spilus, blue nevus, congenital nevus, halo nevus, dysplastic nevus
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Non-melanocytic Nevus
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for example like Becker's nevus (hairy patch on shoulder), epidermal nevus, basal cell nevus, nevi comidonicus
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Junctional Nevus
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Melanocytes at dermis-epidermal junc. Macules of varying brown color, round oval smooth borders Diappear >60 years
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intradermal Nevus
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melanocytes in Dermis only. Papules of varying light color, round dome shaped w/ smooth borders, appear in 20s or 30s and dont diappear ever. Have Hair. Not malignant.
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Cmpd Nevus
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melanocytes in both dermis and Epidermis-Dermis junc. papules of varying brown color round dome shaped w/ smooth borders elevated. appear in 20s or 30s and dont diappear ever.
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Nevus Spilus
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Speckled patch usu. acquired in childhood. Rarely turns to melanoma.
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Blue Nevus
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Small well circumscribed blue nodule. Melanocytes very deep in dermis. May be Malignan variant
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Congenital Nevus
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Flat at birth , thickened w/ age. PREMALIGNANT
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Halo Nevus
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hypopigmented halo around pigmented papule or macule. Immune system attacks melanocytes surrounding mole. Associated w/ vitiligo (over reacting immune sys) and metastatic melanoma (immune system trying to kill melanoma). Benign in kids. suspicious in adults.
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Dysplastic nevi
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Large w/ irregular pigmentation and border. Increased RISK OF MELANOMA if multiple or if +family Hx
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Basal Cell Carcinoma
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Course: slow growing and dbles in size every 5 hrs. see in old ppl, rarely metastasize but locally destructive. Cause: UV radiation, arsenic exposure, genetic cond, radiation. Subtypes: Nodulo-ulcerative (pearly translucent shiny flesh colored papule w/ telangiectaisa and have cntral ulceration or rodent ulcer) Superficial (red scaly macules or plaques may look like eczema, tinea, actinic keratosis) Morpheaform/Infiltrative (scar-like plaques that grow) Pigmented (colorful variant of nodular subtype confused w/ Sk or Melanoma. Gooy look)<=ON TEST pigmented BCC. Rx=radiation, electrodesiccation, topical chemo, excision
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Actinic Keratosis
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Red scaly macules on sun damaged skin w/ "sand paper" feel. PRECURSOR to SCC
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Squamous Cell Carcinoma
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older pts, thicker than actinic keratosis and not BCC b/c not shiny or gooey. sun exposed skin. ulcerative or hyperkeratotic papules/nodules/tumors at high risk for METASTASIS. Risks=UV light, arsenic exposure, ionizing radiation, tars and oils, chronic inflammation, immunosuppresssion. Rx=radiation, lymph node dissection, chemo maybe otherwise treat as BCC.
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Bowen's Dz.
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"SCC in Situ" looks like superficial BCC and eczema. Red Scaly plaque usually solitary but may be multiple. Less aggressive and have INCREASED incidence of INTERNAL MALIGNANCY
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Malignant Melanoma
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incidence increasing faster than any other CA. Asymmetry Border irregularity Color variegated Diameter Evolution Family hx (ABCDEF) Earliest sign= Pruritus, tendernes, bleeding, ulceration. Risk=UV light, many nevi or congenital nevi, dysplastic nevus syndrome, family Hx. Types: Superficial spreading (flat), nodular, acral Lentiginous, Lentigo Maligna (in sun exposed areas large irregular and out of solar lentigo esp. in face). Prognosis based on BRESLOWs thickness, ulceration, location. Tx= wide local excision, sentinal node biopsy in which you inject dye and see which node it goes to and take it out, immunotherapy
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