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27 Cards in this Set
- Front
- Back
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What are the main types of psoriasis?
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Vulgaris (most common), Guttate, and Generalized Acute Pustular (Von Zumbusch)
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Psoriasis vulgaris - main feature?
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chronic scaling papules/plaques, silvery white
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Psoriasis vulgaris - etiology?
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related to minor trauma or genetics Type I = Early onset, females
Type II= late onset, males Genetics = HLA B-13, B-17,Bw57, CW6 Trigger Factors= Koebner's phenomenon, Streptococcal infection, drugs |
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Psoriasis Vulgaris - history (onset, skin, constitutional problems)?
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months or sudden onset (acute guttate & von Zumbusch)
skin: pruritus, esp in scalp and anogenital constituional symptoms: psoriatic arthritis & VZ acute illness syndrome |
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psoriasis vulgaris- phys exam findings?
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silvery white papules/plaques, AUSPITZ phenomenon, salmon color/round shape
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psoriasis vulgaris- treatment?
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avoid scratching (increases koebner's phenomenon); Topical agents, UV/ methotrexate
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Guttate psoriasis- main findings?
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Exanthem (shower of lesions)
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guttate psoriasis- pathology?
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possibly due to Streptococcal Pharyngitis
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guttate psoriasis- physcial exam findings?
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guttate (drop-like), scattered lesions of 2mm-1cm, salmon color, ATTACKS THE TRUNK (spares palms and soles)
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guttate psoriasis- treatment?
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UVB, phototherapy, penicillin, erythromycin......guttate sometimes self-limited
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Scalp type psoriasis vulgaris- history?
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Koebnar's phenomenon in the scalp (can't be treated with phototherapy!)
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scalp type psoriasis vulgaris- physical exam findings?
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scattered thick plaques, lichenification, exudation and fissuring behind ears
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scalp type psoriasis vulgaris- treatment?
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tar/ketoconazole shampoos, Vit D3 analogues, aspirin, mineral oil, floucinoine
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Nail type psoriasis vulgaris- physical exam findings?
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-concomitant arthritis
-pitting hyperkeratosis -Onycholysis -Oil spots (yellow/brown) |
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Nail type psoriasis vulgaris- treatment?
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-PUVA
-methotrexate -Intradermal triamcinolone acetonide |
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Palm/Sole type psoriasis vulgaris- treatment?
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-combinations of PUVA and Retinoids
-topical corticosteroids & UVB - USELESS |
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Palmoplantar Pustulosis- definition?
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"Numerous sterile, yellow, deep-seated pustules that evolve into dusky-red macules"
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Palmoplantar Pustulosis- physical exam findings?
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2-5mm pustules, macules; Attacks thenars & flexors, spares acral portions
-Chronic & Remittant |
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palmopustular pustulosis- treatment?
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PUVA
Etretinate |
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Acute Pustular Psoriasis (von Zumbusch) ["VZ"] -- General definition/description?
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abrupt onset of burning erythema that spreads w/in hours to large areas of fiery-red skin; appearance of pustules in clusters which become 'lakes' of purulent fluid
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VZ- physical exam findings?
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lakes of pus
attacks flexural/anogenital regions onycholysis hair loss HA/chills/fever/malaise overwhelming bateremia is NEGATIVE |
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VZ- treatment?
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hospitilization
Retinoids PUV photochemotherapy |
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Ichthyosiform Dermatoses- definition?
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group of hereditary disorders; characterized by fish-like skin; part of multiorgan syndromes
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Types of Ichthyosiform Dermatoses?
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DIV (Dominant ichthyosis vulgaris),
XLI (X-linked ichthyosis), LI (Lamellar ichthyosis), EH (epidermolytic hyperkeratosis) |
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ichthyosis dermatosis- physical exam findings?
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-abnormal s. corneum causes H20 loss & Vacuolization (keratin cell separation)
-blistering -hyperkeratosis -Worse in winter/dry climates & better in summer/temperate climates |
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ichthyosis dermatosis- treatment?
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-hydration
-keratolytic agents -systemic retinoids -lotions for dry scale removal (6% salicylic acid + propylene glycol + ethyl alcohol) |
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Collodian babies show what condition?
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ichthyosis dermatosis
(self limiting?) |
