Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
18 Cards in this Set
- Front
- Back
|
erythromycin, lincomycin and clindamycin are all what? what is their mechanism and target?
|
macrolides.
blocks protein synthesis. gram + (s. pseudintermedius) |
|
|
what species do you never want to give macrolides to? whats a big side effect in all animals?
|
rabbits.
potent CP450 inhibitor so decreases other drug metabolism |
|
|
what's the downside to erythromycin?
|
TID
|
|
|
T/F clindamycin has good bone penetration hehehhee.
|
true.
|
|
|
what are penicillins and cephalosporins? how do they work?
|
beta-lactam antibiotics
inhibit cell wall synthesis |
|
|
what's special about cefovecin?
|
99% protein bound and you only have to give it SQ every 2 weeks.
good to combat owner noncompliance. |
|
|
how to potentiated sulfonamides work?
what's a big side effect? |
inhibit folic acid synthesis
KCS. |
|
|
if using sulfonamides long term, what else should you give?
|
thyroid hormones.
|
|
|
when do you not want to use fluoroquinolones?
|
YOUNG animals b/c of cartilage damage
|
|
|
what are ciprofloxacin and enrofloxacin (all the floxacins)?
|
fluoroquinolones
|
|
|
T/F ciprofloxacin has good absorption.
|
false. variable in dogs and bad in cats.
|
|
|
how does baytril (enrofloxacin) get to inflammation sites?
|
carried in phagocytes!
|
|
|
what's special about tetracyclines?
|
anti-inflammatory so good with immune-mediated disease also with some anti-bacterial activity.
|
|
|
what's a good target for doxycycline and a side effect?
|
mycobacteria
esophageal irritation/strictures |
|
|
what's important about chloramphenicol? when do you not want to give it?
|
lipid soluble! wear gloves.
treat methicillin resistant junk. no preggers or neonates |
|
|
what's special about aminoglycosides and whats bad about them?
|
ear infections and gram (-) and need to give by injection
nephrotoxicity |
|
|
gent and amikacin are what class?
|
aminoglycosides
|
|
|
what absorption and distribution does rifampin have and what are some problems?
|
excellent both.
fast resistance and red urine and hepatotoxicity |
